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CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2B6 Kits (12) and CYP2B6 Proteins (3) and many more products for this protein.
Showing 10 out of 62 products:
Human Monoclonal CYP2B6 Primary Antibody for FACS, IF - ABIN2455580
Sim, Nam, Lee, Lee, O, Joo, Liu, Han, Ki, Jeong, Lee, Lee: Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer. in Archives of pharmacal research 2015
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Human Polyclonal CYP2B6 Primary Antibody for IF, IHC (p) - ABIN655056
Bunten, Liang, Pounder, Seneviratne, Osselton: OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths. in Clinical pharmacology and therapeutics 2010
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Genetic polymorphisms in CYP2B6 and CYP2A6 (show CYP2A6 Antibodies) explained a significant proportion of variability in EFV plasma concentration in HIV-infected children in a multi-ethnic outpatient clinic.
CYP2B6/CYP2A6 (show CYP2A6 Antibodies) genotypes were associated with increased reported suicidality among AIDS patients who had been randomly assigned to receive efavirenz-containing regimens in clinical trials. Strength of association varied by race/ethnicity.
CYP2B6 SNPs are associated with methadone fatalities. contributes to a poor metabolizer phenotype for methadone in these fatal cases
CYP2B6 rs2279343 may predict event-free survival in rhabdomyosarcoma
It has been established that cytochrome P4502B6 (CYP2B6) is the major isoform catalyzing both ketamine N-demethylation and ketamine metabolism overall in vitro at therapeutic concentrations and clinically.
polymorphism c.516G>T in the CYP2B6 gene and BMI affect the metabolism rate of propofol and may play an important role in the optimisation of propofol anaesthesia
his cross-sectional, pharmacogenetic candidate, gene pilot study recruited 75 patients having minor elective outpatient surgeries. EP was measured with the Clinician Administered Dissociative State Scale. Genetic association of CYP2B6*6 and GRIN2B (show GRIN2B Antibodies) (rs1019385 and rs1806191) single-nucleotide polymorphisms and ketamine-induced EP occurrence and severity were tested using logistic and linear regression.
Data suggest that A785G CYP2B6 gene polymorphisms and specific CYP2B6 haplotypes may be a risk factor for the pathogenesis of AML (show RUNX1 Antibodies), especially secondary AML (show RUNX1 Antibodies) as well as for the induction of AML (show RUNX1 Antibodies) chromosomal aberrations.
Results show that CYP2B6 slow metabolizer genotypes were significantly associated with efavirenz induced central nervous system symptoms.
The possible influence of CYP2B6 c.516G>T genetic variant on propofol dose.
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
cytochrome P450 2B6
, cytochrome P450 CYP2B30
, cytochrome P450, family 2, subfamily B, polypeptide 6
, cytochrome P450 PBD-2
, cytochrome P450, family 2, subfamily B, polypeptide 11
, cytochrome P450 2B3
, cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
, cytochrome P450IIB3
, 1,4-cineole 2-exo-monooxygenase
, cytochrome P450 IIB1