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anti-Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) Antibodies

CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2B6 Kits (12) and CYP2B6 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP2B6 286953 P13107
CYP2B6 1555 P20813
CYP2B6    
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Top anti-CYP2B6 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CYP2B6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2B6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of CYP2B6 Antibody (Center) (ABIN655056) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of CYP2B6 Antibody (Center) Cat.-No AP51170PU-N with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Formalin fixed, paraffin embedded human hepatocarcinoma stained with CYP2B6 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CYP2B6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-CYP2B6 mouse monoclonal antibody (ABIN2455580) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2B6 (RC217236). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2B6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2B6. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$175.80
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Cytochrome P450 2B6 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytochrome P450 2B6 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Cow Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$451.00
Details

CYP2B6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CYP2B6 Antibodies

  1. Human Polyclonal CYP2B6 Primary Antibody for EIA, IF - ABIN951782 : Cabrera Figueroa, Fernández de Gatta, Hernández García, Domínguez-Gil Hurlé, Bustos Bernal, Sepúlveda Correa, García Sánchez: The convergence of therapeutic drug monitoring and pharmacogenetic testing to optimize efavirenz therapy. in Therapeutic drug monitoring 2010 (PubMed)
    Show all 4 references for ABIN951782

  2. Human Polyclonal CYP2B6 Primary Antibody for ELISA, WB - ABIN1534383 : Yamano, Nhamburo, Aoyama, Meyer, Inaba, Kalow, Gelboin, McBride, Gonzalez et al.: cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression ... in Biochemistry 1990 (PubMed)
    Show all 3 references for ABIN1534383

  3. Human Monoclonal CYP2B6 Primary Antibody for FACS, IF - ABIN2455580 : Sim, Nam, Lee, Lee, O, Joo, Liu, Han, Ki, Jeong, Lee, Lee: Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer. in Archives of pharmacal research 2015 (PubMed)
    Show all 2 references for ABIN2455580

  4. Human Polyclonal CYP2B6 Primary Antibody for IF, IHC (p) - ABIN655056 : Bunten, Liang, Pounder, Seneviratne, Osselton: OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths. in Clinical pharmacology and therapeutics 2010 (PubMed)
    Show all 2 references for ABIN655056

  5. Cow (Bovine) Polyclonal CYP2B6 Primary Antibody for WB - ABIN2777002 : Ekhart, Doodeman, Rodenhuis, Smits, Beijnen, Huitema: Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide. in Pharmacogenetics and genomics 2008 (PubMed)

More Antibodies against CYP2B6 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) interaction partners

  1. It has been established that cytochrome P4502B6 (CYP2B6) is the major isoform catalyzing both ketamine N-demethylation and ketamine metabolism overall in vitro at therapeutic concentrations and clinically.

  2. polymorphism c.516G>T in the CYP2B6 gene and BMI affect the metabolism rate of propofol and may play an important role in the optimisation of propofol anaesthesia

  3. his cross-sectional, pharmacogenetic candidate, gene pilot study recruited 75 patients having minor elective outpatient surgeries. EP was measured with the Clinician Administered Dissociative State Scale. Genetic association of CYP2B6*6 and GRIN2B (show GRIN2B Antibodies) (rs1019385 and rs1806191) single-nucleotide polymorphisms and ketamine-induced EP occurrence and severity were tested using logistic and linear regression.

  4. Data suggest that A785G CYP2B6 gene polymorphisms and specific CYP2B6 haplotypes may be a risk factor for the pathogenesis of AML (show RUNX1 Antibodies), especially secondary AML (show RUNX1 Antibodies) as well as for the induction of AML (show RUNX1 Antibodies) chromosomal aberrations.

  5. Results show that CYP2B6 slow metabolizer genotypes were significantly associated with efavirenz induced central nervous system symptoms.

  6. The possible influence of CYP2B6 c.516G>T genetic variant on propofol dose.

  7. Around 450 and 250 mg daily doses might meet EFV dosing needs of HIV-TB infected Ugandans in general and CYP2B6*6/*6 genotypes, respectively.

  8. CYP2B6 polymorphisms were associated with lower and higher plasma concentrations in pregnant and postpartum women.

  9. Analysis of gene-gene interactions with CYP2B6 was particularly useful to reinforce the role of MRP4 (show ABCC4 Antibodies) and to reveal unknown associations, such as that of DRD3 (show DRD3 Antibodies).

  10. POR (show POR Antibodies) rs2868177 and CYP2B6*6 variants contribute to the interindividual variability in human CYP2B6 activity, which may affect the disposition and interaction of other CYP2B6 substrate drugs

CYP2B6 Antigen Profile

Protein Summary

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Gene names and symbols associated with CYP2B6

  • cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6) antibody
  • cytochrome P450, family 2, subfamily B, polypeptide 6 (cyp2b6) antibody
  • cytochrome P450 2B11 (CYP2B6) antibody
  • cytochrome P450, family 2, subfamily b, polypeptide 3 (Cyp2b3) antibody
  • CPB6 antibody
  • CYP2B antibody
  • Cyp2b6 antibody
  • CYP2B7 antibody
  • CYP2B7P antibody
  • CYP2B11 antibody
  • CYP2B30 antibody
  • CYPIIB6 antibody
  • CYPIIB11 antibody
  • EFVM antibody
  • IIB1 antibody
  • P450 antibody

Protein level used designations for CYP2B6

cytochrome P450 2B6 , cytochrome P450 CYP2B30 , cytochrome P450, family 2, subfamily B, polypeptide 6 , cytochrome P450 PBD-2 , cytochrome P450, family 2, subfamily B, polypeptide 11 , CYPIIB3 , cytochrome P450 2B3 , cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 , cytochrome P450IIB3 , 1,4-cineole 2-exo-monooxygenase , cytochrome P450 IIB1

GENE ID SPECIES
678687 Macaca mulatta
494798 Xenopus laevis
474177 Canis lupus familiaris
286953 Rattus norvegicus
1555 Homo sapiens
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