anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) Antibodies

CYP2A6, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2A6 Kits (4) and CYP2A6 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP2A6 1548 P11509
CYP2A6    
CYP2A6    
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Top anti-CYP2A6 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using Cytochrome P450 2A6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-CYP2A6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: COLO205 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CYP2A6 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Small Intestine 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2A6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2A6. Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (ABIN2455426) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB HEK293T cells transfected with either RC222995 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-CYP2A6 antibody (ABIN2455203), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2A6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2A6. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2A6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2A6. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated ELISA, IF, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (fro), WB 0.2 mg Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of Cytochrome P450 2A6 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of Cytochrome P450 2A6 expression in HeLa (A), Jurkat (B), MCF7 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details

CYP2A6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CYP2A6 Antibodies

  1. Human Polyclonal CYP2A6 Primary Antibody for WB - ABIN2801900 : Miles, Bickmore, Brook, McLaren, Meehan, Wolf: Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity. in Nucleic acids research 1989 (PubMed)
    Show all 4 references for 2801900

  2. Human Polyclonal CYP2A6 Primary Antibody for ELISA, WB - ABIN1534381 : Yamano, Tatsuno, Gonzalez: The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. in Biochemistry 1990 (PubMed)

More Antibodies against CYP2A6 Interaction Partners

Pig (Porcine) Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) interaction partners

  1. Polymorphisms within the CYP2A6 gene are not a significant cause of high skatole levels.

Human Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) interaction partners

  1. CYP2A6 activity provides information on lung cancer risk that is not captured by smoking history.

  2. CYP2A6*4 genetic polymorphisms may not strongly affect smoking behavior but may possibly have an effect on nicotine dependence

  3. CYP2A6 genetic variation alters striatal-cingulate circuits, network hubs, and executive processing in smokers. Because the CYP2A6 effect was seen only in smokers, these data suggest that the rate of nicotine metabolism-and thus the concentration of nicotine presented to the brain over the course of nicotine addiction-shapes brain circuits that, among other functions, compute reward and impulsivity processes.

  4. a greater CYP2A6 activity causes smokers to smoke more extensively and be exposed to higher levels of carcinogens, resulting in an increased risk for lung cancer.

  5. Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype

  6. We conducted a genome-wide association study (GWAS) of plasma caffeine, paraxanthine, theophylline, theobromine and paraxanthine/caffeine ratio. A single SNP at 6p23 (near CD83 (show CD83 Antibodies)) and several SNPs at 7p21 (near AHR (show AHR Antibodies)), 15q24 (near CYP1A2 (show CYP1A2 Antibodies)) and 19q13.2 (near CYP2A6) met GW-significance (P < 5 x 10-8) and were associated with one or more metabolites

  7. study demonstrated a strong dose-dependent association between reduced CYP2A6 activity determined by genotypes and reduced risk of lung cancer

  8. Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank

  9. drug and the major metabolites were compared with the kinsenoside-cotreated samples. The effect of kinsenoside was negligible on the enzyme activity of all the CYP (show PPIG Antibodies) isozymes tested even though CYP2A6 was slightly inhibited at higher concentrations.

  10. CYP2A6 gene variants were associated with markedly reduced nicotine and cotinine clearances.

CYP2A6 Antigen Profile

Protein Summary

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3\; however, it has been renamed CYP2A6.

Gene names and symbols associated with CYP2A6

  • cytochrome P450 2A19 (CYP2A19) antibody
  • cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6) antibody
  • CPA6 antibody
  • CYP2A antibody
  • CYP2A3 antibody
  • CYP2A6 antibody
  • CYPIIA6 antibody
  • P450C2A antibody
  • P450PB antibody

Protein level used designations for CYP2A6

coumarin 7-hydroxylase , cytochrome p450 2A6 , 1,4-cineole 2-exo-monooxygenase , cytochrome P450 2A6 , cytochrome P450 IIA3 , cytochrome P450(I) , cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 , flavoprotein-linked monooxygenase , xenobiotic monooxygenase

GENE ID SPECIES
403149 Sus scrofa
1548 Homo sapiens
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