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anti-DAN Domain Family, Member 5 (DAND5) Antibodies

DAND5 encodes a member of the BMP (bone morphogenic protein) antagonist family. Additionally we are shipping DAND5 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DAND5 199699 Q8N907
DAND5 23863 Q76LW6
DAND5    
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Top anti-DAND5 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-DAND5 AntibodyTitration: 1.0 µg/mL  Positive Control: MCF7 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-DAND5 AntibodyTitration: 1.0 µg/mL  Positive Control: Hela Whole cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Mouse Un-conjugated FACS, IF HEK293T cells transfected with either RC221703 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DAND5 antibody (ABIN2455143), and then analyzed by flow cytometry. Anti-DAND5 mouse monoclonal antibody (ABIN2455143) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAND5 (RC221703). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC221703 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DAND5 antibody (ABIN2455031), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DAND5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DAND5. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated FACS, IF 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

DAND5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
,
,
, , , , , , , , , , ,
Mouse (Murine)


Rat (Rattus)


More Antibodies against DAND5 Interaction Partners

Human DAN Domain Family, Member 5 (DAND5) interaction partners

  1. A gain-of-function cDNA screen reveals that Coco, a secreted antagonist of TGF-beta (show TGFB1 Antibodies) ligands, induces dormant breast cancer cells to undergo reactivation in the lung.

Xenopus laevis DAN Domain Family, Member 5 (DAND5) interaction partners

  1. Coco binds to TGFbeta1 (show TGFB1 Antibodies) and enhances TGFbeta1 (show TGFB1 Antibodies) binding to its receptor Alk5 (show TGFBR1 Antibodies) thus acting as both an inhibitor and an enhancer of signaling, depending on the ligand it binds.

  2. Coco required to prevent Activin (show Actbeta Antibodies) and Nodal signals in dorsal marginal side of embryo from invading the prospective ectoderm, thereby restricting endoderm- and mesoderm-inducing signals to the vegetal and marginal zones of the pre-gastrula Xenopus embryo

  3. Data suggest that Coco acts as a critical target of flow, suggesting that symmetry is broken by flow-mediated left-asymmetric release of Nodal repression at the midline.

  4. Coco directly inhibits derriere (show GDF3 Antibodies) and Xnr1 (show NODAL Antibodies), and with them define a posttranscriptionally regulated signaling center which is a necessary link in the signaling chain leading to an increased TGF-beta (show TGFB1 Antibodies) signal on the left side of the embryo.

Mouse (Murine) DAN Domain Family, Member 5 (DAND5) interaction partners

  1. Cerl2 plays an important role during heart development.

  2. The consequent prolonged Nodal activity in the node by the absence of Cerl2 affects local Nodal expression and prolongs its expression in the lateral plate mesoderm.

  3. Decay of Cerl2 mRNA on the left is initiated by the leftward flow and further enhanced by the operation of Wnt (show WNT2 Antibodies)-Cerl2 interlinked feedback loops.

  4. Study shows the cilia protein Arl13b (show ARL13B Antibodies) is required for left right axis specification as its absence results in heterotaxia; the defect originates in the node where Cerl2 is not downregulated and asymmetric expression of Nodal is not maintained resulting in symmetric expression of both genes.

  5. Cerl-2 plays a key role in restricting the Nodal signaling pathway toward the left side of the mouse embryo by preventing its activity in the right side

  6. cCer and mouse Cerl-2 have evolved distinct regulatory mechanisms but retained a conserved function in left-right development, which is to restrict Nodal activity to the left side of the embryo.

DAND5 Antigen Profile

Protein Summary

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Gene names and symbols associated with DAND5

  • DAN domain family member 5, BMP antagonist (DAND5) antibody
  • DAN domain family member 5, BMP antagonist (dand5) antibody
  • DAN domain family, member 5 (Dand5) antibody
  • 51-B6 antibody
  • cer2 antibody
  • Cerl-2 antibody
  • cerl2 antibody
  • Cerr2 antibody
  • cktsf1b3 antibody
  • coco antibody
  • crl2 antibody
  • dante antibody
  • Dte antibody
  • grem3 antibody
  • SP1 antibody
  • xCoco antibody

Protein level used designations for DAND5

DAN domain family member 5 , DAN domain family, member 5 , cerberus 2 , cerberus-like 2 , cerberus-like protein 2 , cerl-2 , cysteine knot superfamily 1, BMP antagonist 3 , gremlin-3 , cerberus-like 2 protein , dante

GENE ID SPECIES
199699 Homo sapiens
594864 Xenopus laevis
23863 Mus musculus
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