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Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) ELISA Kits

CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. Additionally we are shipping CTLA4 Antibodies (455) and CTLA4 Proteins (69) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CTLA4 12477 P09793
CTLA4 1493 P16410
CTLA4 63835  
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Top CTLA4 ELISA Kits at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 10pg/mL 156-10000 pg/mL Mouse CTLA4 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$369.00
Details
Human 12.4 pg/mL 31.2-2000 pg/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Rat 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 8 to 9 Days
$638.00
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Rabbit 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Guinea Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Monkey
  96 Tests Log in to see 11 to 13 Days
$832.86
Details
Sheep
  96 Tests Log in to see 11 to 13 Days
$832.86
Details
Dog
  96 Tests Log in to see 11 to 13 Days
$801.43
Details

Top referenced CTLA4 ELISA Kits

  1. Mouse (Murine) CTLA4 ELISA Kit for Sandwich ELISA - ABIN1672780 : Dariavach, Mattéi, Golstein, Lefranc: Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains. in European journal of immunology 1989 (PubMed)

More ELISA Kits for CTLA4 Interaction Partners

Mouse (Murine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Data suggest enhanced clinical benefit from combining CTLA-4 antigen blockade with poxvirus-based active immunotherapy.

  2. up-regulated expression correlates with the tolerogenic effect of syngeneic hematopoietic stem cell transplantation

  3. Induced Treg Cells Augment the Th17-Mediated Intestinal Inflammatory Response in a CTLA4-Dependent Manner

  4. CTLA-4 has a regulatory T cell-intrinsic role in limiting peripheral regulatory T cell expansion and activation, and in their capacity to control conventional T cells.

  5. The Ctla4 SNP (e2_77A/G) does not alter diabetes susceptibility, but does control mRNA alternative splicing.

  6. Sorafenib suppressed the expression of immunosuppressive factors in MDSCs. These data indicate that combination therapy of sorafenib and anti-CTLA-4 Ab may be effective in advanced kidney cancer patients.

  7. The co-stimulatory molecule CTLA-4 mediates in vitro differentiation of iTreg cells.

  8. The bullseye immunological synapse formation is mediated by CTLA4, and may negatively control T-cell activation as a suppressive synapse.

  9. this study reports that regulatory T (Treg) cells orchestrate memory T cell quiescence by suppressing effector and proliferation programs through inhibitory receptor, cytotoxic- T-lymphocyte-associated protein-4 (CTLA-4).

  10. Short-term blockade with anti-CTLA-4 antibody in wild-type mice is sufficient to elicit follicular helper T cell generation and germinal center development. The latter occurs in a CD28 (show CD28 ELISA Kits)-dependent manner.

Human Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. It failed to show any association between CTLA-4 -318C/T polymorphism and the risk of malignant bone tumors.

  2. this study shows that CTLA-4 expression in the naive Treg is decreased in preterm newborns

  3. No significant association was found between +49A/G (rs231775), -318C/T (rs5742909), and +6230A/G (rs3087243) CTLA-4 gene polymorphisms and lymphoid malignancies.

  4. Studies suggest that the cytotoxic T lymphocyte associated protein 4 (CTLA4) polymorphisms of the three alleles are not associated with genetic susceptibility to non-Hodgkin's lymphoma (NHL (show RTEL1 ELISA Kits)) risk.

  5. Immune surveillance is an important mechanism in prevention of cancer development and inhibition of growth of tumors and metastasis. Checkpoint pathways prevent immune response through multiple methods including CTLA-4 and PD-1 (show PDCD1 ELISA Kits)/PD-L1 (show CD274 ELISA Kits) pathways.A variety of immune checkpoint inhibitors (PD-1 (show PDCD1 ELISA Kits)/PD-L1 (show CD274 ELISA Kits) and CTLA-4 inhibitors) have been studied in recurrent and metastatic head and neck cancers with encouraging efficacy

  6. n combination with anti-PD-1 (show PDCD1 ELISA Kits)/PD-L1 (show CD274 ELISA Kits), the CTLA-4-expanded T cells are prevented from being functionally inhibited when they enter into the tumor microenvironment.

