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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 Proteins (DDX41)

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DDX41 Antibodies (67) and DDX41 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDX41 51428 Q9UJV9
DDX41 72935 Q91VN6
Rat DDX41 DDX41 314336  
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Top DDX41 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DDX41 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) Interaction Partners

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) interaction partners

  1. This study expands both the mutation and phenotypic spectra observed in families with germ line DDX41 mutations.

  2. corresponding deletions on 5q35.3 present in 6% of cases led to haploinsufficient DDX41 expression. DDX41 lesions caused altered pre-mRNA splicing and RNA processing

  3. results suggest a mechanism whereby c-di-GMP (show NT5C2 Proteins) and c-di-AMP (show APRT Proteins) are detected by DDX41, which forms a complex with STING to signal to TBK1 (show TBK1 Proteins)-IRF3 (show IRF3 Proteins) and activate the interferon (show IFNA Proteins) response

  4. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

  5. The N-terminal domain of Abs interacts with the phox homology (PX) domain of SNX2 (show SNX2 Proteins) suggesting that PX domains may also participate in protein-protein interaction.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) interaction partners

  1. Tyr364 and Tyr414 of DDX41 are critical for its recognition of AT-rich DNA and binding to STING, and tandem mass spectrometry identifies Tyr414 as the BTK (show BTK Proteins) phosphorylation site.

  2. TRIM21 (show TRIM21 Proteins) is an interferon (show IFNA Proteins)-inducible E3 ligase that induces the Lys48-linked ubiquitination and degradation of DDX41 and negatively regulates the innate immune response to intracellular double-stranded DNA.

  3. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

DDX41 Protein Profile

Protein Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.

Gene names and symbols associated with DDX41

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (DDX41)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (ddx41)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (Ddx41)
  • 2900024F02Rik protein
  • AA958953 protein
  • ABS protein
  • AI324246 protein
  • DDX41 protein
  • wu:fb92e02 protein
  • zgc:55896 protein

Protein level used designations for DDX41

DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 , DEAD-box protein abstrakt , probable ATP-dependent RNA helicase DDX41-like , 2900024F02Rik , DEAD box protein 41 , DEAD box protein abstrakt homolog , probable ATP-dependent RNA helicase DDX41 , putative RNA helicase

GENE ID SPECIES
427630 Gallus gallus
462310 Pan troglodytes
700742 Macaca mulatta
100031917 Monodelphis domestica
100058316 Equus caballus
100215941 Hydra magnipapillata
100401323 Callithrix jacchus
100437507 Pongo abelii
100474236 Ailuropoda melanoleuca
100491281 Xenopus (Silurana) tropicalis
100550300 Meleagris gallopavo
100554935 Anolis carolinensis
100638079 Amphimedon queenslandica
51428 Homo sapiens
479274 Canis lupus familiaris
505276 Bos taurus
72935 Mus musculus
314336 Rattus norvegicus
394020 Danio rerio
101102307 Ovis aries
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