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D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. Additionally we are shipping D-Dopachrome Tautomerase Antibodies (63) and D-Dopachrome Tautomerase Proteins (18) and many more products for this protein.
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High MIF-2 (show CENPC1 ELISA Kits) levels are predictive of the development of organ dysfunction in myocardial ischemia reperfusion injury.
Both p53 (show TP53 ELISA Kits) wildtype and mutant human lung adenocarcinoma tumors rely on MIF (show AMH ELISA Kits) family members for maximal cell growth and survival.
findings identify DDT as a functionally redundant but more potent cytokine to MIF (show AMH ELISA Kits) in cancer and suggest that current attempts to inhibit MIF (show AMH ELISA Kits) signaling may fail because of DDT compensation.
D-dopachrome tautomerase secreted from adipocytes acts on preadipocytes to promote IL-6 (show IL6 ELISA Kits) expression and to inhibit adipogenesis by suppressing the induction of genes encoding adipogenic regulators
DDT acts on adipocytes to regulate lipid metabolism through AMPK (show PRKAA1 ELISA Kits) and/or PKA pathway(s) and improves glucose intolerance caused by obesity.
These data indicate that D-DT is a MIF (show AMH ELISA Kits)-like cytokine.
D-DT-dependent beta-catenin (show CTNNB1 ELISA Kits) stabilization is regulated by COX-2 (show COX2 ELISA Kits) expression, suggesting the existence of an amplification loop between COX-2 (show COX2 ELISA Kits)- and beta-catenin (show CTNNB1 ELISA Kits)-mediated transcription in these cells
role of tautomerase active site of macrophage migration inhibitory factor (show MIF ELISA Kits) as a potential target for discovery of novel anti-inflammatory agents
DDT is for the first time demonstrated in the skin and can be related to inflammation, and its covariation with MIF (show AMH ELISA Kits) strengthens this observation.
D-dopachrome tautomerase (D-DT) and macrophage migration inhibitory factor (show MIF ELISA Kits), individually and additively, promote vascular endothelial growth factor and CXCL8 (show IL8 ELISA Kits) expression in human lung adenocarcinoma cell lines.
cardiomyocyte secretion of DDT has important autocrine/paracrine effects during ischemia-reperfusion that protect the heart against injury
These data point to a potential involvement of D-dopachrome tautomerase activity in the mature mouse brain, and suggest some functional and evolutionary relationship between innate immunity and tautomerization of D-dopachrome in mammalian species
These data indicate that D-DT is a MIF (show MIF ELISA Kits)-like cytokine.
D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22.
, D-dopachrome decarboxylase-A
, D-dopachrome tautomerase-A
, D-dopachrome decarboxylase-B
, D-dopachrome tautomerase-B
, D-dopachrome tautomerase
, dopachrome isomerase
, phenylpyruvate tautomerase II