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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) ELISA Kits

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. Additionally we are shipping DDX58 Antibodies (171) and DDX58 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DDX58 23586 O95786
DDX58 230073 Q6Q899
DDX58 297989  
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Top DDX58 ELISA Kits at antibodies-online.com

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Rabbit
96 Tests Log in to see 11 to 13 Days
$785.71
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Dog
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$999.43
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Guinea Pig
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$999.43
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Rat
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$999.43
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Monkey
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Rabbit
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$999.43
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Human
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More ELISA Kits for DDX58 Interaction Partners

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) interaction partners

  1. These findings collectively support the conclusion that IKK (show CHUK ELISA Kits) modulates innate immune signaling cascades via phosphorylating the RIG-I cytosolic sensor, providing a feedback regulatory mechanism.

  2. ATP hydrolysis displaces wild-type RIG-I from this self-RNA but not from 5' triphosphate dsRNA.

  3. that miR-4516 mediated down-regulation of UBE2N promotes p53 nuclear translocation and pro-apoptotic activity of PUVA is independent of IRF3 but is mediated by the RIG-I in a p53 and NFkappaB dependent manner

  4. Data show that the NS3 protein of dengue virus bound to 14-3-3 epsilon protein (14-3-3varepsilon) and prevented translocation of retinoic acid-inducible gene-I protein (RIG-I) to the adaptor MAVS (show MAVS ELISA Kits) protein and thereby blocked antiviral signaling.

  5. Data show that microRNA-136 (miRNA-136) antagonized H5N1 influenza A virus replication, and as an interleukin 6 (IL-6 (show IL6 ELISA Kits)) repressor, simultaneously as an immune trigger of retinoic acid-inducible gene 1 (show RARRES3 ELISA Kits) (RIG-I) signaling.

  6. These results showed that mRNA levels of MDA5 (show IFIH1 ELISA Kits) and RIG-1 (show RARRES3 ELISA Kits) were significantly decreased and increased, respectively, in chronic hepatitis B patients when compared to healthy controls.

  7. Data suggest that ppp-RNA orchestrating retinoic acid-inducible gene-I protein (RIG-I) activation to 5'-triphosphate siRNA targeting VEGF (show VEGFA ELISA Kits) (ppp-VEGF (show VEGFA ELISA Kits)) could be strategy for cancer therapy.

  8. RIG-I subsequently localized to antiviral stress granules induced after viral replication complexes formation

  9. HDAC6 (show HDAC6 ELISA Kits) transiently bound to RIG-I and removed the lysine 909 acetylation in the presence of viral RNAs, promoting RIG-I sensing of viral RNAs.

  10. RIG-I uses its autoinhibitory CARD2 (show KRT8 ELISA Kits)-Hel2i (second CARD-helicase insertion domain) interface as a barrier to select against non-blunt ended double-stranded RNAs.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) interaction partners

  1. RIG-I subsequently localized to antiviral stress granules induced after viral replication complexes formation

  2. identifies DDX58 and MTHFSD as two TDP-43 (show TARDBP ELISA Kits) targets that are misregulated in amyotrophic lateral sclerosis. 1

  3. Data show that preconditioning with poly(I:C) alters toll (show TLR4 ELISA Kits)-like receptors (TLR) and RIG-I-like receptors (RLRs) responses in opposite directions.

  4. Cytosolic LMW FGF2 (show FGF2 ELISA Kits) functions as a negative regulator in RIG-I-mediated antiviral signaling.

  5. results indicate that Lyn (show LYN ELISA Kits) plays a positive regulatory role in RIG-I-mediated interferon (show IFNA ELISA Kits) expression as a downstream component of IPS-1 (show ISYNA1 ELISA Kits)

  6. In lung epithelial cells, retinoic acid-inducible gene-1 (show RARRES3 ELISA Kits) (RIG-I) was identified as the major RIG-I-like receptor required for RSV-induced protease expression via MAVS (show MAVS ELISA Kits).

  7. findings suggest that RIG-I directs a typical IFN-dependent antiviral response against an RNA virus capable of suppressing the RNAi response

  8. The results describe a novel, interactive relationship between RIG-I downstream signalling molecules resulting in efficient anti-viral immunity.

  9. senses hepatitis B virus RNA, and counteracts HBV polymerase

  10. RIG-I-like receptor (RLR (show DHX58 ELISA Kits)) signaling pathway was significantly affected by Yersinia pestis infection

Pig (Porcine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) interaction partners

  1. Viral RNA polymerase components PB2, PB1, and PA directly target RIG-I.

  2. These data indicate that classical swine fever virus can be recognized by both RIG-I and MDA5 (show IFIH1 ELISA Kits) to initiate the RIG-I signaling pathway to trigger innate defenses against infection.

  3. DDX58 had two nonsynonymous SNPs in the helicase (show DNA2 ELISA Kits) domain.

DDX58 Antigen Profile

Antigen Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.

Gene names and symbols associated with DDX58

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (DDX58) antibody
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58) antibody
  • 6430573D20Rik antibody
  • C330021E21 antibody
  • RHIV-1 antibody
  • RIG-1 antibody
  • RIG-I antibody
  • RIGI antibody
  • RLR-1 antibody

Protein level used designations for DDX58

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I , probable ATP-dependent RNA helicase DDX58 , putative ATP-dependent RNA helicase DDX58 , retinoic acid-inducible protein I , DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 , probable ATP-dependent RNA helicase DDX58-like , DEAD box protein 58 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide , RIG-1 , RIG-I-like receptor 1 , RNA helicase RIG-I , retinoic acid inducible gene I , retinoic acid-inducible gene 1 protein , retinoic acid-inducible gene I protein , DEAD-box protein 58 , DEAD/H box polypeptide RIG-I , retinoic acid-inducible gene-I , RNA helicase induced by virus

GENE ID SPECIES
465035 Pan troglodytes
704638 Macaca mulatta
100067920 Equus caballus
100347707 Oryctolagus cuniculus
100408692 Callithrix jacchus
100443290 Pongo abelii
23586 Homo sapiens
230073 Mus musculus
297989 Rattus norvegicus
100686785 Canis lupus familiaris
396723 Sus scrofa
504760 Bos taurus
101107257 Ovis aries
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