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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DDX4 Kits (18) and DDX4 Proteins (6) and many more products for this protein.
Showing 10 out of 85 products:
Human Monoclonal DDX4 Primary Antibody for IHC (f), WB - ABIN967664
Abdelhaleem: RNA helicases: regulators of differentiation. in Clinical biochemistry 2005
Show all 6 references for ABIN967664
Human Monoclonal DDX4 Primary Antibody for ICC, FACS - ABIN969084
Castrillon, Quade, Wang, Quigley, Crum: The human VASA gene is specifically expressed in the germ cell lineage. in Proceedings of the National Academy of Sciences of the United States of America 2000
Show all 4 references for ABIN969084
Human Monoclonal DDX4 Primary Antibody for EIA, IF - ABIN1106960
Zeeman, Stoop, Boter, Gillis, Castrillon, Oosterhuis, Looijenga: VASA is a specific marker for both normal and malignant human germ cells. in Laboratory investigation; a journal of technical methods and pathology 2002
Show all 4 references for ABIN1106960
Human Polyclonal DDX4 Primary Antibody for EIA, IHC (p) - ABIN356869
Guo, Gui, Tang, Lu, Gao, Cai: Differential expression of VASA gene in ejaculated spermatozoa from normozoospermic men and patients with oligozoospermia. in Asian journal of andrology 2007
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Chicken Polyclonal DDX4 Primary Antibody for IF (p) - ABIN701372
Imus, Roe, Charter, Durrant, Jensen: Transfer and detection of freshly isolated or cultured chicken (Gallus gallus) and exotic species' embryonic gonadal germ stem cells in host embryos. in Zoological science 2014
Data show that intrinsically disordered N terminus of DEAD-box RNA helicase (show DDX5 Antibodies) Ddx4 forms organelles in HeLa cells and in vitro.
this study reports the first analysis and comparison of the expression patterns and colocalization of DDX4 and CD133 in 59 ovarian cancer patients via tissue microarray and immunofluorescence analysis to identify the expression patterns and relationship of those two markers in ovarian cancer cells.
Data suggest that VASA shows differential expression in ovary; in resting primordial follicle reserve in childhood/pre-puberty, VASA is associated with Balbiani's body space in germ cell; once follicle enters growing pool, VASA is undetectable.
Vasa/Ddx4 gene can be involved in regulation of ground and primed states of pluripotency
overexpression of VASA and or DAZL (show DAZL Antibodies), in both embryonic and induced pluripotent stem cells promoted differentiation into primordial germ cells, and maturation and progression through meiosis was enhanced.
Report the generation/characterization of embryonic stem cell lines carrying a VASA-pEGFP-1 reporter construct that expresses GFP in a population of differentiating cells showing expression of characteristic markers of primordial germ cells.
The expression of VASA mRNA and protein was significantly decreased in the sperm of oligozoospermic men.
VASA showed a differential pattern of expression throughout the differentiation and proliferative phase and prophase I to finally associate with Balbiani's body in primordial and primary follicles.
Over-expression of VASA abrogates the G2 checkpoint, induced by DNA damage, by down-regulating the expression of 14-3-3sigma. Results suggest that VASA may play a role in the progression of ovarian cancer or serve as a valuable marker of tumorigenesis.
Highly methylated regions of the VASA gene are associated with maturation arrest phenotype in the testis.
In mouse oocytes the mitochondrion-originated germinal body-like structures accumulate MVH protein.
The results indicate the presence of a developmentally regulated mechanism in which Hat1 (show HAT1 Antibodies) and p46 (show POLDIP3 Antibodies) control the physiology of the chromatoid body by acetylation of MVH.
SPSB1 (show SPSB1 Antibodies) and SPSB4 bind strongly to both Par-4 (show F2RL3 Antibodies) and VASA peptides.
MVH plays crucial roles in the early phase of the ping-pong amplification cycle
The RNA helicase Vasa is another essential protein in germline development and arginine methylation is conserved across phyla
Data show that RanBPM (show RANBP9 Antibodies) and mouse vasa homolog (Mvh) are closely associated with perinuclear RNA-protein complexes and chromatoid bodies, and suggests a functional relationship between translational regulation and microtubule nucleation during meiosis.
Dazl (show DAZL Antibodies) stimulates translation via the Mvh 3'-UTR (show UTS2R Antibodies). Dazl (show DAZL Antibodies)-mediated regulation of Mvh translation is crucial for mammalian spermatogenesis
These results demonstrate that testicular cell-surface DDX4-immunoreactive cells are not germ cells and constitute a distinct subpopulation that is different from gonocytes.
Porcine Vasa Homolog (pvh) is specifically expressed in germ cell lineages, and can be a useful marker for germ cell development in pigs.
VASA was highly represented in the testis and the ovary, and still present in the oocyte from antral follicles.
The expression of VASA in bovine fetuses is reported.
The RNA helicase (show DDX46 Antibodies) Vasa is another essential protein in germline development and arginine methylation is conserved across phyla
XVLG1 protein in pPGC is not sufficient to increase the number of primordial germ cells in the tadpoles
Xdsg protein in pPGCs may play an important role in the formation of PGCs by regulating the production of XVLG1 protein
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
DEAD box protein 4
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4
, probable ATP-dependent RNA helicase DDX4
, vasa homolog
, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4
, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4
, DEAD box polypeptide 4
, mvh / m'vasa
, vasa-like protein
, putative ATP-dependent RNA helicase DDX4
, vasa-like gene protein