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Cytoskeleton Associated Protein 5 (CKAP5) ELISA Kits

CKAP5 encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. Additionally we are shipping CKAP5 Antibodies (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CKAP5 CKAP5 9793 Q14008
Anti-Mouse CKAP5 CKAP5 75786 A2AGT5
Anti-Rat CKAP5 CKAP5 311191  
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More ELISA Kits for CKAP5 Interaction Partners

Xenopus laevis Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

  1. Results show that XMAP215 can be used as a handle to sense and mechanically manipulate the dynamics of the microtubule tip.

  2. XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules.

Human Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

  1. Eribulin binding to the tip of microtubules and subsequent loss of ch-TOG is a priming event leading to alterations in microtubule dynamics and breast cancer cell migration.

  2. Data show that cytoskeleton associated protein 5 (chTOG) only weakly promotes importin (show KPNA4 ELISA Kits)-regulated microtubule nucleation, but acts synergistically with microtubule- associated protein TPX2 (show TPX2 ELISA Kits).

  3. Aurora-A kinase (show AURKA ELISA Kits) does not regulate TACC3 (show TACC3 ELISA Kits)-chTOG complex formation, indicating that Aurora-A (show AURKA ELISA Kits) solely functions as a recruitment factor for the TACC3 (show TACC3 ELISA Kits)-chTOG complex to centrosomes and proximal mitotic spindles.

  4. Data show that five genes CKAP5, KPNB1 (show KPNB1 ELISA Kits), RAN, TPX2 (show TPX2 ELISA Kits) and KIF11 (show KIF11 ELISA Kits) were shown to be essential for tumor cell survival in both head and neck squamous cell carcinoma (HNSCC)and non-small cell lung cancer (NSCLC), but most particularly in HNSCC.

  5. These observations indicate that EB1 (show MAPRE2 ELISA Kits) and ch-TOG regulate microtubule organisation differently via distinct regions in the plus ends of microtubules.

  6. Clathrin promotes centrosome maturation by stabilizing the microtubule-binding protein ch-TOG, defining a novel role for the clathrin-ch-TOG complex.

  7. Data show that ILK (show ILK ELISA Kits) performs its centrosome clustering activity in a centrosome-dependent, manner through the microtubule regulating proteins TACC3 (show TACC3 ELISA Kits) and ch-TOG.

  8. the association between aurora A (show AURKA ELISA Kits) phosphorylation and spindle apparatus; regulation from aurora A (show AURKA ELISA Kits) is mediated by CHC (show CLTC ELISA Kits) in recruiting phospho-TACC3 (show TACC3 ELISA Kits) and subsequently ch-TOG to mitotic spindles.

  9. Data show that 4-oxo-4-HPR (show HPR ELISA Kits) inhibited tubulin (show TUBB ELISA Kits) polymerization and modulated gene expression of spindle aberration associated genes Kif 1C, Kif 2A, Eg5 (show KIF11 ELISA Kits), Tara (show TRIOBP ELISA Kits), tankyrase-1 (show TNKS ELISA Kits), centractin (show ACTR1A ELISA Kits), and TOGp.

  10. Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells

Mouse (Murine) Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

  1. in hippocampal neurons TOG is required for granule assembly, granule translation and synaptic plasticity, and affects behavior

  2. Aurora-A kinase (show AURKA ELISA Kits) does not regulate TACC3 (show TACC3 ELISA Kits)-chTOG complex formation, indicating that Aurora-A (show AURKA ELISA Kits) solely functions as a recruitment factor for the TACC3 (show TACC3 ELISA Kits)-chTOG complex to centrosomes and proximal mitotic spindles.

  3. ch-TOG promotes axonal development and is expressed in brain throughout development.

CKAP5 Antigen Profile

Antigen Summary

This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation\; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with CKAP5

  • cytoskeleton associated protein 5 (ckap5) antibody
  • cytoskeleton associated protein 5 (ckap5-a) antibody
  • cytoskeleton associated protein 5 (CKAP5) antibody
  • cytoskeleton associated protein 5 (Ckap5) antibody
  • 3110043H24Rik antibody
  • 4930432B04Rik antibody
  • ch-TOG antibody
  • CHTOG antibody
  • CKAP5 antibody
  • ckap5b antibody
  • D730027C18Rik antibody
  • im:7143385 antibody
  • mKIAA0097 antibody
  • MSPS antibody
  • T25636 antibody
  • TOG antibody
  • TOGp antibody
  • wu:fb14c01 antibody
  • wu:fb59e03 antibody
  • wu:fi33f02 antibody
  • xmap215 antibody
  • zgc:123012 antibody

Protein level used designations for CKAP5

cytoskeleton associated protein 5 , microtubule associated protein XMAP215 , cytoskeleton-associated protein 5 , microtubule-associated protein 215 , colonic and hepatic tumor over-expressed protein , Cytoskeleton-associated protein 5 , cytoskeleton-associated protein 5-like , colonic and hepatic tumor over-expressed gene protein , colonic and hepatic tumor overexpressed gene protein

GENE ID SPECIES
398198 Xenopus laevis
398199 Xenopus laevis
423190 Gallus gallus
451160 Pan troglodytes
492614 Danio rerio
533980 Bos taurus
100011933 Monodelphis domestica
100050886 Equus caballus
100145713 Xenopus (Silurana) tropicalis
100379262 Anolis carolinensis
100379285 Gasterosteus aculeatus
100380854 Salmo salar
100473125 Ailuropoda melanoleuca
100548902 Meleagris gallopavo
9793 Homo sapiens
75786 Mus musculus
311191 Rattus norvegicus
100351133 Oryctolagus cuniculus
475986 Canis lupus familiaris
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