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ATP-binding RNA helicase involved in translation initiation. Additionally we are shipping DHX29 Proteins (3) and many more products for this protein.
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DHX29 and eIF3 (show EIF3A Antibodies) cooperate in scanning on structured mRNAs. Our findings support previous genetic data on the role of eIF3 (show EIF3A Antibodies) during scanning
DHX29 is another example of an initiation factor contributing to start codon selection.
Helicase proteins DHX29 and RIG-I (show DDX58 Antibodies) cosense cytosolic nucleic acids in the human airway system.
Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs.
Down-regulation of DHX29 leads to impaired translation, resulting in disassembly of polysomes and accumulation of mRNA-free 80S monomers. DHX29 depletion also impedes cancer cell growth in culture and in xenografts.
Study reports that these 7 eIFs are not sufficient for efficient 48S complex formation on mRNAs with highly structured 5'UTRs, and that this process requires the DExH-box protein DHX29.
ATP-binding RNA helicase involved in translation initiation. Required for efficient initiation on mammalian mRNAs with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation (By similarity).
DEAH (Asp-Glu-Ala-His) box polypeptide 29
, ATP-dependent RNA helicase DHX29-like
, ATP-dependent RNA helicase DHX29
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29
, DEAH box protein 29
, nucleic acid helicase DDXx
, ATP-dependent RNA helicase Dhx29