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Cytoskeleton Associated Protein 2 (CKAP2) ELISA Kits

CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007. Additionally we are shipping Cytoskeleton Associated Protein 2 Antibodies (29) and Cytoskeleton Associated Protein 2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CKAP2 CKAP2 26586 Q8WWK9
Anti-Mouse CKAP2 CKAP2 80986 Q3V1H1
Anti-Rat CKAP2 CKAP2 306575  
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More ELISA Kits for Cytoskeleton Associated Protein 2 Interaction Partners

Human Cytoskeleton Associated Protein 2 (CKAP2) interaction partners

  1. Chromatin CKAP2 is an independent prognostic marker for relapse-free survival in early-stage breast cancer, and could potentially replace the mitotic activity index in clinical evaluation of proliferation activity.

  2. The transcriptional activity of RHOA (show RHOA ELISA Kits), SEMA3B (show SEMA3B ELISA Kits), and CKAP2 genes was assessed in blood samples of leukaemia patients and healthy donors.

  3. CKAP2 is involved in the maintenance of microtubule nucleation sites

  4. GC box was responsible for the cyclic activity of human CKAP2 promoter through the phosphorylation of Sp1 (show PSG1 ELISA Kits), possibly by Cyclin A (show CCNA2 ELISA Kits)/Cdk (show CDK4 ELISA Kits) complex.

  5. Findings suggest that the motif surrounding Ser627 ((625) RRSRRL (630)) is a critical for kinase-substrate recognition and for regulation of the subcellular localization of TMAP during mitosis.

  6. TMAP is limited to pre-anaphase stages and suggest that the multiple phosphorylation may not act in concert but serve diverse functions.

  7. CKAP2 comprises nine exons ranging 70-1442 bp and is about 22 kb in size (regulatory regions included). The CKAP2 promoter contains CCAAT (-39...-33) rather than the canonical TATA box, and harbors nine binding sites for six transcription factors

  8. Data show that degradation of TMAP/CKAP2 during mitotic exit is mediated by the anaphase-promoting complex bound to Cdh1 (show CDH1 ELISA Kits) and that the KEN (show PCNT ELISA Kits) box motif near the N terminus is necessary for its destruction.

  9. CKAP2 is a physiological substrate of anaphase-promoting complex (show CDC26 ELISA Kits)/cyclosome during mitotic exit and that a tight regulation of the CKAP2 protein level is critical for the normal mitotic progression.

  10. Cdk1 (show CDK1 ELISA Kits)-cyclin B1 (show CCNB1 ELISA Kits)-mediated phosphorylation of TMAP is important for and contributes to proper regulation of microtubule dynamics and establishment of functional bipolar spindles during mitosis

Mouse (Murine) Cytoskeleton Associated Protein 2 (CKAP2) interaction partners

  1. These findings suggest that CKAP2 is a new MAP with microtubule-stabilizing properties

  2. Data suggest the existence of a functional positive feedback loop in which Ckap2 activates the G1 tetraploidy checkpoint and prevents aneuploidy.

  3. The cellular functions of TMAP/CKAP2 might be regulated by timely phosphorylation and dephosphorylation during the course of mitosis.

  4. Our present findings demonstrate that TMAP/CKAP2 is essential for proper chromosome segregation and for maintaining genomic stability.

Cytoskeleton Associated Protein 2 (CKAP2) Antigen Profile

Antigen Summary

CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007

Gene names and symbols associated with CKAP2

  • cytoskeleton associated protein 2 (CKAP2) antibody
  • cytoskeleton associated protein 2 (Ckap2) antibody
  • AI461656 antibody
  • AW228814 antibody
  • LB1 antibody
  • se20-10 antibody
  • TMAP antibody

Protein level used designations for CKAP2

cytoskeleton-associated protein 2 , intracellular protein , cytoskeleton associated protein 2 , cytoskeleton-associated protein 2-like , CTCL tumor antigen se20-10 , tumor- and microtubule-associated protein , tumor-associated microtubule-associated protein

GENE ID SPECIES
100052303 Equus caballus
418882 Gallus gallus
100515274 Sus scrofa
26586 Homo sapiens
80986 Mus musculus
306575 Rattus norvegicus
515249 Bos taurus
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