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Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) ELISA Kits

CYP2C8 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C8 Antibodies (52) and CYP2C8 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CYP2C8 CYP2C8 1558 P10632
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More ELISA Kits for CYP2C8 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) interaction partners

  1. This review focuses on recent findings of in vitro studies on drug metabolizing activity of 3 highly polymorphic CYP2C (show CYP2C19 ELISA Kits) members: CYP2C8, CYP2C9 (show CYP2C9 ELISA Kits), and CYP2C19 (show CYP2C19 ELISA Kits).

  2. CYP2C8*3 is a gain-of-function polymorphism for imatinib N-demethylation, which appears to be mainly mediated by CYP2C8 and not CYP3A4 (show CYP3A4 ELISA Kits) in vitro in human liver microsomes

  3. CYP2C8 genetic polymorphisms may influence outcome of taxane therapy in Roma and Hungarian populations.

  4. CYP2C8-derived epoxyeicosatrienoic acids prevented TNF-alpha (show TNF ELISA Kits)-induced HUVECs apoptosis via inhibition of oxidative stress associated with the Nrf2 (show GABPA ELISA Kits) signaling.

  5. Interaction among CYP2C8, EPHX2 (show EPHX2 ELISA Kits), and CYP4A11 (show CYP4A11 ELISA Kits) Gene Variants Significantly Increases the Risk for Ischemic Stroke.

  6. These comprehensive findings could inform for further genotype-phenotype studies on interindividual differences in CYP2C8-mediated drug metabolism

  7. Significant gene-sex interaction for CYP2C8*3 with twofold increase in the relative risk of essential hypertension and a similar tendency for CYP2J2 (show CYP2J2 ELISA Kits)*7 associated with coronary artery disease without myocardial infarction in Bulgarian males.

  8. We did not observe any association of CYP2C8*2, CYP2C8*3, CYP2C9 (show CYP2C9 ELISA Kits)*2 and CYP2C9 (show CYP2C9 ELISA Kits)*3 with myocardial infarction

  9. CYP2C8 polymorphisms affected neither R- nor S-ibuprofen

  10. the CYP2C8*3 allele has no major impact on paclitaxel metabolism in vitro or of paclitaxel-induced neuropathy

CYP2C8 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.

Gene names and symbols associated with CYP2C8

  • cytochrome P450, family 2, subfamily C, polypeptide 8 (CYP2C8) antibody
  • Cytochrome P450 2C8 (CTN_0597) antibody
  • cytochrome P450, family 2, subfamily C, polypeptide 8, gene 1 (cyp2c8.1) antibody
  • cytochrome P450, family 2, subfamily C, polypeptide 8, gene 2 (cyp2c8.2) antibody
  • cytochrome P450, family 2, subfamily C, polypeptide 8 (cyp2c8) antibody
  • CPC8 antibody
  • cyp2c8 antibody
  • CYP2C74 antibody
  • CYPIIC8 antibody
  • MP-12/MP-20 antibody

Protein level used designations for CYP2C8

cytochrome P450 2C8 , cytochrome P450 CYP2C74 , Cytochrome P450 2C8 , cytochrome P450, family 2, subfamily C, polypeptide 8 , P450 form 1 , cytochrome P450 IIC2 , cytochrome P450 MP-12 , cytochrome P450 MP-20 , cytochrome P450 form 1 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8 , flavoprotein-linked monooxygenase , microsomal monooxygenase , s-mephenytoin 4-hydroxylase , xenobiotic monooxygenase

GENE ID SPECIES
678683 Macaca mulatta
7378980 Thermotoga neapolitana DSM 4359
379297 Xenopus laevis
448236 Xenopus (Silurana) tropicalis
450909 Pan troglodytes
100127852 Xenopus (Silurana) tropicalis
1558 Homo sapiens
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