anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Antibodies

CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Kits (44) and Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Proteins (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP2E1 1571 P05181
CYP2E1 13106 Q05421
CYP2E1 25086 P05182
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Top anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Antibodies at antibodies-online.com

Showing 10 out of 181 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- CYP2E1 antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cytochrome P450 2E1 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using Cytochrome P450 2E1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti-Cytochrome P450 2E1 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Mouse Liver Tissue Lysate Anti-Cytochrome P450 2E1 antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Goat Un-conjugated EIA, IHC (p), WB AP22383PU-N CYP2E1 antibody staining of paraffin embedded Human Liver at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. AP22383PU-N CYP2E1 antibody staining of Human Liver lysate at 0.05µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Cytochrome P450 2E1 Antibody [NBP1-85366] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85366] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85367] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85367] - Lane 1: Mouse liver tissue lysate.Lane 2: Rat liver tissue lysate 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Cytochrome P450 family 2 subfamily E polypeptide 1 P450II Polyclonal Antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details

CYP2E1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Antibodies

  1. Mouse (Murine) Polyclonal CYP2E1 Primary Antibody for IHC (p), WB - ABIN3044118 : Fan, Jiang, Wang, Tan, Zeng, Wang, Chen, Qu, Gonzalez, Huang, Bi: Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways. in Drug metabolism and disposition: the biological fate of chemicals 2014 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CYP2E1 Primary Antibody for WB - ABIN3043000 : Jiang, Fan, Wang, Chen, Zeng, Tan, Gonzalez, Huang, Bi: Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. in Toxicological sciences : an official journal of the Society of Toxicology 2014 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal CYP2E1 Primary Antibody for IHC (p), WB - ABIN3043821 : Chen, Sun, Han, Peng, Li, Liu, Lv, Liu, Zhou, Sun: Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P450 suppression. in World journal of gastroenterology 2009 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal CYP2E1 Primary Antibody for ELISA, IHC - ABIN4302103 : Niu, Yuan, Leng, Pang, Gu, Chen: CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls. in Medical oncology (Northwood, London, England) 2011 (PubMed)

  5. Human Polyclonal CYP2E1 Primary Antibody for IHC, IHC (p) - ABIN4302104 : Fagerberg, Hallström, Oksvold, Kampf, Djureinovic, Odeberg, Habuka, Tahmasebpoor, Danielsson, Edlund, Asplund, Sjöstedt, Lundberg, Szigyarto, Skogs, Takanen, Berling, Tegel, Mulder, Nilsson, Schwenk et al.: Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ... in Molecular & cellular proteomics : MCP 2014 (PubMed)

  6. Human Polyclonal CYP2E1 Primary Antibody for WB - ABIN514837 : De Bock, Colin, Boussery, Van Bocxlaer: Quantification of cytochrome 2E1 in human liver microsomes using a validated indirect ELISA. in Journal of pharmaceutical and biomedical analysis 2013 (PubMed)

  7. Human Polyclonal CYP2E1 Primary Antibody for IHC, IHC (p) - ABIN4302106 : Hou, Bukong, Kodys, Szabo: Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. in Alcoholism, clinical and experimental research 2013 (PubMed)

More Antibodies against Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Interaction Partners

Rabbit Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. The localization of CYP1A2 (show CYP1A2 Antibodies), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98

Human Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. Studied the possible relationship between cytochrome P450 (show CYP Antibodies), family 2, subfamily E and polypeptide 1 (show CYP Antibodies) (CYP2E1) polymorphisms with Kawasaki disease (KD). Found the KD patients with a CYP2E1 CC genotype of rs915906 demonstrated a greater proportion of coronary artery lesions (CALs (show CA8 Antibodies)) formation.

  2. The results suggest that changes in coumarin pharmacokinetics and CYP2E1 subcellular distribution contribute to resistance to coumarin-induced hepatic necrosis, while cytotoxicity of metabolic conjugates shown in vitro may contribute to bile duct damage upon repeated coumarin administration.

  3. Data suggest a homeostatic, gene dosage-insensitive regulation of CYP2E1 expression by unknown gene dosage compensation mechanisms.

