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CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Kits (42) and Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Proteins (22) and many more products for this protein.
Showing 10 out of 177 products:
Human Polyclonal CYP2E1 Primary Antibody for IF, IHC - ABIN1534388
Umeno, McBride, Yang, Gelboin, Gonzalez: Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression. in Biochemistry 1989
Show all 2 references for ABIN1534388
Human Polyclonal CYP2E1 Primary Antibody for IHC, IHC (p) - ABIN4302104
Fagerberg, Hallström, Oksvold, Kampf, Djureinovic, Odeberg, Habuka, Tahmasebpoor, Danielsson, Edlund, Asplund, Sjöstedt, Lundberg, Szigyarto, Skogs, Takanen, Berling, Tegel, Mulder, Nilsson, Schwenk et al.: Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ... in Molecular & cellular proteomics : MCP 2014
Human Polyclonal CYP2E1 Primary Antibody for ELISA, IHC - ABIN4302103
Niu, Yuan, Leng, Pang, Gu, Chen: CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls. in Medical oncology (Northwood, London, England) 2011
Chicken Polyclonal CYP2E1 Primary Antibody for WB - ABIN2776801
Dey, Kessova, Cederbaum: Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1. in Archives of biochemistry and biophysics 2006
Human Polyclonal CYP2E1 Primary Antibody for IHC, IHC (p) - ABIN4302106
Hou, Bukong, Kodys, Szabo: Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. in Alcoholism, clinical and experimental research 2013
The localization of CYP1A2 (show CYP1A2 Antibodies), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98
This meta-analysis suggests that there is an increased risk of antituberculosis drug-induced hepatotoxicity in individuals carrying the C1/C1 genotype of the CYP2E1 RsaI/PstI (show SPINK1 Antibodies) polymorphism; however, no association was found for the DraI polymorphism
NS5A contributes to reactive oxygen species production by activating expression of NADPH (show NQO1 Antibodies) oxidases 1 and 4 as well as cytochrome P450 2E1.
This meta-analysis suggests that the CYP2E1 polymorphisms contributed to the susceptibility of nasopharyngeal carcinoma, especially in Asian populations.
Study indicate that ALDH2 (show ALDH2 Antibodies) Glu487Lys and CYP4502E1 polymorphisms could be risk factors for the development of gastric cancer in the Chinese population.
genetic association studies in population in Italy: Data suggest that SNPs in CYP2E1 are associated with differentiated thyroid carcinoma.
CYP2E1 RsaI/PstI (show SPINK1 Antibodies) polymorphisms may modify the susceptibility to HNC (show MMP8 Antibodies), particularly among Asians, mixed population, and never-smokers.
CYP2E1 rs2031920 and COMT (show COMT Antibodies) rs4680 are not major contributors to lung cancer risk.
Single nucleotide polymorphism in CYP2E1 gene is Associated with Breast Cancer.
background prevalence of CYP2E1*B polymorphism and their activity in Western Indian population was observed. The study suggests no association between the CYP2E1 genotyping with antituberculous drug-induced hepatotoxicity
This meta-analysis suggests that the CYP2E1 RsaI/PstI (show SPINK1 Antibodies) polymorphisms are a risk factor for developing oral cancer
Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.
Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (show DHCR24 Antibodies)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (show DHCR24 Antibodies)-induced liver damage
CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.
Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice
Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (show TP53 Antibodies), p21 (show D4S234E Antibodies), CCND1 (show CCND1 Antibodies), PCNA (show PCNA Antibodies), and BCL-2 (show BCL2 Antibodies) to promote liver regeneration.
Studied hepatic stellate cell cytoglobin (show CYGB Antibodies) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.
Data suggest that expression of Cyp2e1 in adipose tissue can be regulated by dietary factors; here, expression of Cyp2e1 in white adipose tissue is down-regulated in obesity caused by high-fat diet.
The Cyp2e1-null mice displayed a susceptibility to lung toxicity of styrene similar to that of the wild-type animals; however, Cyp2f2-null mice were resistant to styrene-induced pulmonary toxicity.
significant increases in Col1a1 (show COL1A1 Antibodies), serine/threonine-protein kinase 1, Ctnnb1 (show CTNNB1 Antibodies), CSRNP1 (show CSRNP1 Antibodies), Ddit4 (show DDIT4 Antibodies), Cyp2e1, and Krit1 (show KRIT1 Antibodies) expressions and great decreases inreceptor D2, Neu1 (show NEURL Antibodies), and Dhcr7 (show DHCR7 Antibodies) expressions following long-term exposure to TiO2 NPs (show NPS Antibodies)
ATF4 (show ATF4 Antibodies) expression in the liver is responsible for the protective effects against high fat diet-induced CYP2E1 expression.
A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.
The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
cytochrome P450 2E1
, 4-nitrophenol 2-hydroxylase
, Cytochrome P450 2E1
, Cytochrome P450 LM3A
, Cytochrome P450 isozyme 3A
, Cytochrome P450-ALC
, Cytochrome P450-J
, cytochrome P-450j
, cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1
, cytochrome P450-J
, flavoprotein-linked monooxygenase
, microsomal monooxygenase
, xenobiotic monooxygenase
, cytochrome P450, 2e1, ethanol inducible
, cytochrome P450-ALC
, cytochrome P450 subfamily 2e1 (ethanol-inducible)
, cytochrome P450, subfamily 2E, polypeptide 1
, cytochrome P450RLM6
, cytochrome P-450-J
, cytochrome P450 CYP2E1