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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DDX18 Antibodies (21) and many more products for this protein.
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In a zebrafish mutagenesis we identified an insertional allele hi1727, which disru (show BCL11A Proteins)pts the gene encoding RNA helicase dead-box 18 (Ddx18).
Data show that odulation of RNA helicase DDX18 directly affects growth of tamoxifen-resistant cells, suggesting that it may be a critical downstream effector of the estrogen receptors (ERs) and high mobility group box 2 (HMGB2 (show HMGB2 Proteins)) complex.
We identified 4 nonsynonymous sequence variants of DDX18 in acute myeloid leukemia (show BCL11A Proteins) patient samples
findings suggest that MrDb is important for cell proliferation and that its inhibition could prevent tumor cell proliferation.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein.
ATP-dependent RNA helicase DDX18
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
, ATP-dependent RNA helicase DDX18-like
, DEAD box protein 18
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated)
, Myc-regulated DEAD box protein