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D-Amino Acid Oxidase Activator Proteins (DAOA)

DAOA encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Additionally we are shipping D-Amino Acid Oxidase Activator Antibodies (20) and D-Amino Acid Oxidase Activator Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DAOA 267012 P59103
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Top D-Amino Acid Oxidase Activator Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 9 to 11 Days
$229.85
Details

DAOA Proteins by Origin and Source

Origin Expressed in Conjugate
Human
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More Proteins for D-Amino Acid Oxidase Activator (DAOA) Interaction Partners

Human D-Amino Acid Oxidase Activator (DAOA) interaction partners

  1. DAOA gene may contribute to the risk for Psychotic disorders and that this gene may play a role as a modulator of executive function.

  2. pLG72 level being significantly increased in the serum of patients with schizophrenia, have led us to propose that the ROS (show ROS1 Proteins) enhancement in mental diseases may be from the overexpression of pLG72 in brain cells.

  3. Report in silico analysis of DAOA for the design of inhibitors for treatment of schizophrenia.

  4. This study suggested that structural lipid alterations in oligodendrocyte glycosynapses are responsible for dysconnectivity in schizophrenia and that increased expression of G72 protein may play a role in the development of abnormal glycosynapses.

  5. DAOA (or G72) gene encodes for a protein that binds to and activates the D-serine amino acid oxidase that acts as a coactivator of the glycine binding site on the glutamatergic N-methyl D-aspartate (NMDA) receptor.

  6. the mitochondrial methionine-R-sulfoxide reductase B2 (MSRB2 (show MSRB2 Proteins)) is a specific interaction partner of LG72.

  7. DAOA genetic polymorphism were not found to confer a statistically significant increased risk of Schizophrenia, bipolar disorder or depressive disorder.

  8. Suggest chronic nicotine administration improves cognitive symptoms in G72 mouse model of schizophrenia.

  9. study reports G72/G30 expression profiles and behavioral changes in a G72/G30 transgenic mouse model; the transcriptome profile changes and multiple mouse behavioral effects suggest that the G72 gene may play a role in modulating behaviors relevant to psychiatric disorders

  10. Results demonstrate that expression of the human G72/G30 gene locus in mice produces behavioral phenotypes that are relevant to schizophrenia and implicate LG72-induced mitochondrial and synaptic defects as a possible pathomechanism of this disease.

Xenopus laevis D-Amino Acid Oxidase Activator (DAOA) interaction partners

  1. tadpoles contained high concentrations of D-proline close to the final developmental stage and nearly no D-amino acids were detected in the adult frog, indicating that D-amino acid oxidase (show DAO Proteins) functions in metamorphosis.

D-Amino Acid Oxidase Activator (DAOA) Protein Profile

Protein Summary

This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with DAOA

  • D-amino acid oxidase activator (DAOA)
  • D-amino-acid oxidase (DAO)
  • D-amino-acid oxidase (dao)
  • D-amino-acid oxidase (SJAG_02496)
  • D-amino acid oxidase (Dao)
  • D-amino-acid oxidase (oxda)
  • daao protein
  • damox protein
  • DAO protein
  • DKFZp469N2232 protein
  • LG72 protein
  • MGC114783 protein
  • oxda protein
  • SG72 protein

Protein level used designations for DAOA

G72 transcript , schizophrenia- and bipolar disorder-associated protein G72 , D-amino-acid oxidase , D-amino acid oxidase , D-amino-acid oxidase-like

GENE ID SPECIES
267012 Homo sapiens
416894 Gallus gallus
706373 Macaca mulatta
735104 Xenopus laevis
743881 Pan troglodytes
7049247 Schizosaccharomyces japonicus yFS275
9794199 Arthrobacter arilaitensis Re117
100036595 Xenopus (Silurana) tropicalis
100171568 Pongo abelii
100192327 Cavia porcellus
100306742 Salmo salar
100414426 Callithrix jacchus
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