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Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 Proteins (CYP2C19)

CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Antibodies (28) and CYP2C19 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP2C19 1557 P33261
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Top CYP2C19 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Yeast (Pichia pastoris) Human Un-conjugated   10 mg Log in to see 2 to 3 Days
$157.50
Details

CYP2C19 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) interaction partners

  1. The resi=ults of this study showed that the CYP2C19 loss of function alleles may increase the recurrent risk of ischemic events.

  2. Data suggest that CYP2C19- (cytochrome P450 2C19-) dependent omeprazole oxidation activities in liver microsomes of cynomolgus monkeys and common marmosets exhibit individual variations suggestive of genetic polymorphisms similar to those seen in humans.

  3. Carriers of CYP2C19 loss-of-function alleles (*2, *3, and *8) were at increased risk of stroke and composite vascular events in comparison with noncarriers among patients with ischemic stroke or transient ischemic attack treated with clopidogrel.

  4. Study investigated the effect of MDR1, CYP2D6 (show CYP2D6 Proteins) and CYP2C19 gene polymorphisms on prophylactic therapy response in migraine patients, suggested that migraine patients who receive topiramate prophylactic treatment should be assessed for the presence of the MDR1 C3435T polymorphism

  5. CYP2C19 single nucleotide polymorphisms are associated with Clopidogrel Resistance in Acute Ischemic Stroke.

  6. This study was aimed to describe the distribution of CYP2C9 (show CYP2C9 Proteins) and CYP2C19 alleles and haplotypes in four Mestizo populations from Western Mexico. Frequencies ranged from 2.2-3.0% and 4.8-8.9% for CYP2C9 (show CYP2C9 Proteins)*3 and CYP2C9 (show CYP2C9 Proteins)*2 alleles, respectively, and 5.4-12.0% for CYP2C19*2, whereas the CYP2C19*3 allele was not found.

  7. CYP2C19 genotyping or on-clopiodgrel platelet reactivity was an independent risk predictor of major adverse cardiac events in Chinese patients treated with clopidogrel and undergoing stent implantation.

  8. pharmacogenetic analysis of CYP2C19 variants affecting metabolism of clopidogrel in Czech patients after percutaneous coronary intervention using MassARRAY genotyping

  9. CYP2C19 enzyme induction is predominant in patients after 1 month of antituberculosis treatment.

  10. Our study shows that after the Acute Coronary Syndrome patients with CYP2C19 polymorphism underwent Percutaneous Coronary Intervention , ticagrelor had better inhibitory effects on platelet aggregation compared to clopidogrel , and the use of ticagrelor is superior to clopidogrel in emergency interventions

CYP2C19 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C19

  • cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19)
  • CPCJ protein
  • CYP2C protein
  • P450C2C protein
  • P450IIC19 protein

Protein level used designations for CYP2C19

cytochrome P450 2C , (R)-limonene 6-monooxygenase , (S)-limonene 6-monooxygenase , (S)-limonene 7-monooxygenase , CYPIIC17 , CYPIIC19 , S-mephenytoin 4-hydroxylase , cytochrome P-450 II C , cytochrome P450 2C19 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 , cytochrome P450-11A , cytochrome P450-254C , flavoprotein-linked monooxygenase , mephenytoin 4'-hydroxylase , mephenytoin 4-hydroxylase , microsomal monooxygenase , xenobiotic monooxygenase

GENE ID SPECIES
510380 Bos taurus
1557 Homo sapiens
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