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anti-DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3) Antibodies

DIRAS3 is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. Additionally we are shipping DIRAS3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DIRAS3 9077 O95661
DIRAS3    
DIRAS3    
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Top anti-DIRAS3 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB DIRAS3 Antibody (ABIN652072) western blot analysis in WiDr cell line lysates (35 µg/lane). This demonstrates the DIRAS3 antibody detected the DIRAS3 protein (arrow). DIRAS3 Antibody (ABIN652072) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-ARHI Polyclonal Antibody, Unconjugated (ABIN681448) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of DIRAS3 expression in transfected 293T cell line by DIRAS3 monoclonal antibody (M01A), clone 1G4.Lane 1: DIRAS3 transfected lysate (Predicted MW: 25.9 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (36.74 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IP, ELISA, WB 100 μg Log in to see 8 to 10 Days
$581.17
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details

DIRAS3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,
,
, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-DIRAS3 Antibodies

  1. Human Polyclonal DIRAS3 Primary Antibody for ELISA, WB - ABIN563932 : Li, Ramani, Sun, Zee, Grant, Yang, Xia, Oh, Ko, Mato, Lu: Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice. in The American journal of pathology 2010 (PubMed)

More Antibodies against DIRAS3 Interaction Partners

Pig (Porcine) DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3) interaction partners

  1. polymorphism-based approach was used to detect the imprinting status of NNAT (show NNAT Antibodies) and DIRAS3 genes in five heterozygous pigs (based on SNP) of Large White and Meishan F(1) hybrids

Human DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3) interaction partners

  1. Transcriptional, but not post-transcriptional, silencing of GNG12-AS1 (show PTGDR Antibodies) causes concomitant upregulation of DIRAS3, indicating a function in transcriptional interference.

  2. ARHI mRNA and protein expression is markedly decreased in osteosarcoma MG-63 cells lines. Overexpression of ARHI inhibits cell viability and proliferation.

  3. ARHI-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts.

  4. EZH2 (show EZH2 Antibodies)-''induced H3K27me3 is associated with epigenetic repression of the ARHI tumor-suppressor gene in epithelial ovarian cancer

  5. ARHI competes with RanGTPase and interacts with importin beta (show KPNB1 Antibodies) via basic-acidic patch interaction, which leads to inhibition of STAT3 (show STAT3 Antibodies) translocation.

  6. Letter: ARHI suppresses pancreatic cancer by regulating ERK 1 (show MAPK3 Antibodies)/2 signaling.

  7. JMJD2A (show KDM4A Antibodies)-dependent silencing of Sp1 (show PSG1 Antibodies) in advanced breast cancer promotes metastasis by downregulation of DIRAS3.

  8. suggest that DIRAS3 not only regulates the autophagosome initiation complex, but induces autophagy in dormant, nutrient-deprived ovarian cancer cells that remain after conventional chemotherapy, facilitating their survival

  9. ARHI is required for autophagy-meditated cancer cell arrest and ARHI inhibits signaling through PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and Ras/MAP by enhancing internalization and degradation of the epidermal growth factor receptor (show EGFR Antibodies).

  10. The silence of ARHI expression in vitro seems to accelerate the malignant transformation of healthy ovarian cells by restraining apoptosis and autophagy.

DIRAS3 Antigen Profile

Protein Summary

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

Gene names and symbols associated with DIRAS3

  • DIRAS family, GTP-binding RAS-like 3 (DIRAS3) antibody
  • DIRAS family, GTP-binding RAS-like 3 (diras3) antibody
  • ARHI antibody
  • DIRAS3 antibody
  • NOEY2 antibody

Protein level used designations for DIRAS3

DIRAS family, GTP-binding RAS-like 3 , GTP-binding protein Di-Ras3 , GTP-binding RAS-like protein 3 , distinct subgroup of the Ras family member 3 , ras homolog gene family, member I , rho-related GTP-binding protein RhoI

GENE ID SPECIES
456930 Pan troglodytes
504559 Bos taurus
701273 Macaca mulatta
733668 Sus scrofa
100135197 Xenopus (Silurana) tropicalis
100147791 Ovis aries
9077 Homo sapiens
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