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CYP3A7 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP3A7 Proteins (5) and CYP3A7 Kits (3) and many more products for this protein.
Showing 10 out of 52 products:
Human Polyclonal CYP3A7 Primary Antibody for ELISA, WB - ABIN1535511
Gellner, Eiselt, Hustert, Arnold, Koch, Haberl, Deglmann, Burk, Buntefuss, Escher, Bishop, Koebe, Brinkmann, Klenk, Kleine, Meyer, Wojnowski: Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene. in Pharmacogenetics 2001
Show all 2 references for ABIN1535511
Cow (Bovine) Polyclonal CYP3A7 Primary Antibody for WB - ABIN2776998
Sim, Edwards, Boobis, Ingelman-Sundberg: CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele. in Pharmacogenetics and genomics 2005
These results suggest the existence of a marked inter-individual variability regarding the presence of the isoforms of CYP3A (show CYP3A4 Antibodies). In addition, since sorafenib is metabolized by CYP3A4 (show CYP3A4 Antibodies), but not by CYP3A7, an overexpression of CYP3A4 (show CYP3A4 Antibodies) may lead to an increase in the degradation of the drug and then to clinical ineffectiveness.
CYP3A7*1C influences outcome are required.
CYP3A4 (show CYP3A4 Antibodies), CYP3A7, UGT2B11 (show UGT2B4 Antibodies) and UGT2B15 (show UGT2B15 Antibodies) genes are significantly downregulated in melanosis coli.
Differences in the expression of nuclear receptors might determine the variability in CYP3A4 (show CYP3A4 Antibodies) and CYP3A7 expression observed in foetal liver.
Only CYP1A1 (show CYP1A1 Antibodies), CYP1B1 (show CYP1B1 Antibodies), CYP3A4 (show CYP3A4 Antibodies), CYP3A5 (show CYP3A5 Antibodies) and CYP3A7 expressed in lymphocytes and monocytes.
Report CYP3A7 metabolism of inhaled glucocorticoids.
Report distinctive response patterns of HIF-1alpha (show HIF1A Antibodies), CYP3A4 (show CYP3A4 Antibodies) and CYP3A7 to cobalt chloride in human fetal liver cells.
Expression and regulation of human fetal-specific CYP3A7 in mice
There were no statistically significant differences in the distribution of CYP3A7 polymorphic alleles between testicular cancer cases and controls suggesting no contribution to individual susceptibility to testicular cancer.
Recombinant CYP3A4 (show CYP3A4 Antibodies), CYP3A5 (show CYP3A5 Antibodies) and CYP3A7 metabolized R- and S-warfarin to 10- and 4'-hydroxywarfarin with efficiencies that depended on the individual enzymes.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. This gene undergoes readthrough transcription with the downstream CYP3AP1 pseudogene, resulting in an isoform with a novel C-terminus, as represented in GeneID:100861540.
cytochrome P450 3A7
, aryl hydrocarbon hydroxylase
, cytochrome P450, subfamily IIIA, polypeptide 7
, cytochrome P450-HFLA
, flavoprotein-linked monooxygenase
, microsomal monooxygenase
, xenobiotic monooxygenase