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Cytokine-Dependent Hematopoietic Cell Linker Proteins (CLNK)

MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603\; BLNK, MIM 604515). Additionally we are shipping Cytokine-Dependent Hematopoietic Cell Linker Antibodies (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CLNK 116449 Q7Z7G1
CLNK 27278 Q9QZE2
Rat CLNK CLNK 295518  
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Top Cytokine-Dependent Hematopoietic Cell Linker Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CLNK Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Cytokine-Dependent Hematopoietic Cell Linker (CLNK) Interaction Partners

Human Cytokine-Dependent Hematopoietic Cell Linker (CLNK) interaction partners

  1. CLNK and ZNF518B SNPs may have potential as diagnostic and prognostic marker for Chinese gout patients.

Mouse (Murine) Cytokine-Dependent Hematopoietic Cell Linker (CLNK) interaction partners

  1. Clnk is required for TNF-alpha (show TNF Proteins) -induced cell death in L929 cells.

  2. Clnk is dispensable for normal differentiation and function of T cells, mast cells, and NK cells. Hence, unlike its relatives, Clnk is not essential for normal immune functions

  3. STAT5 (show STAT5A Proteins) is involved in cytokine-mediated up-regulation of MIST gene expression, in collaboration with other lineage-specific transcription factors that promote basal MIST expression in mast cells.

  4. interaction of MIST with Fgr (show FGR Proteins), mediated by the C-terminal proline-rich region of MIST and the SH3 domain of Fgr (show FGR Proteins), was required for the suppression of NK-cell receptor (show KLRD1 Proteins)-induced IFN-gamma (show IFNG Proteins) production

Cytokine-Dependent Hematopoietic Cell Linker (CLNK) Protein Profile

Protein Summary

MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603\; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1\; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999

Gene names and symbols associated with CLNK

  • cytokine-dependent hematopoietic cell linker (CLNK)
  • cytokine-dependent hematopoietic cell linker (Clnk)
  • Mist protein
  • RGD1562417 protein

Protein level used designations for CLNK

mast cell immunoreceptor signal transducer

GENE ID SPECIES
116449 Homo sapiens
27278 Mus musculus
295518 Rattus norvegicus
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