You are viewing an incomplete version of our website. Please click to reload the website as full version.

Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Proteins (CYP2D6)

CYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Antibodies (124) and Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CYP2D6 CYP2D6 171522 Q64680
CYP2D6 1565 P10635
CYP2D6    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
Yeast Pan paniscus His tag   1 mg Log in to see 56 to 66 Days
$3,408.17
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$3,408.17
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 2 to 3 Days
$189.00
Details
HOST_Sf-9 cells Human Biotin   1 mg Log in to see 3 to 4 Days
$3,978.07
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Yeast (Pichia pastoris) Human Un-conjugated   10 mg Log in to see 2 to 3 Days
$157.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details

CYP2D6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Pan paniscus

More Proteins for Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) interaction partners

  1. No evidence provide for the contribution of CYP2D6 polymorphism to either drug response or CC concentrations.

  2. Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol

  3. CYP2D6 genetic polymorphisms and phenotypes in Malaysian breast cancer patients for different ethnicities

  4. This study demonstrated that Clinical evaluation of analgesic ineffectiveness and adverse effects led to the high likelihood of identifying patients with CYP2D6, CYP2C19 (show CYP2C19 Proteins), and CYP2C9 (show CYP2C9 Proteins) alleles associated with alterations in analgesic metabolism.

  5. CYP2D6 copy number variation may account for the single most impactful genetic anomaly as it relates to pharmacogenetic directed therapies

  6. CYP2D6 polymorphisms are significantly associated with therapeutic responses to donepezil in patients with Alzheimer's disease.

  7. the first study to conduct functional analysis of CYP2D6 four novel high frequency alleles in Chinese Han population

  8. The study results may suggest the impact of CYP2D6 gene polymorphism (A2637 deletion) on a higher prevalence of bullous pemphigoid (show DST Proteins).

  9. In respect to the normal CYP2D6 phenotype, our results suggested that slowly metabolizers (IMs and PMs (show PRB1 Proteins)) might have a major sedation, whereas more rapid metabolizers (UM) a minor sedation.

  10. CYP2D6 genotype- and endoxifen-guided tamoxifen dose escalation increases endoxifen serum concentrations without increasing side effects

Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP2D6

  • cytochrome 2D6 (CYP2D6)
  • cytochrome P450 2D6 (CYP2D6)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6)
  • cytochrome P450, family 2, subfamily d, polypeptide 4 (Cyp2d4)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D14)
  • CPD6 protein
  • CYP2D protein
  • cyp2d2 protein
  • Cyp2d4v1 protein
  • Cyp2d4v2 protein
  • CYP2D6 protein
  • cyp2d6-a protein
  • CYP2D7AP protein
  • CYP2D7BP protein
  • CYP2D7P2 protein
  • CYP2D8P2 protein
  • Cyp2d18 protein
  • Cyp2d22 protein
  • CYP2D42 protein
  • CYP2DL1 protein
  • CYPIID6 protein
  • MGC64445 protein
  • P450-DB1 protein
  • P450C2D protein
  • P450DB1 protein

Protein level used designations for CYP2D6

cytochrome P450 2D6 , cytochrome P450 CYP2D42 , cytochrome P450, family 2, subfamily D, polypeptide 6 , CYPIID18 , CYPIID4 , Cytochrome P450, subfamily IID4 , P450 2D-29/2D-35 , P450-CMF3 , P450-DB4 , cytochrome P450 2D-29 , cytochrome P450 2D-35 , cytochrome P450 2D4 , cytochrome P450 2d18 , cytochrome P450, family 2, subfamily d, polypeptide 22 , cytochrome P450, subfamily 2D, polypeptide 6 , cytochrome P450, subfamily IID, polypeptide 6 , cytochrome P450-CMF3 , cytochrome P450-DB4 , debrisoquine 4-hydroxylase , cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 , cytochrome P450-DB1 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIID14 , cytochrome P450 2D14 , CYPIID6

GENE ID SPECIES
100500743 Felis catus
100568286 Ovis aries
678691 Macaca mulatta
379479 Xenopus laevis
446878 Xenopus laevis
548436 Xenopus (Silurana) tropicalis
171522 Rattus norvegicus
1565 Homo sapiens
282211 Bos taurus
470228 Pan troglodytes
Selected quality suppliers for Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Proteins (CYP2D6)
Did you look for something else?