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CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Additionally we are shipping Cytokine Induced Apoptosis Inhibitor 1 Proteins (12) and many more products for this protein.
Showing 10 out of 72 products:
Human Polyclonal CIAPIN1 Primary Antibody for IHC, IHC (p) - ABIN4298735
Nymoen, Holth, Hetland Falkenthal, Tropé, Davidson: CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma. in Molecular cancer 2015
Show all 2 Pubmed References
Human Polyclonal CIAPIN1 Primary Antibody for ICC, IF - ABIN4298734
Ferecatu, Gonçalves, Golinelli-Cohen, Clémancey, Martelli, Riquier, Guittet, Latour, Puccio, Drapier, Lescop, Bouton: The diabetes drug target MitoNEET governs a novel trafficking pathway to rebuild an Fe-S cluster into cytosolic aconitase/iron regulatory protein 1. in The Journal of biological chemistry 2014
the effects of CIAPIN-1 in chondrocytes, focusing on extracellular signal-regulated kinase (ERK)-1 (show MAPK3 Antibodies)/2 and p38 (show CRK Antibodies) kinase signaling
results of the present study suggest that downregulation of the CIAPIN1 gene in multiple myeloma cells may be associated with the development of this disease.
CIAPIN1 and ABCA13 (show ABCA13 Antibodies) may be novel markers of poor outcome in pre-chemotherapy serous carcinoma effusions.
CIAPIN1 over-expression decreases NHE1 (show SLC9A1 Antibodies) expression and ERK1/2 (show MAPK1/3 Antibodies) phosphorylation.
lentivirus-vector-mediated RNAi targeting of CIAPIN1 is a potential approach to reverse MDR of breast cancer and CIAPIN1 may participate in MDR of breast cancer by regulating P-glycoprotein and P53 (show TP53 Antibodies) expression.
the 25-kDa cleaved fragment of anamorsin was detected in post-mortem brains of Alzheimer and Parkinson (show CASP3 Antibodies) disease patients
The N-terminal methyltransferase-like domain of anamorsin probably functions as a structural scaffold to inhibit methyl transfers.
CIAPIN1 targeted NHE1 (show SLC9A1 Antibodies) to mediate differentiation of K562 cells via ERK1/2 (show MAPK1/3 Antibodies) pathway.
Mossbauer and EPR (show EREG Antibodies) spectra of human anamorsin show that both the M1 motif and the M2 motif bind independently a [2Fe-2S] cluster through the four cysteines of each motif.
CIAPIN1 siRNA inhibited proliferation, migration and promotes apoptosis of vascular smooth muscle cells by regulating Bcl-2 (show BCL2 Antibodies) and Bax (show BAX Antibodies).
Among 46 putative substrates identified in MN9D neuronal cells, we further evaluated whether caspase-3 (show CASP3 Antibodies)-mediated cleavage of anamorsin, a recently recognized cell death-defying factor in hematopoiesis, is a general feature of apoptosis.
These data suggest that PKCtheta;, PKCdelta, and p38MAPK activation lead to cell cycle retardation in AM KO MEF cells, and that AM may negatively regulate novel PKCs and p38MAPK in MEF cells.
Anamorsin is considered to be a necessary molecule for hematopoiesis that mediates antiapoptotic effects of various cytokines.
CIAPIN1 was localized in both the cytoplasm and the nucleus and was accumulated in the nucleolus. Bioinformatic prediction disclosed a putative nuclear localization signal and a putative nuclear export signal within mouse CIAPIN1.
CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004
, cytokine-induced apoptosis inhibitor 1
, fe-S cluster assembly protein DRE2 homolog
, cytokine induced apoptosis inhibitor 1
, Fe-S cluster assembly protein DRE2 homolog
, Cytokine-induced apoptosis inhibitor 1
, predicted protein of HQ0915