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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked Proteins (DDX3X)

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DDX3X Antibodies (201) and DDX3X Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDX3X 1654 O00571
Rat DDX3X DDX3X 317335  
DDX3X 13205 Q62167
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Top DDX3X Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

DDX3X Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) Interaction Partners

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) interaction partners

  1. Data show that knockdown of RNA helicase DDX3 in breast cancer MCF-7 and MDA-MB-231 cells resulted in decreased proliferation rates.

  2. Data show that high cytoplasmic DEAD-box helicase 3 (DDX3) expression correlated with nuclear beta-catenin (show CTNNB1 Proteins) expression, a marker of activated Wnt (show WNT2 Proteins) signaling.

  3. Our results suggest that the intrinsically disordered N-terminal domain of DDX3 regulates its functions in translation by acting prior to the recruitment of the 43S pre-initiation complex onto the viral 5'-UTR.

  4. The results do not support our hypothesis that common germline genetic variants in the DDX3X genes is associated with the risk of developing medulloblastoma.

  5. analysis of the structural and functional core of the DDX3 subfamily of DEAD-box proteins

  6. The DDX3 may participate in antiviral innate immunity, at least in part, by translational control of interferon-induced protein kinase (PACT).

  7. As such, DDX3 has been shown to play roles both upstream and downstream of I-kappa beta kinase epsilon (IKKepsilon (show IKBKE Proteins))/TANK-binding kinase 1 (show TBK1 Proteins), leading to IFN-beta (show IFNB1 Proteins) production.

  8. Data show that DEAD-box helicase 3 (DDX3) had a significant prognostic predictive power in colorectal cancer at both RNA and protein level.

  9. Taken together, our result demonstrates that Ketorolac salt is a newly discovered bioactive compound against DDX3 and this compound can be used as an ideal drug candidate to treat DDX3 associated oral cancer.

  10. Loss of DDX3 function either by shRNA or by RK-33 impaired Wnt (show WNT2 Proteins) signaling through disruption of the DDX3-beta-catenin (show CTNNB1 Proteins) axis and inhibited non-homologous end joining-the major DNA repair pathway in mammalian somatic cells.

DDX3X Protein Profile

Protein Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with DDX3X

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DBX)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (ddx3x)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (DDX3X)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (Ddx3x)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (ddx3x)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 (Ddx3)
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked (Ddx3x)
  • An3 protein
  • D1Pas1-rs2 protein
  • DBX protein
  • Ddx3 protein
  • DDX3X protein
  • Ddx3y protein
  • DDX14 protein
  • Fin14 protein
  • HLP2 protein
  • pl10 protein

Protein level used designations for DDX3X

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 , ATP-dependent RNA helicase DDX3X-like , ATP-dependent RNA helicase DDX3X , CAP-Rf , DEAD box protein 3, X-chromosomal , DEAD box, X isoform , DEAD/H box-3 , helicase like protein 2 , helicase-like protein 2 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked , ATP-dependent RNA helicase DDX3Y , DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y-linked , D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3 , D1Pas1-related sequence 2 , DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3 , DEAD box RNA helicase DEAD3 , DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2) , embryonic RNA helicase , fibroblast growth factor inducible 14 , mDEAD3

GENE ID SPECIES
448820 Sus scrofa
702315 Macaca mulatta
706891 Macaca mulatta
100028065 Monodelphis domestica
100082235 Ornithorhynchus anatinus
100348597 Oryctolagus cuniculus
100399667 Callithrix jacchus
100446823 Pongo abelii
100464548 Ailuropoda melanoleuca
100544480 Meleagris gallopavo
100555462 Anolis carolinensis
1654 Homo sapiens
317335 Rattus norvegicus
379975 Xenopus laevis
100312982 Rattus norvegicus
480886 Canis lupus familiaris
418567 Gallus gallus
510093 Bos taurus
13205 Mus musculus
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