Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 Proteins (CYP2B6)

CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2B6 Antibodies (56) and CYP2B6 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CYP2B6 CYP2B6 286953 P13107
CYP2B6 1555 P20813
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Top CYP2B6 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

CYP2B6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
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More Proteins for Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) interaction partners

  1. CYP2B6 SNPs are associated with methadone fatalities. contributes to a poor metabolizer phenotype for methadone in these fatal cases

  2. CYP2B6 rs2279343 may predict event-free survival in rhabdomyosarcoma

  3. It has been established that cytochrome P4502B6 (CYP2B6) is the major isoform catalyzing both ketamine N-demethylation and ketamine metabolism overall in vitro at therapeutic concentrations and clinically.

  4. polymorphism c.516G>T in the CYP2B6 gene and BMI affect the metabolism rate of propofol and may play an important role in the optimisation of propofol anaesthesia

  5. his cross-sectional, pharmacogenetic candidate, gene pilot study recruited 75 patients having minor elective outpatient surgeries. EP was measured with the Clinician Administered Dissociative State Scale. Genetic association of CYP2B6*6 and GRIN2B (show GRIN2B Proteins) (rs1019385 and rs1806191) single-nucleotide polymorphisms and ketamine-induced EP occurrence and severity were tested using logistic and linear regression.

  6. Data suggest that A785G CYP2B6 gene polymorphisms and specific CYP2B6 haplotypes may be a risk factor for the pathogenesis of AML (show RUNX1 Proteins), especially secondary AML (show RUNX1 Proteins) as well as for the induction of AML (show RUNX1 Proteins) chromosomal aberrations.

  7. Results show that CYP2B6 slow metabolizer genotypes were significantly associated with efavirenz induced central nervous system symptoms.

  8. The possible influence of CYP2B6 c.516G>T genetic variant on propofol dose.

  9. Around 450 and 250 mg daily doses might meet EFV dosing needs of HIV-TB infected Ugandans in general and CYP2B6*6/*6 genotypes, respectively.

  10. CYP2B6 polymorphisms were associated with lower and higher plasma concentrations in pregnant and postpartum women.

CYP2B6 Protein Profile

Protein Summary

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Gene names and symbols associated with CYP2B6

  • cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6)
  • cytochrome P450, family 2, subfamily B, polypeptide 6 (cyp2b6)
  • cytochrome P450 2B11 (CYP2B6)
  • cytochrome P450, family 2, subfamily b, polypeptide 3 (Cyp2b3)
  • CPB6 protein
  • CYP2B protein
  • Cyp2b6 protein
  • CYP2B7 protein
  • CYP2B7P protein
  • CYP2B11 protein
  • CYP2B30 protein
  • CYPIIB6 protein
  • CYPIIB11 protein
  • EFVM protein
  • IIB1 protein
  • P450 protein

Protein level used designations for CYP2B6

cytochrome P450 2B6 , cytochrome P450 CYP2B30 , cytochrome P450, family 2, subfamily B, polypeptide 6 , cytochrome P450 PBD-2 , cytochrome P450, family 2, subfamily B, polypeptide 11 , CYPIIB3 , cytochrome P450 2B3 , cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 , cytochrome P450IIB3 , 1,4-cineole 2-exo-monooxygenase , cytochrome P450 IIB1

678687 Macaca mulatta
494798 Xenopus laevis
474177 Canis lupus familiaris
286953 Rattus norvegicus
1555 Homo sapiens
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