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Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Additionally we are shipping CIAO1 Proteins (18) and CIAO1 Kits (4) and many more products for this protein.
Showing 10 out of 64 products:
Cow (Bovine) Polyclonal CIAO1 Primary Antibody for IHC, WB - ABIN2775776
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
Data suggest that CIA2B and MMS19 (show MMS19 Antibodies) physically interact with C-terminus of viperin/RSAD2 (show RSAD2 Antibodies); CIAO1 appears to function as primary viperin (show RSAD2 Antibodies)-interacting protein; CIA2A binds to N-terminus of viperin (show RSAD2 Antibodies) in CIAO1-, CIA2B-, and MMS19 (show MMS19 Antibodies)-independent fashion. (CIA2B = metallochaperone CIA2B/FAM96B (show FAM96B Antibodies); MMS19 (show MMS19 Antibodies) = transcription factor MMS19 (show MMS19 Antibodies); CIAO1 = cytosolic iron-sulfur assembly component 1; CIA2A = metallochaperone CIA2A/Fam96a (show FAM96A Antibodies))
POLE1 (show POLE Antibodies) is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19 (show MMS19 Antibodies).
These data suggest that viperin (show RSAD2 Antibodies) requires CIAO1 for [4Fe-4S] cluster assembly, and acts through an enzymatic, Fe-S cluster- and SAM (show TTN Antibodies)-dependent mechanism to inhibit viral RNA synthesis.
CIA2B-CIA1-MMS19 (show MMS19 Antibodies) and CIA2A-CIA1 assist different branches of Fe/S protein (show CDSN Antibodies) assembly and intimately link this process to cellular iron regulation via IRP1 (show ACO1 Antibodies) Fe/S cluster maturation and IRP2 (show IREB2 Antibodies) stabilization.
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
, WD40 protein Ciao1
, cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)
, cytosolic iron-sulfur protein assembly 1
, probable cytosolic iron-sulfur protein assembly protein CIAO1-like
, WD repeat domain 39
, WD repeat-containing protein 39
, cytosolic iron-sulfur protein assembly 1 homolog
, probable cytosolic iron-sulfur protein assembly protein CIAO1
, probable cytosolic iron-sulfur protein assembly protein ciao1