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Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) ELISA Kits

CYP3A4 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP3A4 Antibodies (118) and CYP3A4 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP3A4 1576 P08684
CYP3A4    
CYP3A4    
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Top CYP3A4 ELISA Kits at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.62 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Human 5.8 pg/mL 23.5-1500 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$832.86
Details
Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$785.71
Details
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$801.43
Details
Monkey 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$832.86
Details
Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$801.43
Details
Pig
  96 Tests Log in to see 11 to 13 Days
$801.43
Details
Chicken
  96 Tests Log in to see 11 to 13 Days
$832.86
Details
Sheep
  96 Tests Log in to see 11 to 13 Days
$832.86
Details

More ELISA Kits for CYP3A4 Interaction Partners

Horse (Equine) Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR ELISA Kits) and cytochrome b(5 (show CYB5A ELISA Kits)).

Human Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. Metabolism of amiodarone to desethylamiodarone by CYP1A1 (show CYP1A1 ELISA Kits) or CYP3A4 plays an important role in the hepatocellular toxicity of amiodarone.

  2. Report roles for CYP3A4 and CYP2C9 (show CYP2C9 ELISA Kits) in sequential two-step bioactivation of diclofenac to reactive p-benzoquinone imines.

  3. SLCO1B1 (show SLCO1B1 ELISA Kits) rs113681054, SLCO1B1 (show SLCO1B1 ELISA Kits)*5 (rs4149056), CYP3A4*1G (rs2242480), and CYP3A4*5 (rs776746) polymorphisms had no effect on the PK/PD of ticagrelor in healthy Chinese volunteers

  4. Data suggest that CYP3A4 (cytochrome P-450 (show CYP ELISA Kits) 3A4) is involved in proliferation, migration, invasion, and colony formation abilities of hepatocellular carcinoma cells; in HEPG2 cells, the naturally occurring flavonoid rutin (an antioxidant anticarcinogen) inhibits progression (inhibits proliferation, migration, etc.), promotes apoptosis, and down-regulates expression of CYP3A4.

  5. effector-dependent conformational equilibrium between open and closed states of CYP3A4

  6. The combination of an in vivo drug-drug interaction (DDI) study with NVS123 and the potent CYP3A4 inhibitor ritonavir in hCYP3A4 mice along with physiologically based pharmacokinetic modeling modeling allowed for a prospective prediction of the extent of DDI and boost effect in humans, which was subsequently confirmed in a clinical study.

  7. Suggest that benzbromarone is a mechanism-based CYP3A4 inhibitor.

  8. This study found significant changes in the disposition of lidocaine hydrochloride in native healthy Tibetan and Han Chinese subjects living at a high altitude in comparison to healthy Han Chinese subjects living at low altitude, which might be due to significant decreases in the activity and protein and mRNA expression of CYP3A4 under chronic high altitude hypoxia condition.

  9. CYP2D6 and CYP3A activities were shown to have moderate contribution on clearance of tramadol enantiomers.

  10. decreases of CES and CYP3A4 expression and enzymatic activities induced by Fluoxetine are through decreasing PXR (show NR1I2 ELISA Kits) and increasing DEC1 (show BHLHE40 ELISA Kits) in HepG2 cells

CYP3A4 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with CYP3A4

  • cytochrome P450 3A4 (PTRG_01782) antibody
  • cytochrome P450 3A4 (PTRG_06060) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (cyp3a4) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA, polypeptide 4 (CYP3A4) antibody
  • CP33 antibody
  • CP34 antibody
  • CYP3A antibody
  • CYP3A3 antibody
  • CYP3A4 antibody
  • CYP3A12 antibody
  • CYP3A21 antibody
  • CYP3A80 antibody
  • CYPIIIA3 antibody
  • CYPIIIA4 antibody
  • CYPIIIA21 antibody
  • HLP antibody
  • MGC108372 antibody
  • NF-25 antibody
  • P450C3 antibody
  • P450PCN1 antibody

Protein level used designations for CYP3A4

cytochrome P450 3A4 , cytochrome P450, family 3, subfamily A, polypeptide 4 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 , Cytochrome P450 CM3A-10 , cytochrome P450 3A21 , 1,8-cineole 2-exo-monooxygenase , P450-III, steroid inducible , albendazole monooxygenase , albendazole sulfoxidase , cytochrome P450 3A3 , cytochrome P450 HLp , cytochrome P450 NF-25 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 , cytochrome P450-PCN1 , glucocorticoid-inducible P450 , nifedipine oxidase , quinine 3-monooxygenase , taurochenodeoxycholate 6-alpha-hydroxylase , cytochrome P450 CYP3A12 , cytochrome P450 3A80

GENE ID SPECIES
6339762 Pyrenophora tritici-repentis Pt-1C-BFP
6344316 Pyrenophora tritici-repentis Pt-1C-BFP
548503 Xenopus (Silurana) tropicalis
463582 Pan troglodytes
100037189 Xenopus laevis
100294525 Equus caballus
100404344 Callithrix jacchus
100462903 Macaca mulatta
1576 Homo sapiens
479740 Canis lupus familiaris
416477 Gallus gallus
507988 Bos taurus
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