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DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) ELISA Kits

The protein encoded by DCP2 is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). Additionally we are shipping DCP2 Antibodies (58) and DCP2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse DCP2 DCP2 70640 Q9CYC6
Anti-Human DCP2 DCP2 167227 Q8IU60
Anti-Rat DCP2 DCP2 291604  
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More ELISA Kits for DCP2 Interaction Partners

Mouse (Murine) DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) interaction partners

  1. ERK (show EPHB2 ELISA Kits)-phosphorylated Dcp1a (show DCP1A ELISA Kits) enhances its interaction with the decapping enzyme (show DCP1A ELISA Kits) Dcp2 during early differentiation of 3T3-L1 cells.

  2. Recruitment of DCP1A (show DCP1A ELISA Kits) and DCP2 increases the mRNA degradation capacity of the maturing oocyte so that by the 2-cell stage, most of the maternal mRNA is degraded.

  3. The results showed that DCP1A (show DCP1A ELISA Kits) and DCP2 are critical in the transition from mRNA stability to instability during meiotic maturation and that mRNA degradation must be successful to execute the oocyte-to-zygote transition.

  4. In this study the increase in Irf-7 (show IRF7 ELISA Kits) mRNA within the background of reduced Dcp2 levels was attributed to a stabilization of the Irf-7 (show IRF7 ELISA Kits) mRNA, suggesting that Dcp2 normally modulates Irf-7 (show IRF7 ELISA Kits) mRNA stability.

  5. Like Dcp2, Nudt16 (show NUDT16 ELISA Kits) also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

Human DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) interaction partners

  1. Human Dcp2 levels and activity are controlled by a competition between decapping complex assembly and Dcp2 degradation.

  2. The data indicates that DCP2 activation by DCP1 (show ACE ELISA Kits) occurs preferentially on the EDC4 (show EDC4 ELISA Kits) scaffold, which may serve to couple DCP2 activation by DCP1 (show ACE ELISA Kits) with 5'-to-3' mRNA degradation by XRN1 (show XRN1 ELISA Kits) in human cells.

  3. Data show that Y14 (show RBM8A ELISA Kits) interacts directly with the decapping factor Dcp2 and the 5' cap structure of mRNAs via different but overlapping domains.

  4. PNRC2 (show PNRC2 ELISA Kits) acts in synergy with Dcp1a (show DCP1A ELISA Kits) to stimulate the decapping activity of Dcp2 by bridging the interaction between Dcp1a (show DCP1A ELISA Kits) and Dcp2.

  5. Like Dcp2, Nudt16 (show NUDT16 ELISA Kits) also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

  6. an mRNA decapping enzyme (show DCPS ELISA Kits) demonstrated to contain intrinsic decapping activity

  7. Human Dcp2 is a catalytically active mRNA decapping enzyme (show DCPS ELISA Kits) that localizes to the cytoplasm

  8. LSm1 (show LSM1 ELISA Kits)-7 proteins colocalize with DCP1 (show ACE ELISA Kits),DCP2 and Xrn1 (show XRN1 ELISA Kits) in cytoplasmic foci

  9. These data support the novel notion of the association between Ro52 (show TRIM21 ELISA Kits) with hDCP2 protein in cytoplasmic p-bodies, playing a role in mRNA metabolism in response to cellular stimulation.

DCP2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with DCP2

  • mRNA-decapping enzyme 2 (CpipJ_CPIJ019463) antibody
  • mRNA-decapping enzyme 2 (PTRG_05936) antibody
  • mRNA-decapping enzyme 2 (dcp2) antibody
  • mRNA-decapping enzyme 2 (MCYG_05106) antibody
  • mRNA-decapping enzyme 2 (MGYG_07617) antibody
  • mRNA-decapping enzyme 2 (PGTG_03310) antibody
  • mRNA-decapping enzyme 2 (Tsp_04018) antibody
  • DCP2 decapping enzyme homolog (S. cerevisiae) (dcp2) antibody
  • DCP2 decapping enzyme homolog (S. cerevisiae) (DCP2) antibody
  • DCP2 decapping enzyme homolog (S. cerevisiae) (Dcp2) antibody
  • decapping mRNA 2 (DCP2) antibody
  • decapping mRNA 2 (Dcp2) antibody
  • 2410015D23Rik antibody
  • 5730537H01Rik antibody
  • AL118268 antibody
  • DDBDRAFT_0185453 antibody
  • DDBDRAFT_0252811 antibody
  • DDB_0185453 antibody
  • DDB_0252811 antibody
  • NUDT20 antibody
  • RGD1562909 antibody

Protein level used designations for DCP2

mRNA-decapping enzyme 2 , DCP2 decapping enzyme homolog , m7GpppN-mRNA hydrolase , hDpc , nudix (nucleoside diphosphate linked moiety X)-type motif 20

GENE ID SPECIES
6054129 Culex quinquefasciatus
6344191 Pyrenophora tritici-repentis Pt-1C-BFP
8624030 Dictyostelium discoideum AX4
9230993 Arthroderma otae CBS 113480
10025613 Arthroderma gypseum CBS 118893
10538062 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10904275 Trichinella spiralis
100195938 Salmo salar
489086 Canis lupus familiaris
70640 Mus musculus
100127054 Pongo abelii
167227 Homo sapiens
291604 Rattus norvegicus
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