You are viewing an incomplete version of our website. Please click to reload the website as full version.

DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 Proteins (DHX36)

DHX36 is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. Additionally we are shipping DHX36 Antibodies (34) and DHX36 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat DHX36 DHX36 310461  
DHX36 170506 Q9H2U1
DHX36 72162 Q8VHK9
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top DHX36 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 49 to 54 Days
Insect Cells Human GST tag   100 μg Log in to see 24 to 29 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

DHX36 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36) Interaction Partners

Human DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36) interaction partners

  1. RHAU binds to an adenosine-rich region near the 3'-end of the long non-coding RNA BC200.

  2. present a model showing that a replication fork disrupting a T-loop could create a 5' quadruplex with an opened 3'tail structure that is recognized by G4R1

  3. we identify a novel function of DHX36 to facilitate viral RNA recognition

  4. Used an integrated approach that includes small angle x-ray scattering, nuclear magnetic resonance spectroscopy, circular dichroism, and dynamic light scattering methods to demonstrate the recognition of G-quadruplexes by the N-terminal domain of RHAU.

  5. Data supports a helicase function of RHAU on an intramolecular RNA quadruplex and show that the enzyme is capable of completely converting quadruplex RNA to a stable duplex.

  6. Data show that hnRNPA1 (show HNRNPA1 Proteins)/A2, HuR (show ELAVL1 Proteins) and DAZAP1 (show DAZAP1 Proteins) splicing factors and DHX36 RNA helicase bind to the ISE, with hnRNPA1 (show HNRNPA1 Proteins) acting negatively and DAZAP1 (show DAZAP1 Proteins) positively on splicing selection

  7. The helicase domain of DHX36 does not mediate telomerase RNA (hTR) binding; instead, hTR interacts with the N-terminal accessory domain of DHX36 known to bind specifically to the parallel-strand G-quadruplex substrates resolved by the helicase domain.

  8. The amino-terminal region of RHAU is essential for RHAU to bind G4 structures and within this region the evolutionary conserved RSM (RHAU-specific motif) domain is a major affinity and specificity determinant

  9. DHX9/DHX36 represent the MyD88 (show MYD88 Proteins)-dependent DNA sensors in the cytosol of plasmacytoid dendritic cells and suggest a much broader role for DHX helicases in viral sensing

  10. DHX36 protein is responsible for the majority of tetramolecular G4-DNA resolvase activity

Mouse (Murine) DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36) interaction partners

  1. The ablation of RHAU in germ cells caused the increase of G4 structures and thus resulted in the decrease of spermatogonial differentiation.

  2. RHAU deletion in hematopoietic system caused hemolytic anemia and differentiation defect at the proerythroblast stage. RHAU may play a role in the regulation of gene expression that relies on its G4 resolvase activity.

  3. DDX1 (show DDX1 Proteins)-DDX21 (show DDX21 Proteins)-DHX36 complex represents a dsRNA sensor that uses the TRIF (show RNF138 Proteins) pathway to activate type I IFN responses in the cytosol of myeloid dendritic cells

DHX36 Protein Profile

Protein Summary

This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with DHX36

  • DEAH (Asp-Glu-Ala-His) box polypeptide 36 (Dhx36)
  • DEAH (Asp-Glu-Ala-His) box polypeptide 36 (DHX36)
  • DEAH (Asp-Glu-Ala-His) box polypeptide 36 (dhx36)
  • 2810407E23Rik protein
  • AI452301 protein
  • AU022184 protein
  • Ddx36 protein
  • DHX57 protein
  • G4R1 protein
  • mKIAA1488 protein
  • MLEL1 protein
  • RHAU protein

Protein level used designations for DHX36

probable ATP-dependent RNA helicase DHX36 , DEAH (Asp-Glu-Ala-His) box polypeptide 36 , probable ATP-dependent RNA helicase DHX36-like , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36 , DEAH box protein 36 , G4 resolvase-1 , MLE-like protein 1 , RNA helicase associated with AU-rich element ARE

310461 Rattus norvegicus
425032 Gallus gallus
460791 Pan troglodytes
477117 Canis lupus familiaris
509583 Bos taurus
708112 Macaca mulatta
100012581 Monodelphis domestica
100355806 Oryctolagus cuniculus
100389011 Callithrix jacchus
100481192 Ailuropoda melanoleuca
100495115 Xenopus (Silurana) tropicalis
100456222 Pongo abelii
100547484 Meleagris gallopavo
100626674 Sus scrofa
100633205 Amphimedon queenslandica
170506 Homo sapiens
72162 Mus musculus
Selected quality suppliers for DHX36 Proteins (DHX36)
Did you look for something else?