Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Decapping is a key step in general and regulated mRNA decay. Additionally we are shipping DCP1A Antibodies (86) and DCP1A Proteins (5) and many more products for this protein.
PKR (show EIF2AK2 ELISA Kits)-induced translational inhibition appears to be specific to Dcp1a because the expression of other P-body components, Pan2 (show PAN2 ELISA Kits), Pan3 (show PCSK1N ELISA Kits), Ccr4 (show CCR4 ELISA Kits), or Caf1 (show CNOT7 ELISA Kits), did not result in the inhibition of poliovirus gene expression or induce eIF2alpha (show EIF2A ELISA Kits) phosphorylation.
ERK (show EPHB2 ELISA Kits)-phosphorylated Dcp1a enhances its interaction with the decapping enzyme Dcp2 (show DCP2 ELISA Kits) during early differentiation of 3T3-L1 cells.
Recruitment of DCP1A and DCP2 (show DCP2 ELISA Kits) increases the mRNA degradation capacity of the maturing oocyte so that by the 2-cell stage, most of the maternal mRNA is degraded.
The results showed that DCP1A and DCP2 (show DCP2 ELISA Kits) are critical in the transition from mRNA stability to instability during meiotic maturation and that mRNA degradation must be successful to execute the oocyte-to-zygote transition.
Data show the presence of P-body-like foci in mouse oocytes, as revealed by the presence of Dcp1a and the colocalization of RNA-associated protein 55 (RAP55 (show LSM14A ELISA Kits)) and the DEAD box RNA helicase (show DDX56 ELISA Kits) Rck/p54 (show DDX6 ELISA Kits).
Overexpression of wild-type SMIF enhanced expression of TGFbeta/BMP (show TGFb ELISA Kits) regulated genes, whereas a dominant-negative SMIF mutant suppressed expression.
These findings suggest a novel post-translational modification that may influence the function of Dcp1a in response to various physiological cues.
The results suggest that overexpressed Dcp1a and GW182 can form different cytoplasmic aggregates and play distinct biological roles in the miRNA pathway.
The E3 ligase TRAF6 (show TRAF6 ELISA Kits) binds to DCP1a and indirectly regulates DCP1a phosphorylation, expression of decapping factors, and gene-specific mRNA decay.
DCP1A rs11551405 may have a prognostic effect on survival of CM patients.
The assembly of EDC4 (show EDC4 ELISA Kits) and Dcp1a into processing bodies is critical for the translational regulation of IL-6 (show IL6 ELISA Kits).
Phosphorylation at serine 315, serine 319, and threonine 321 of DCP1A modulates IL-8 (show IL8 ELISA Kits) expression during respiratory syncytial virus infection.
The data indicates that DCP2 (show DCP2 ELISA Kits) activation by DCP1 (show ACE ELISA Kits) occurs preferentially on the EDC4 (show EDC4 ELISA Kits) scaffold, which may serve to couple DCP2 (show DCP2 ELISA Kits) activation by DCP1 (show ACE ELISA Kits) with 5'-to-3' mRNA degradation by XRN1 (show XRN1 ELISA Kits) in human cells.
Malin (show NHLRC1 ELISA Kits) regulates the recruitment of mRNA-decapping enzyme 1A (Dcp1a) to processing bodies.
PNRC2 (show PNRC2 ELISA Kits) acts in synergy with Dcp1a to stimulate the decapping activity of Dcp2 (show DCP2 ELISA Kits) by bridging the interaction between Dcp1a and Dcp2 (show DCP2 ELISA Kits).
Reveal DCP1a as a multifunctional regulator of mRNA expression and suggest a role for JNK (show MAPK8 ELISA Kits) kinase phosphorylation in controlling the subcellular localization of DCP1a in response to stress or inflammatory stimuli.
Data show the presence of P-body-like foci in mouse oocytes, as revealed by the presence of Dcp1a and the colocalization of RNA-associated protein 55 (RAP55 (show LSM14A ELISA Kits)) and the DEAD box RNA helicase (show DDX5 ELISA Kits) Rck/p54 (show DDX6 ELISA Kits).
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.
DCP1 decapping enzyme homolog A (S. cerevisiae)
, DCP1 decapping enzyme homolog A
, mRNA-decapping enzyme 1A
, MAD homolog 4 interacting transcription coactivator 1
, MAD homolog 4-interacting transcription coactivator 1
, Smad4-interacting transcriptional co-activator
, decapping enzyme
, transcription factor SMIF
, decapping enzyme hDcp1a
, putative protein product of Nbla00360