  7. The CTLA-4 receptor was one of the first checkpoint inhibitors to be targeted with limited exploration and efficacy in sarcoma.The PD-1 (show PDCD1 ELISA Kits)/PD-L1 (show CD274 ELISA Kits) immunologic checkpoint pathway has demonstrated efficacy in many malignancies; studies are ongoing in sarcoma.

  8. We present multiplexed RO assays for an IGF1R (show IGF1R ELISA Kits)-EGFR (show EGFR ELISA Kits) bispecific antibody (Bs-Ab) and a CTLA4-Ig recombinant fusion protein to demonstrate key considerations for accurate RO assessment.

  9. PD-1 (show PDCD1 ELISA Kits) and CTLA-4 expression during the symptomatic phase was significantly higher in the T-cells of Acute Hepatitis A patients than in those of Acute Toxic Hepatitis patients or healthy controls.

  10. anti-CTLA-4 and anti-PD-1 (show PDCD1 ELISA Kits) immune checkpoint blockade (ICB) monoclonal antibodies are becoming parts of the oncologists' armamentarium against melanoma and non small-cell lung cancer (NSCLC).

Pig (Porcine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Suggest a truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin as a novel approach for in vivo depletion of CD80 (show CD80 ELISA Kits)-positive cells.

Cow (Bovine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. The surface expression of CTLA-4 was increased in subclinical stages of paratuberculosis infection while levels of ZAP-70 (show ZAP70 ELISA Kits) were decreased in CD4 (show CD4 ELISA Kits)+ T cells of both subclinical and clinical animals, indicating a change in T cell phenotype with disease state.

  2. These results suggested that the expression level of CTLA-4 in CD4 (show CD4 ELISA Kits)-positive T cells has a potentially immunosuppressive function in bovine leukemia infection.

  3. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 (show FOXP3 ELISA Kits) and CTLA4.

CTLA4 Antigen Profile

Antigen Summary

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Gene names and symbols associated with CTLA4

  • cytotoxic T-lymphocyte-associated protein 4 precursor (CTLA-4) antibody
  • cytotoxic T-lymphocyte-associated protein 4 (CTLA4) antibody
  • cytotoxic T-lymphocyte-associated protein 4 (LOC100222727) antibody
  • cytotoxic T-lymphocyte-associated protein 4 (Ctla4) antibody
  • CD antibody
  • Cd152 antibody
  • CELIAC3 antibody
  • Ctla-4 antibody
  • CTLA4 antibody
  • GRD4 antibody
  • GSE antibody
  • IDDM12 antibody
  • Ly-56 antibody
  • sCTLA4 antibody

Protein level used designations for CTLA4

cytotoxic T-lymphocyte-associated protein 4 precursor , CD152 protein , cytotoxic T-lymphocyte protein 4 , cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM , cytotoxic T-lymphocyte-associated protein 4 , costimulatory molecule B7 receptor , cytotoxic T lymphocyte-associated antigen 4 , CD152 antigen , cytotoxic T-lymphocyte-associated antigen 4 , CD152 isoform , celiac disease 3 , cytotoxic T lymphocyte associated antigen 4 short spliced form , cytotoxic T-lymphocyte antigen 4 , cytotoxic T-lymphocyte-associated serine esterase-4 , ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 , soluble form , transmembrane form , CTLA-4 , cytotoxic T lymphocyte-associated protein 4 , costimulatory molecule B7 receptor CD152

GENE ID SPECIES
443040 Ovis aries
705673 Macaca mulatta
100222727 Taeniopygia guttata
424106 Gallus gallus
470619 Pan troglodytes
493743 Felis catus
100126716 Papio anubis
12477 Mus musculus
1493 Homo sapiens
63835 Rattus norvegicus
100009412 Oryctolagus cuniculus
397286 Sus scrofa
403696 Canis lupus familiaris
281732 Bos taurus
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