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DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 Proteins (DDX11)

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 Antibodies (67) and DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDX11 1663 Q96FC9
DDX11 320209 Q6AXC6
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Top DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

DDX11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11) Interaction Partners

Human DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11) interaction partners

  1. In this study, we found that cohesion establishment factors, like CHlR1, cooperatively stimulate endonuclease activity of hFen1 in in vivo mimic condition, including replication protein-A (show GPR153 Proteins)-coated DNA and high salt.

  2. DDX11 and Tim proteins physically and functionally interact and act in concert to preserve replication fork progression in perturbed conditions.

  3. Q Motif Is Involved in DNA Binding but Not ATP Binding in ChlR1 Helicase

  4. our results indicate that DDX11 functions as a positive regulator of rRNA transcription and provides a novel insight into the pathogenesis of WABS.

  5. A distinct triplex DNA unwinding activity of ChlR1 helicase.

  6. ChlR1 plays a critically important role in cellular replication and/or DNA repair. [review]

  7. Data indicate a homozygous mutation (c.788G>A [p.R263Q]) in DDX11 in three affected siblings with severe intellectual disability and many of the congenital abnormalities reported in the Warsaw breakage syndrome (WABS) original case.

  8. helicase DDX11 is expressed at high levels in primary and metastatic melanoma, and that interfering with its expression leads to severe chromosome segregation defects, telomere shortening, and massive melanoma cell apoptosis.

  9. The results identify novel roles of Ddx11 during embryo morphogenesis and demonstrate that the activity of its motif V is essential for DDX11 function.

  10. Wild-type ChlR1 required a minimal 5' single-stranded DNA tail of 15 nucleotides to efficiently unwind a simple duplex DNA substrate.

Mouse (Murine) DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11) interaction partners

  1. ChlR1 is essential for embryonic development and the prevention of aneuploidy in mammals.

DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11) Protein Profile

Protein Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with DDX11

  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (DDX11)
  • DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11)
  • DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (Ddx11)
  • 4732462I11Rik protein
  • CHL1 protein
  • CHLR1 protein
  • essa15a protein
  • KRG2 protein
  • WABS protein

Protein level used designations for DDX11

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) , CHL1-like helicase homolog , CHL1-related helicase gene-1 , CHL1-related protein 1 , DEAD/H box protein 11 , KRG-2 , hCHLR1 , keratinocyte growth factor-regulated gene 2 protein , probable ATP-dependent RNA helicase DDX11

GENE ID SPECIES
100448472 Pongo abelii
1663 Homo sapiens
320209 Mus musculus
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