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Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) ELISA Kits

CYP51A1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 Antibodies (43) and Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CYP51A1 CYP51A1 13121 Q8K0C4
Anti-Rat CYP51A1 CYP51A1 25427 Q64654
Anti-Human CYP51A1 CYP51A1 1595 Q16850
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More ELISA Kits for Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 Interaction Partners

Mouse (Murine) Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) interaction partners

  1. Our Cyp51 LKO model shows that steatosis appears with dietary fats in the absence of dietary cholesterol and its synthesis, while a block in the cholesterol pathway leads to NASH (show SAMSN1 ELISA Kits)-like features

  2. germ cell-specific ablation of Cyp51, leading to lack of MAS (show MAS1 ELISA Kits), did not affect testicular morphology, daily sperm production, or reproductive performance in males.

  3. Cyp51 knock-out mice provide evidence that Cyp51 is essential for embryogenesis and present a potential animal model for studying ABS syndrome in humans.

  4. Findings suggest that FSH (show BRD2 ELISA Kits), partially at least, employs CYP51, and therefore the MAS (show MAS1 ELISA Kits) pathway, to initiate oocyte meiosis.

  5. localization of CYP51 in testis and ovary shows Leydig cells and acrosomes of spermatids express the highest levels

  6. Demethylation of lanosterol to FF-MAS (show MAS1 ELISA Kits) by the acrosomal lanosterol 14 alpha-demethylase enzyme complex demonstrates for the first time the ability of ejaculate sperm to synthesize meiosis-activating sterols.

  7. A gene participating in cholesterol bisynthesis (CYP51) is regulated in an immediate early (show JUN ELISA Kits) fashion, which influences sterol profile of the cell.

  8. there was a cholesterol levels link-modulation system between cholesterol synthetic pathway through CYP51 and cholesterol transport pathway through , low-density lipoprotein receptor (show LDLR ELISA Kits) in vivo

  9. These data indicate that Crem-dependent regulation of Cyp51 in the liver results in circadian expression of this gene.

  10. Lanosterol 14alpha-demethylase (show MBD2 ELISA Kits) (LDM) is closely related to mouse embryo implantation and can be upregulated by oestrogen.

Human Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) interaction partners

  1. Acyl-Carbon Bond Cleaving Cytochrome P450 (show CYP ELISA Kits) Enzymes: CYP17A1 (show CYP17A1 ELISA Kits), CYP19A1 (show CYP19A1 ELISA Kits) and CYP51A1.

  2. Suggest that GDF9 (show GDF9 ELISA Kits), possibly with FSH (show BRD2 ELISA Kits), may play significant roles in the regulation of cholesterol biosynthesis and the expression of CYP51A1 in granulosa cells which might be a predictor for unfertilization.

  3. Data show that forkhead transcription factor 4 (FoxO4) interacts with sterol regulatory element binding protein (SREBP)2 and hypoxia inducible factor (HIF)2alpha to modulate lanosterol 14alpha demethylase (CYP51) promoter activity.

  4. Our results indicate a new link between a cholesterol synthesis gene CYP51A1 and pregnancy pathologies.

  5. The studied azoles selectively interacted with human cytochrome P450 51A1, which showed the highest affinity towards ketoconazole.

  6. Low nucleotide variability of CYP51A1 is seen in cholesterol and bile acid synthesis and xenobiotic metabolism pathways.

  7. The new CYP51A1 inhibitor 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LEK-935) on the proteome of primary human hepatocytes were analyzed.

  8. A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase (show MBD2 ELISA Kits) gene.

  9. the liver X receptor alpha (show NR1H3 ELISA Kits) directly silencing the expression of two key cholesterologenic enzymes (lanosterol 14alpha-demethylase (show MBD2 ELISA Kits) (CYP51A1), and squalene synthase (farnesyl diphosphate farnesyl transferase 1 (show FDFT1 ELISA Kits))) via novel negative LXR (show NR1H3 ELISA Kits) DNA response elements

Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP51A1

  • cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1) antibody
  • cytochrome P450, family 51 (cyp51) antibody
  • cytochrome P450, family 51, subfamily A, polypeptide 1 (cyp51a1) antibody
  • cytochrome P450, family 51 (Cyp51) antibody
  • cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51) antibody
  • AI426508 antibody
  • CP51 antibody
  • CYP51 antibody
  • CYP51A1 antibody
  • CYPL1 antibody
  • CYPLI antibody
  • LDM antibody
  • P450-14DM antibody
  • P450L1 antibody
  • P450LI antibody
  • RATCP14DM antibody

Protein level used designations for CYP51A1

CYPLI , Cytochrome P450 51A1 , LDM , cytochrome P450-14DM , cytochrome P45014DM , cytochrome P450LI , lanosterol 14-alpha demethylase , sterol 14-alpha demethylase , cytochrome P450, family 51, subfamily A, polypeptide 1 , 14 alpha demethylase , lanosterol 14-demethylase , cytochrome P450 51A1 , cytochrome P450, 51 , lanosterol 14-alpha-demethylase , Cytochrom P450 Lanosterol 14 alpha-demethylase , P450-14DM , P45014DM , P450LI , cytochrome P450 Lanosterol 14 alpha-demethylase , cytochrome P450, subfamily 51 , cytochrome P450, 51 (lanosterol 14-alpha-demethylase) , cytochrome P450 51

GENE ID SPECIES
100171776 Pongo abelii
414330 Strongylocentrotus purpuratus
420548 Gallus gallus
463527 Pan troglodytes
548948 Xenopus (Silurana) tropicalis
100037098 Xenopus laevis
13121 Mus musculus
25427 Rattus norvegicus
1595 Homo sapiens
505060 Bos taurus
403334 Sus scrofa
475225 Canis lupus familiaris
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