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Cytohesin 2 (CYTH2) ELISA Kits

The protein encoded by CYTH2 is a member of the PSCD family. Additionally we are shipping Cytohesin 2 Antibodies (76) and Cytohesin 2 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYTH2 9266 Q99418
Anti-Rat CYTH2 CYTH2 116692 P63035
Anti-Mouse CYTH2 CYTH2 19158 P63034
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Top Cytohesin 2 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 2.34 pg/ml 9.375-600 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for Cytohesin 2 Interaction Partners

Human Cytohesin 2 (CYTH2) interaction partners

  1. Data establish a role for cytohesin-2/ARNO as a regulator of R-Ras and integrin recycling and suggest that ARF-regulated trafficking of R-Ras is required for R-Ras-dependent effects on spreading and adhesion formation.

  2. The authors show that Shigella flexneri IpgD phosphatase activity is required for recruitment of the ARF6 (show ARF6 ELISA Kits) guanine nucleotide exchange factor (show RASGRF1 ELISA Kits) (GEF) ARF nucleotide binding site opener (ARNO) to bacterial entry sites.

  3. inhibiting cytohesins or ARNO as cytoplasmic activators of EGFR (show EGFR ELISA Kits) and IGF-I (show IGF1 ELISA Kits) in colorectal cancer resulted in anti-proliferation, reduced invasion, decreased migration, and suppressed growth in vivo and in vitro.

  4. Cytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 (show ARF6 ELISA Kits) in a GTP (show AK3 ELISA Kits)-bound state

  5. Expression of CYTH2 mutant deficient of the EFh2 domain in cells also inhibits Arf6 (show ARF6 ELISA Kits) activation and neurite extension.

  6. Phosphorylation of Ser392 of ARNO stabilized the C-terminal alpha-helix via formation of salt bridges between phospho-Ser392 and Arg390, Lys395, and Lys396.

  7. There is an association between cytohesin-2 expression and overall survival and disease-free survival in patients with hepatocellular carcinoma.

  8. Arf6 (show ARF6 ELISA Kits)/ ARNO signaling mediates phospholipase-D (show PLD ELISA Kits), ERK1/2 (show MAPK1/3 ELISA Kits) and cofilin (show CFL1 ELISA Kits) activation in pancreatic beta-cells.

  9. Kinetics of interaction between ADP-ribosylation factor-1 (Arf1 (show ARF1 ELISA Kits)) and the Sec7 (show CYTH1 ELISA Kits) domain of Arno guanine nucleotide exchange factor (show RASGRF1 ELISA Kits), modulation by allosteric factors, and the uncompetitive inhibitor brefeldin A

  10. The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (show ATP6V1B2 ELISA Kits) (V-ATPase (show DNAH8 ELISA Kits)) and cytohesin-2

Mouse (Murine) Cytohesin 2 (CYTH2) interaction partners

  1. The RLIP76 (show RALBP1 ELISA Kits)/R-Ras/ARNO complex localizes to recycling endosomes.

  2. signaling through cytohesin-2 is required for myelination by Schwann cells, and cytohesin-2 is added to the list of molecules known to underlie PNS myelination

  3. results together suggest that cytohesin 2 activates ARF6 (show ARF6 ELISA Kits) in a PI3K dependent manner and then the active ARF6 (show ARF6 ELISA Kits) causes phosphorylation of ERK1/2 (show MAPK1/3 ELISA Kits) during preadipocyte migration.

  4. Cytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 (show ARF6 ELISA Kits) in a GTP (show AK3 ELISA Kits)-bound state

  5. Expression of CYTH2 mutant deficient of the EFh2 domain in cells also inhibits Arf6 (show ARF6 ELISA Kits) activation and neurite extension.

  6. The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (show ATP6V1B2 ELISA Kits) (V-ATPase (show DNAH8 ELISA Kits)) and cytohesin-2

  7. role for endothelial ARNO in VEGF (show VEGFA ELISA Kits)-dependent initiation of angiogenesis by regulation of VEGFR-2 (show KDR ELISA Kits) internalization in endothelial cells, resulting in the activation of the Akt (show AKT1 ELISA Kits) pathway, vessel permeability, and ultimately endothelial proliferation

  8. cytohesin-2, through a previously unexplored complex formation with paxillin (show PXN ELISA Kits), regulates preadipocyte migration; paxillin (show PXN ELISA Kits) plays a previously unknown role as a scaffold protein (show HOMER1 ELISA Kits) of Arf guanine-nucleotide exchange factor (show ARHGEF12 ELISA Kits)

  9. Specific motifs of the V-ATPase a2 (show ATP6V0A2 ELISA Kits)-subunit isoform interact with catalytic and regulatory domains of ARNO.

  10. Arl4D (show ARL4D ELISA Kits) is a previously unknown regulator of neurite formation through cytohesin-2 and Arf6 (show ARF6 ELISA Kits), providing another example that the functional interaction of two different small GTPases controls an important cellular function.

Cytohesin 2 (CYTH2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Cytohesin 2 (CYTH2) ELISA Kits

  • cytohesin-2 (PTRG_08834) antibody
  • cytohesin 2 (cyth2) antibody
  • cytohesin 2 (CYTH2) antibody
  • pleckstrin homology, Sec7 and coiled-coil domains 2 (pscd2) antibody
  • cytohesin 2 (Cyth2) antibody
  • Arno antibody
  • CLM2 antibody
  • CTS18 antibody
  • CTS18.1 antibody
  • CYTH2 antibody
  • MGC80440 antibody
  • MGC84366 antibody
  • Pscd2 antibody
  • PSCD2L antibody
  • Sec7 antibody
  • Sec7B antibody
  • SEC7L antibody
  • Sec7p-L antibody
  • Sec7p-like antibody

Protein level used designations for Cytohesin 2 (CYTH2) ELISA Kits

cytohesin-2 , cytohesin 2 , pleckstrin homology, Sec7 and coiled/coil domains 2 , pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2) , cytohesin-2-like , ARF exchange factor , ARF nucleotide-binding site opener , PH, SEC7 and coiled-coil domain-containing protein 2 , pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2) , ARF nucleotide binding site opener , CLM2 , SEC7 homolog B , pleckstrin homology, Sec7 and coiled-coil domains 2 , mSec7-2

GENE ID SPECIES
6347120 Pyrenophora tritici-repentis Pt-1C-BFP
444689 Xenopus laevis
448569 Xenopus (Silurana) tropicalis
718682 Macaca mulatta
746757 Pan troglodytes
779436 Xenopus laevis
100216436 Ovis aries
100387102 Callithrix jacchus
100440057 Pongo abelii
9266 Homo sapiens
116692 Rattus norvegicus
19158 Mus musculus
476423 Canis lupus familiaris
768035 Bos taurus
100240721 Sus scrofa
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