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CYP2C18 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily C, Polypeptide 18 Antibodies (18) and Cytochrome P450, Family 2, Subfamily C, Polypeptide 18 Kits (1) and many more products for this protein.
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These results suggest that there is no notable influence of sequence variation in the CYP2C genes on longevity in the examined German population
Despite the observed alterations, tg-CYP2C18&19 did not show any macroscopic or microscopic pathology at the examined age. Hence, these hemizygous transgenic mice were considered to be viable and healthy animals.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist\\\\; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
(S)-mephenytoin hydroxylase associated cytochrome P450
, cytochrome P450 2C18
, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17
, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18
, cytochrome P450-6B/29C
, flavoprotein-linked monooxygenase
, microsomal monooxygenase
, unspecific monooxygenase
, cytochrome P450 2H2
, cytochrome P450 PCHP7
, cytochrome P450, family 2, subfamily C, polypeptide 18