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anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Antibodies

CYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Proteins (16) and Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP2D6 171522 Q64680
CYP2D6 1565 P10635
CYP2D6    
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Top anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Antibodies at antibodies-online.com

Showing 10 out of 124 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CYP2D6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: OVCAR-3 cell lysate WB Suggested Anti-CYP2D6  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: OVCAR-3 cell lysate  CYP2D6 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CYP2D6  Antibody Titration: 2.5 µg/mL  Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293/HuvEc/MCF-7 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB CYP2D6 Antibody (N-term) (ABIN658441) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the CYP2D6 antibody detected the CYP2D6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Rat Rabbit Un-conjugated IHC (p), WB Anti-Cytochrome P450 2D6 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Kidney Tissue Lysate Lane 3: Rat Brain Tissue Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details

CYP2D6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,


Human , ,
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Mouse (Murine) ,


Top referenced anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Antibodies

  1. Human Polyclonal CYP2D6 Primary Antibody for ELISA, WB - ABIN1534387 : Tyndale, Aoyama, Broly, Matsunaga, Inaba, Kalow, Gelboin, Meyer, Gonzalez: Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: possible association with the poor metabolizer phenotype. in Pharmacogenetics 1993 (PubMed)
    Show all 2 references for ABIN1534387

  2. Human Polyclonal CYP2D6 Primary Antibody for IHC, ELISA - ABIN1452036 : Gonzalez, Vilbois, Hardwick, McBride, Nebert, Gelboin, Meyer: Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22. in Genomics 1988 (PubMed)
    Show all 2 references for ABIN1452036

  3. Cow (Bovine) Polyclonal CYP2D6 Primary Antibody for IHC, WB - ABIN2776931 : Rowland, Blaney, Smyth, Jones, Leydon, Oxbrow, Lewis, Tennant, Modi, Eggleston, Chenery, Bridges: Crystal structure of human cytochrome P450 2D6. in The Journal of biological chemistry 2006 (PubMed)

  4. Cow (Bovine) Polyclonal CYP2D6 Primary Antibody for WB - ABIN2776932 : Halling, Weihe, Brosen: CYP2D6 polymorphism in relation to tramadol metabolism: a study of faroese patients. in Therapeutic drug monitoring 2008 (PubMed)

  5. Human Polyclonal CYP2D6 Primary Antibody for IHC (p), WB - ABIN658441 : Gao, Zhang, Cui, Akinyi: Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6. in Evidence-based complementary and alternative medicine : eCAM 2015 (PubMed)

More Antibodies against Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) interaction partners

  1. Studied frequency of ADRB1 (show ADRB1 Antibodies) Arginine389Glycine (Arg389Gly) and Cytochrome p450 2D6*10 (Cyp2D6*10) polymorphism in cases of heart failure-reduced ejection fraction (HFREF), and to evaluate the influence of the polymorphisms in response to beta-blocker (BB) therapy; found a statistically significant association was observed with CC genotype and Glisin-Glisin (GG) genotype.

  2. Variant genotypes of CYP2D6 are associated with an increased risk of esophageal squamous cell carcinoma in Kashmir, India.

  3. genetic variation in CYP2D6 is a key predictor for the response to tamoxifen in patients with breast cancer

  4. These results indicated that most of the allelic variants of CYP2D6 studied here, exhibited significantly decreased enzymatic activities towards methadone N-demethylation.

  5. Evaluation of CYP2D6 ultrarapid metabolism should take into account activity of the multiplied alleles to avoid potential misclassification.

  6. Of 830 patients with sickle cell disease, 621 (75%) had a CYP2D6 genotype result; 7.1% were ultra-rapid or possible ultra-rapid metabolizers, and 1.4% were poor metabolizers.

  7. The purpose of this study was to determine the magnitude of effect of CYP2D6 genotype (activity score) on the dose-exposure relationship for ATX and its metabolites in children and adolescents with ADHD.

  8. The kinetic parameters Km , Vmax and intrinsic clearance (Vmax /Km ) of N-desmethyltamoxifen were determined using CYP2D6 variants found in Chinese Han population.

  9. present data in vitro suggest that the newly found variants significantly reduced catalytic activities compared with CYP2D6.1; given that CYP2D6 protein activities could affect carvedilol plasma levels, these findings are greatly relevant to personalized medicine

  10. Study investigated the effect of MDR1 (show TBC1D9 Antibodies), CYP2D6 and CYP2C19 (show CYP2C19 Antibodies) gene polymorphisms on prophylactic therapy response in migraine patients, suggested that migraine patients who receive topiramate prophylactic treatment should be assessed for the presence of the MDR1 (show TBC1D9 Antibodies) C3435T polymorphism

Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP2D6

  • cytochrome 2D6 (CYP2D6) antibody
  • cytochrome P450 2D6 (CYP2D6) antibody
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) antibody
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) antibody
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6) antibody
  • cytochrome P450, family 2, subfamily d, polypeptide 4 (Cyp2d4) antibody
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D14) antibody
  • CPD6 antibody
  • CYP2D antibody
  • cyp2d2 antibody
  • Cyp2d4v1 antibody
  • Cyp2d4v2 antibody
  • CYP2D6 antibody
  • cyp2d6-a antibody
  • CYP2D7AP antibody
  • CYP2D7BP antibody
  • CYP2D7P2 antibody
  • CYP2D8P2 antibody
  • Cyp2d18 antibody
  • Cyp2d22 antibody
  • CYP2D42 antibody
  • CYP2DL1 antibody
  • CYPIID6 antibody
  • MGC64445 antibody
  • P450-DB1 antibody
  • P450C2D antibody
  • P450DB1 antibody

Protein level used designations for CYP2D6

cytochrome P450 2D6 , cytochrome P450 CYP2D42 , cytochrome P450, family 2, subfamily D, polypeptide 6 , CYPIID18 , CYPIID4 , Cytochrome P450, subfamily IID4 , P450 2D-29/2D-35 , P450-CMF3 , P450-DB4 , cytochrome P450 2D-29 , cytochrome P450 2D-35 , cytochrome P450 2D4 , cytochrome P450 2d18 , cytochrome P450, family 2, subfamily d, polypeptide 22 , cytochrome P450, subfamily 2D, polypeptide 6 , cytochrome P450, subfamily IID, polypeptide 6 , cytochrome P450-CMF3 , cytochrome P450-DB4 , debrisoquine 4-hydroxylase , cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 , cytochrome P450-DB1 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIID14 , cytochrome P450 2D14 , CYPIID6

GENE ID SPECIES
100500743 Felis catus
100568286 Ovis aries
678691 Macaca mulatta
379479 Xenopus laevis
446878 Xenopus laevis
548436 Xenopus (Silurana) tropicalis
171522 Rattus norvegicus
1565 Homo sapiens
282211 Bos taurus
470228 Pan troglodytes
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