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DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) Proteins (DCP1A)

Decapping is a key step in general and regulated mRNA decay. Additionally we are shipping DCP1A Antibodies (80) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DCP1A 75901 Q91YD3
Rat DCP1A DCP1A 361109  
DCP1A 55802 Q9NPI6
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Top DCP1A Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DCP1A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) Interaction Partners

Mouse (Murine) DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) interaction partners

  1. PKR (show EIF2AK2 Proteins)-induced translational inhibition appears to be specific to Dcp1a because the expression of other P-body components, Pan2 (show PAN2 Proteins), Pan3 (show PCSK1N Proteins), Ccr4 (show CCR4 Proteins), or Caf1 (show CNOT7 Proteins), did not result in the inhibition of poliovirus gene expression or induce eIF2alpha (show EIF2A Proteins) phosphorylation.

  2. ERK (show EPHB2 Proteins)-phosphorylated Dcp1a enhances its interaction with the decapping enzyme Dcp2 (show DCP2 Proteins) during early differentiation of 3T3-L1 cells.

  3. Recruitment of DCP1A and DCP2 (show DCP2 Proteins) increases the mRNA degradation capacity of the maturing oocyte so that by the 2-cell stage, most of the maternal mRNA is degraded.

  4. The results showed that DCP1A and DCP2 (show DCP2 Proteins) are critical in the transition from mRNA stability to instability during meiotic maturation and that mRNA degradation must be successful to execute the oocyte-to-zygote transition.

  5. Data show the presence of P-body-like foci in mouse oocytes, as revealed by the presence of Dcp1a and the colocalization of RNA-associated protein 55 (RAP55 (show LSM14A Proteins)) and the DEAD box RNA helicase (show DDX56 Proteins) Rck/p54 (show DDX6 Proteins).

  6. Overexpression of wild-type SMIF enhanced expression of TGFbeta/BMP (show TGFb Proteins) regulated genes, whereas a dominant-negative SMIF mutant suppressed expression.

  7. These findings suggest a novel post-translational modification that may influence the function of Dcp1a in response to various physiological cues.

Zebrafish DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) interaction partners

  1. Overexpression of wild-type SMIF enhanced expression of TGFbeta/BMP (show TGFb Proteins) regulated genes, whereas a dominant-negative SMIF mutant suppressed expression.

Human DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) interaction partners

  1. The assembly of EDC4 (show EDC4 Proteins) and Dcp1a into processing bodies is critical for the translational regulation of IL-6 (show IL6 Proteins).

  2. Phosphorylation at serine 315, serine 319, and threonine 321 of DCP1A modulates IL-8 (show IL8 Proteins) expression during respiratory syncytial virus infection.

  3. The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells.

  4. Malin (show NHLRC1 Proteins) regulates the recruitment of mRNA-decapping enzyme 1A (Dcp1a) to processing bodies.

  5. PNRC2 (show PNRC2 Proteins) acts in synergy with Dcp1a to stimulate the decapping activity of Dcp2 (show DCP2 Proteins) by bridging the interaction between Dcp1a and Dcp2 (show DCP2 Proteins).

  6. Reveal DCP1a as a multifunctional regulator of mRNA expression and suggest a role for JNK (show MAPK8 Proteins) kinase phosphorylation in controlling the subcellular localization of DCP1a in response to stress or inflammatory stimuli.

  7. Data show the presence of P-body-like foci in mouse oocytes, as revealed by the presence of Dcp1a and the colocalization of RNA-associated protein 55 (RAP55 (show LSM14A Proteins)) and the DEAD box RNA helicase (show DDX5 Proteins) Rck/p54 (show DDX6 Proteins).

  8. Overexpression of wild-type SMIF enhanced expression of TGFbeta/BMP (show TGFb Proteins) regulated genes, whereas a dominant-negative SMIF mutant suppressed expression.

DCP1A Protein Profile

Protein Summary

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.

Gene names and symbols associated with DCP1A

  • DCP1 decapping enzyme homolog A (S. cerevisiae) (DCP1A)
  • DCP1 decapping enzyme homolog A (DCP1A)
  • DCP1 decapping enzyme homolog A (S. cerevisiae) (Dcp1a)
  • DCP1 decapping enzyme homolog A (S. cerevisiae) (dcp1a)
  • decapping mRNA 1A (DCP1A)
  • decapping mRNA 1A (dcp1a)
  • 1110066A22Rik protein
  • 4930568L04Rik protein
  • AU019772 protein
  • D14Ertd817e protein
  • DCP1A protein
  • HSA275986 protein
  • mitc1 protein
  • Nbla00360 protein
  • RGD1561298 protein
  • smad4ip1 protein
  • smif protein

Protein level used designations for DCP1A

DCP1 decapping enzyme homolog A (S. cerevisiae) , DCP1 decapping enzyme homolog A , mRNA-decapping enzyme 1A , MAD homolog 4 interacting transcription coactivator 1 , MAD homolog 4-interacting transcription coactivator 1 , Smad4-interacting transcriptional co-activator , decapping enzyme , transcription factor SMIF , test2 , decapping enzyme hDcp1a , putative protein product of Nbla00360

GENE ID SPECIES
460444 Pan troglodytes
694198 Macaca mulatta
100051259 Equus caballus
100481669 Ailuropoda melanoleuca
100591367 Nomascus leucogenys
607346 Canis lupus familiaris
783258 Bos taurus
75901 Mus musculus
361109 Rattus norvegicus
360153 Danio rerio
415992 Gallus gallus
100623102 Sus scrofa
55802 Homo sapiens
443654 Xenopus laevis
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