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anti-DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) (DCUN1D1) Antibodies

Part of an E3 ubiquitin ligase complex for neddylation. Additionally we are shipping DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCUN1D1 54165 Q96GG9
DCUN1D1 114893 Q9QZ73
DCUN1D1 310324  
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Top anti-DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-DCUN1D1 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-DCUN1D1  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate  DCUN1D1 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-DCUN1D1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: PANC1 cell lysate WB Suggested Anti-DCUN1D1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: PANC1 cell lysate  DCUN1D1 is supported by BioGPS gene expression data to be expressed in PANC1 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, IHC (p), WB Staining of paraffin embedded Human Kidney using DCUN1D1 antibody at 5 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Staining of HepG2 lysate using DCUN1D1 antibody at 0.5 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to DCUN1D1 on HeLa cell (antibody concentration 10 µg/mL). DCUN1D1 monoclonal antibody (M01), clone 3D7 Western Blot analysis of DCUN1D1 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB DCUN1D1 monoclonal antibody (M02), clone 4B5. Western Blot analysis of DCUN1D1 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

DCUN1D1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) Antibodies

  1. Chicken Polyclonal DCUN1D1 Primary Antibody for IHC, WB - ABIN2775480 : Kurz, Ozlü, Rudolf, ORourke, Luke, Hofmann, Hyman, Bowerman, Peter: The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. in Nature 2005 (PubMed)

More Antibodies against DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) Interaction Partners

Human DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) (DCUN1D1) interaction partners

  1. The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.

  2. SCCRO3 functions as a tumor suppressor by antagonizing the neddylation activity of SCCRO

  3. Distinct preferences of UBC12 (show ube2m Antibodies) and UBE2F (show UBE2F Antibodies) peptides for inhibiting different DCNLs, including the oncogenic DCNL1.

  4. substrate engagement prompts DCNL1 recruitment that facilitates the initiation of CUL2 (show CUL2 Antibodies) neddylation and define DCNL1 as a "substrate sensor switch" for ECV activation.

  5. a mono-ubiquitination-mediated mechanism that governs nuclear-cytoplasmic trafficking of hDCNL1, thereby regulating hDCNL1-dependent activation of the cullin-RING E3 ubiquitin ligases in selected cellular compartments.

  6. Loss of SCRO expression in primary adrenocortical carcinoma is associated with worse outcome and may be a marker of progressive dedifferentiation in these tumors.

  7. SCCRO regulates Gli1 (show GLI1 Antibodies)--a key regulator of the hedgehog (show SHH Antibodies) (HH) pathway.

  8. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

  9. SCCRO-induced invasion involves activation of MMP2 (show MMP2 Antibodies) transcription in an AP2 (show GTF3A Antibodies)- and p53 (show TP53 Antibodies)-dependent manner.

  10. The GG genotype of the DCUN1D1 rs4859147 Single Nucleotide Polymorphism represents a risk factor for the development of frontotemporal lobar degeneration , increasing the risk of about fourfold.

Mouse (Murine) DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) (DCUN1D1) interaction partners

  1. SCCRO family members cooperatively regulate neddylation and cell proliferation.

  2. The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.

  3. in the nucleus, SCCRO enhances recruitment of Ubc12 (show ube2m Antibodies) to Cul1 (show CUL1 Antibodies) to promote neddylation

  4. SCCRO promotes glioma formation and malignant progression.

  5. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

DCN1, Defective in Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae) (DCUN1D1) Antigen Profile

Protein Summary

Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity).

Gene names and symbols associated with DCUN1D1

  • DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) (dcun1d1) antibody
  • DCN1-like protein 1 (dcnl1) antibody
  • DCN1, defective in cullin neddylation 1, domain containing 1 (dcun1d1) antibody
  • DCN1, defective in cullin neddylation 1, domain containing 1 (DCUN1D1) antibody
  • DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) (DCUN1D1) antibody
  • DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) (Dcun1d1) antibody
  • DCNL1 antibody
  • DCUN1L1 antibody
  • fd19a01 antibody
  • pTes3 antibody
  • Rp42 antibody
  • SCCRO antibody
  • SCRO antibody
  • Tes3 antibody
  • wu:fd19a01 antibody
  • zgc:66414 antibody

Protein level used designations for DCUN1D1

DCN1-like protein 1 , DCUN1 domain-containing protein 1 , RP42 homolog , defective in cullin neddylation protein 1-like protein 1 , squamous cell carcinoma related oncogene , squamous cell carcinoma-related oncogene , testis derived transcript 3 , testis-specific protein 3

GENE ID SPECIES
327232 Danio rerio
100301762 Oncorhynchus mykiss
414532 Xenopus laevis
54165 Homo sapiens
424963 Gallus gallus
606979 Canis lupus familiaris
539869 Bos taurus
114893 Mus musculus
310324 Rattus norvegicus
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