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D-2-Hydroxyglutarate Dehydrogenase (D2HGDH) ELISA Kits

D2HGDH encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. Additionally we are shipping D2HGDH Antibodies (14) and D2HGDH Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse D2HGDH D2HGDH 98314 Q8CIM3
Anti-Rat D2HGDH D2HGDH 301624  
D2HGDH 728294 Q8N465
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Top D2HGDH ELISA Kits at

Showing 1 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days

Top referenced D2HGDH ELISA Kits

  1. Human D2HGDH ELISA Kit - ABIN423901 : Gelman, Mahieu, Cho, Llufrio, Wencewicz, Patti: Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal carcinoma cells. in Cancer & metabolism 2015 (PubMed)

More ELISA Kits for D2HGDH Interaction Partners

Human D-2-Hydroxyglutarate Dehydrogenase (D2HGDH) interaction partners

  1. D2HGDH elevates alpha-KG levels via IDH2 (show IDH2 ELISA Kits) expression modulation, influencing histone and DNA methylation (show HELLS ELISA Kits), and HIF1alpha (show HIF1A ELISA Kits) hydroxylation. D2HGDH mutants found in diffuse large B-cell lymphoma are enzymatically inert.

  2. D2HGDH mutation is not associated with glioblastoma.

  3. We did not find evidence for mutations in the genes D2HGDH and L2HGDH (show L2HGDH ELISA Kits) as an alternative mechanism for raised 2-hydroxyglutarate levels in brain tumours

  4. Two novel pathogenic mutations in D-2-hydroxyglutarate dehydrogenase gene in patient with a mild presentation and asymptomatic siblings with D-2-hydroxyglutaric aciduria with a splice error (IVS4-2A-->G) and a missense mutation (c.1315A-->G;p.Asn439Asp).

  5. This enzyme assay will have utility in differentiating patients with 2-hydroxyglutaric aciduria and in assessing the residual activities linked to pathogenic mutations in the D2HGDH gene

D2HGDH Antigen Profile

Antigen Summary

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.

Gene names and symbols associated with D2HGDH

  • D-2-hydroxyglutarate dehydrogenase (D2hgdh) antibody
  • D-2-hydroxyglutarate dehydrogenase (D2HGDH) antibody
  • D-2-hydroxyglutarate dehydrogenase (d2hgdh) antibody
  • AA408776 antibody
  • AA408778 antibody
  • AI325464 antibody
  • D2HGD antibody
  • RGD1307976 antibody
  • zgc:158661 antibody

Protein level used designations for D2HGDH

D-2-hydroxyglutarate dehydrogenase, mitochondrial

98314 Mus musculus
301624 Rattus norvegicus
728294 Homo sapiens
533003 Bos taurus
565889 Danio rerio
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