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CYP2D6 Proteins

(Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

recommended

CYP2D6 Protein (AA 91-190) (GST tag) (ABIN1350974)

CYP2D6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

CYP2D6 Protein (AA 1-497) (Strep Tag) (ABIN3078040)

Crystallography grade CYP2D6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA

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recommended

CYP2D6 Protein (His tag) (ABIN7407760)

CYP2D6 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC

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CYP2D6 Proteins by Grade

Find CYP2D6 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CYP2D6 Proteins by Origin

Find CYP2D6 Proteins for a variety of species such as anti-Human CYP2D6, anti-Rat CYP2D6, anti-Bonobo CYP2D6. The species listed below are among those available. Click on a link to go to the corresponding products.

CYP2D6 Proteins by Source

Here you will find CYP2D6 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CYP2D6 Proteins by Protein Type

Here you can find CYP2D6 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CYP2D6 Proteins by Application

Find CYP2D6 Proteins validated for a specific application such as WB, ELISA, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CYP2D6 Proteins by Biological Activity

Find CYP2D6 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular CYP2D6 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CYP2D6 Protein (AA 91-190) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1350974

Quantity 10 μg

Datasheet Datasheet

CYP2D6 Protein (AA 1-497) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3078040

Quantity 1 mg

Datasheet Datasheet

CYP2D6 Protein (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7407760

Quantity 100 μg

Datasheet Datasheet

CYP2D6 Protein (AA 236-472) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7401203

Quantity 100 μg

Datasheet Datasheet

CYP2D6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2712768

Quantity 20 μg

Datasheet Datasheet

CYP2D6 Protein (DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2712769

Quantity 20 μg

Datasheet Datasheet

CYP2D6 Protein (AA 236-472) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6238518

Quantity 50 μg

Datasheet Datasheet

CYP2D6 Protein

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6378889

Quantity 1 mg

Datasheet Datasheet

CYP2D6 Protein (AA 1-497) (His tag)

Reactivity Bonobo

Source Yeast

Validations

Cat. No. ABIN1625688

Quantity 1 mg

Datasheet Datasheet

CYP2D6 Protein (AA 1-497) (His tag)

Reactivity Chimpanzee

Source Yeast

Validations

Cat. No. ABIN1625989

Quantity 1 mg

Datasheet Datasheet

CYP2D6 Protein

Reactivity Human

Source

Validations

Cat. No. ABIN1062431

Quantity 1 mg

Datasheet Datasheet

Aliases for CYP2D6 Proteins

cytochrome P450 family 2 subfamily D member 6 (CYP2D6) Proteins
cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) Proteins
cytochrome 2D6 (CYP2D6) Proteins
cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) Proteins
cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S) Proteins
cytochrome P450 family 2 subfamily D member 6 (cyp2d6) Proteins
cytochrome P450 2D6 (CYP2D6) Proteins
cytochrome P450 2D6-like (LOC100988273) Proteins
CPD6 Proteins
CYP2D Proteins
cyp2d2 Proteins
CYP2D6 Proteins
cyp2d6-a Proteins
CYP2D7AP Proteins
CYP2D7BP Proteins
CYP2D7P2 Proteins
CYP2D8P2 Proteins
CYP2D42 Proteins
CYP2DL1 Proteins
CYPIID6 Proteins
MGC64445 Proteins
P450-DB1 Proteins
P450C2D Proteins
P450DB1 Proteins

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CYP2D6 Proteins by Grade

CYP2D6 Proteins by Origin

CYP2D6 Proteins by Source

CYP2D6 Proteins by Protein Type

CYP2D6 Proteins by Application

CYP2D6 Proteins by Biological Activity

Popular CYP2D6 Proteins

Aliases for CYP2D6 Proteins

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