  4. Data suggest that microRNA-214-3p (but not microRNA-942-5p) suppresses expression of CYP2E1 in hepatocytes; microRNA-214-3p interacts with two binding sites located in protein coding region of CYP2E1 mRNA. (CYP2E1 = cytochrome P450 (show CYP Antibodies) family 2 subfamily E member 1)

  5. The synergistic effect of VK2 and EtOH was also observed in QGY-7703 cells, which also express CYP2E1. However, in HepG2 cells, which do not express CYP2E1, the synergistic effect of VK2 and EtOH was not observed

  6. The results suggest that there is no evidence for a major role of CYP2E1 polymorphism in liver carcinogenesis, but do not rule out the possibility in certain cases. [meta-analysis]

  7. The CYP2E1-PPARalpha (show PPARA Antibodies) axis may play a role in ethanol-induced neurotoxicity via the alteration of the genes related with synaptic function

  8. Results demonstrated that CYP2E1*5B and CYP2E1*6 minor alleles play a role in the development of sporadic colorectal neoplasms.

  9. This meta-analysis suggests that there is an increased risk of antituberculosis drug-induced hepatotoxicity in individuals carrying the C1/C1 genotype of the CYP2E1 RsaI/PstI (show SPINK1 Antibodies) polymorphism; however, no association was found for the DraI polymorphism

  10. NS5A contributes to reactive oxygen species production by activating expression of NADPH (show NQO1 Antibodies) oxidases 1 and 4 as well as cytochrome P450 2E1.

Mouse (Murine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.

  2. Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (show DHCR24 Antibodies)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (show DHCR24 Antibodies)-induced liver damage

  3. CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.

  4. Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice

  5. Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (show TP53 Antibodies), p21 (show D4S234E Antibodies), CCND1 (show CCND1 Antibodies), PCNA (show PCNA Antibodies), and BCL-2 (show BCL2 Antibodies) to promote liver regeneration.

  6. Studied hepatic stellate cell cytoglobin (show CYGB Antibodies) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.

  7. Data suggest that expression of Cyp2e1 in adipose tissue can be regulated by dietary factors; here, expression of Cyp2e1 in white adipose tissue is down-regulated in obesity caused by high-fat diet.

  8. The Cyp2e1-null mice displayed a susceptibility to lung toxicity of styrene similar to that of the wild-type animals; however, Cyp2f2-null mice were resistant to styrene-induced pulmonary toxicity.

  9. significant increases in Col1a1 (show COL1A1 Antibodies), serine/threonine-protein kinase 1, Ctnnb1 (show CTNNB1 Antibodies), CSRNP1 (show CSRNP1 Antibodies), Ddit4 (show DDIT4 Antibodies), Cyp2e1, and Krit1 (show KRIT1 Antibodies) expressions and great decreases inreceptor D2, Neu1 (show NEURL Antibodies), and Dhcr7 (show DHCR7 Antibodies) expressions following long-term exposure to TiO2 NPs (show NPS Antibodies)

  10. ATF4 (show ATF4 Antibodies) expression in the liver is responsible for the protective effects against high fat diet-induced CYP2E1 expression.

Pig (Porcine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.

  2. The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.

Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Gene names and symbols associated with CYP2E1

  • cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1) antibody
  • cytochrome P450 2E1 (CYP2E1) antibody
  • cytochrome P450 2E1 (PTRG_07411) antibody
  • Cytochrome P450 2E1-like (LOC100342572) antibody
  • cytochrome P450 2E1-like (LOC100727914) antibody
  • cytochrome P450 2E1-like (LOC101843716) antibody
  • cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1) antibody
  • CPE1 antibody
  • Cyp2e antibody
  • CYP2E1 antibody
  • CYPIIE1 antibody
  • P450-J antibody
  • P450C2E antibody

Protein level used designations for CYP2E1

cytochrome P450 2E1 , 4-nitrophenol 2-hydroxylase , Cytochrome P450 2E1 , Cytochrome P450 LM3A , Cytochrome P450 isozyme 3A , Cytochrome P450-ALC , Cytochrome P450-J , cytochrome P-450j , CYPIIE1 , cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , cytochrome P450-J , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , cytochrome P450, 2e1, ethanol inducible , cytochrome P450-ALC , P450-J , P450RLM6 , cytochrome P450 subfamily 2e1 (ethanol-inducible) , cytochrome P450, subfamily 2E, polypeptide 1 , cytochrome P450RLM6 , cytochrome P-450-J , cytochrome P450 CYP2E1

GENE ID SPECIES
100066422 Equus caballus
554344 Felis catus
6345684 Pyrenophora tritici-repentis Pt-1C-BFP
100342572 Oryctolagus cuniculus
100727914 Cavia porcellus
101843716 Mesocricetus auratus
1571 Homo sapiens
415128 Canis lupus familiaris
13106 Mus musculus
25086 Rattus norvegicus
403216 Sus scrofa
282213 Bos taurus
100568285 Ovis aries
678688 Macaca mulatta
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