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Cytokine Receptor-Like Factor 1 Proteins (CRLF1)

CRLF1 encodes a member of the cytokine type I receptor family. Additionally we are shipping Cytokine Receptor-Like Factor 1 Antibodies (50) and Cytokine Receptor-Like Factor 1 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CRLF1 9244 O75462
CRLF1 12931 Q9JM58
Rat CRLF1 CRLF1 290655  
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Top Cytokine Receptor-Like Factor 1 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

CRLF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Cytokine Receptor-Like Factor 1 (CRLF1) Interaction Partners

Human Cytokine Receptor-Like Factor 1 (CRLF1) interaction partners

  1. CLF-1, based on its binding site for CLC (show CLC Proteins) and on two additional and independent sites for CNTFRalpha (show CNTFR Proteins) and sorLA (show SORL1 Proteins), is a key player in CLC (show CLC Proteins) and CNTFRalpha (show CNTFR Proteins) signaling and turnover.

  2. Article reports 11 novel mutations in CRLF1 expanding the mutational spectrum of CRLF1 in the Crisponi/cold-induced sweating type 1 syndrome to a total of 35 variants.

  3. The mutation detected in CRLF1 has not been described in patients with CISS1, but in one with CS. These data seem to support the theory that CS and CISS1 are variants of the same disorder.

  4. Data indicate that CRLF1 serves its protective role by a cell autonomous mechanism that is independent of the gp130 (show IL6ST Proteins)/JAK (show JAK3 Proteins) signaling pathway.

  5. In idiopathic pulmonary fibrosis, CLF-1 is a selective stimulus of type II alveolar epithelial cells and may potentially drive an antifibrotic response by augmenting both T-helper-1-driven and T-regulatory-cell-driven inflammatory responses in the lung.

  6. CRLF1 mutations showed that phenotypic severity of the two disorders: Crisponi syndrome (CS) and cold-induced sweating syndrome type 1 (CISS1) mainly depends on altered kinetics of secretion of the mutated CRLF1 protein.

  7. Our data suggest that the CRLF1/CLC (show CLC Proteins) complex disrupts cartilage homeostasis and promotes the progress of OA by enhancing the proliferation of chondrocytes and suppressing the production of cartilage matrix

Mouse (Murine) Cytokine Receptor-Like Factor 1 (CRLF1) interaction partners

  1. The p28 (show GSTO1 Proteins)/cytokine-like factor 1 (CLF) complex may participate in the regulation of natural killer (NK) and T cell functions by dendritic cells.

Cytokine Receptor-Like Factor 1 (CRLF1) Protein Profile

Protein Summary

This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.

Gene names and symbols associated with CRLF1

  • cytokine receptor-like factor 1 (CRLF1)
  • cytokine receptor-like factor 1 (Crlf1)
  • cytokine receptor-like factor 1a (crlf1a)
  • CISS protein
  • CISS1 protein
  • CLF protein
  • CLF-1 protein
  • clf-1.a protein
  • CRLF1 protein
  • CRLM3 protein
  • NR6 protein
  • NR6.1 protein
  • wu:fd24a10 protein
  • zcytor5 protein
  • zgc:91992 protein

Protein level used designations for CRLF1

cytokine receptor-like factor 1 , class I cytokine receptor , cytokine type 1 receptor CRLP-1 , cytokine-like factor 1 , CRLM-3 , NR6 , cytokine receptor like molecule 3 , cytokine receptor-like molecule 3 , novel cytokine receptor 6 , clf-1a , crlf1 , fd24a10

GENE ID SPECIES
720247 Macaca mulatta
735722 Pan troglodytes
9244 Homo sapiens
12931 Mus musculus
290655 Rattus norvegicus
100858730 Gallus gallus
484818 Canis lupus familiaris
100738750 Sus scrofa
511086 Bos taurus
436923 Danio rerio
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