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MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603\\\\; BLNK, MIM 604515). Additionally we are shipping Cytokine-Dependent Hematopoietic Cell Linker Proteins (4) and many more products for this protein.
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Human Polyclonal CLNK Primary Antibody for WB - ABIN657864
Goitsuka, Tatsuno, Ishiai, Kurosaki, Kitamura: MIST functions through distinct domains in immunoreceptor signaling in the presence and absence of LAT. in The Journal of biological chemistry 2001
Show all 4 references for ABIN657864
Identify positive correlations between WDR1 (show WDR1 Antibodies) and CLNK gene polymorphisms in Chinese-Tibetan gout populations.
CLNK and ZNF518B SNPs may have potential as diagnostic and prognostic marker for Chinese gout patients.
Clnk is required for TNF-alpha (show TNF Antibodies) -induced cell death in L929 cells.
Clnk is dispensable for normal differentiation and function of T cells, mast cells, and NK cells. Hence, unlike its relatives, Clnk is not essential for normal immune functions
STAT5 (show STAT5A Antibodies) is involved in cytokine-mediated up-regulation of MIST gene expression, in collaboration with other lineage-specific transcription factors that promote basal MIST expression in mast cells.
interaction of MIST with Fgr (show FGR Antibodies), mediated by the C-terminal proline-rich region of MIST and the SH3 domain (show ITSN1 Antibodies) of Fgr (show FGR Antibodies), was required for the suppression of NK-cell receptor (show KLRD1 Antibodies)-induced IFN-gamma (show IFNG Antibodies) production
MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603\; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1\; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999
mast cell immunoreceptor signal transducer