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This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family. Additionally we are shipping DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 53 Antibodies (43) and many more products for this protein.
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Human DDX53 Protein expressed in Wheat germ - ABIN1351369
Kim, Park, Kim, Choi, Lee, Lee, Choe, Kim, Jeoung: miR-200b and cancer/testis antigen CAGE form a feedback loop to regulate the invasion and tumorigenic and angiogenic responses of a cancer cell line to microtubule-targeting drugs. in The Journal of biological chemistry 2013
Results provide evidence that miR (show MLXIP Proteins)-30a forms a positive feedback loop with CAGE to regulate the expression of p53 (show TP53 Proteins) confering resistance to anti-cancer drugs.
miR (show MLXIP Proteins)-217-CAGE feedback loop serves as a target for overcoming resistance to various anti-cancer drugs, including EGFR (show EGFR Proteins) and HER2 (show ERBB2 Proteins) inhibitors.
Results show the direct regulation of CAGE expression by HDAC3 (show HDAC3 Proteins) and that HDAC3 (show HDAC3 Proteins)-CAGE axis regulates the activation of EGFR (show EGFR Proteins). HDAC3 (show HDAC3 Proteins) targets CAGE to regulate the tumorigenic potential and angiogenic potential of cancer cells.
CAGE induced the interaction between histone deacetylase 2 (HDAC2 (show HDAC2 Proteins)) and Snail (show SNAI1 Proteins), which exerted a negative effect on p53 (show TP53 Proteins) expression in neoplastic cells; CAGE confers drug resistance by regulating expression of p53 (show TP53 Proteins) through HDAC2 (show HDAC2 Proteins).
CAGE promotes motility of cancer cells through activation of focal adhesion kinase (FAK).
This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family. Other members of this protein family participate in ATP-dependent RNA unwinding.
DEAD box protein 53
, DEAD-box protein CAGE
, cancer/testis antigen 26
, cancer-associated gene protein
, probable ATP-dependent RNA helicase DDX53
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
, probable ATP-dependent RNA helicase DDX53-like