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DIX Domain Containing 1 (DIXDC1) ELISA Kits

The protein encoded by DIXDC1 is a positive regulator of the Wnt signaling pathway and interacts with AXIN1, DVL2, and MAP3K1. Additionally we are shipping DIX Domain Containing 1 Antibodies (44) and DIX Domain Containing 1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DIXDC1 85458 Q155Q3
DIXDC1 330938 Q80Y83
DIXDC1 363062 Q2VUH7
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Top DIX Domain Containing 1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Rat
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$875.60
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Human
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$875.60
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More ELISA Kits for DIX Domain Containing 1 Interaction Partners

Human DIX Domain Containing 1 (DIXDC1) interaction partners

  1. DIXDC1 was overexpressed in gastric cancer and correlated with poor prognosis.

  2. DIXDC1 is associated with stage and prognosis in non-small cell lung cancer, and may promote invasion and migration through PI3K (show PIK3CA ELISA Kits)-AKT (show AKT1 ELISA Kits)/AP-1 (show FOSB ELISA Kits)-dependent activation of metalloproteinases

  3. DIXDC1 depletion results in upregulation of Snail1 (show SNAI1 ELISA Kits) in a FAK (show PTK2 ELISA Kits)-dependent manner, leading to increased cell invasion. MARK1 (show MARK1 ELISA Kits) phosphorylation of DIXDC1 is required for its localization to focal adhesions and ability to suppress metastasis in mice.

  4. Transgenic DIXDC1 might contribute to pathophysiology underlying abnormal behaviors in sch (show DISC1 ELISA Kits)izophrenia and other major psychiatric disorders in mice.

  5. a molecular mechanism for Ccd1 (show RUNX2 ELISA Kits)-mediated Wnt (show WNT2 ELISA Kits) activation in that Ccd1 (show RUNX2 ELISA Kits) converts latent polymeric Dvl (show DVL2 ELISA Kits) to a biologically active oligomer(s).

  6. This study reveal that Dixdc1 integrates DISC1 (show DISC1 ELISA Kits) into Wnt (show WNT2 ELISA Kits)-GSK3beta/beta-catenin (show CTNNB1 ELISA Kits)-dependent and -independent signaling pathways during cortical development and further delineate how DISC1 (show DISC1 ELISA Kits) contributes to neuropsychiatric disorders.

  7. Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway activation might upregulate DIXDC1 through a post-translational mechanism by inhibiting the ubiquitin-mediated degradation of the DIXDC1 protein.

  8. MTHDIX (KIAA1735) protein consists of Myosine-tail homologous (MTH) domain and C-terminal DIX domain.

  9. Ccd1 (show RUNX2 ELISA Kits) inhibits Axin (show AXIN1 ELISA Kits)-mediated JNK (show MAPK8 ELISA Kits) activation by simultaneously adopting two distinct mechanisms, one through conformational changes that disallow MEKK1 (show MAP3K1 ELISA Kits) binding and the other via direct sequestration of MEKK4 (show MAP3K4 ELISA Kits).

  10. Thus, our data provide the first evidence that l-DIXDC1 may act as a novel branching component in the Wnt signaling pathway targeting both beta-catenin-TCF complex for gene expression and cytoskeleton for regulating dynamics of actin filaments.

Mouse (Murine) DIX Domain Containing 1 (DIXDC1) interaction partners

  1. Abnormal behavior in Dixdc1 mice could elucidate molecular pathophysiology involving Disc1 (show DISC1 ELISA Kits) in major mental illnesses.

  2. crystals of the Ccd1 DIX domain belonged to space group P2(1)2(1)2(1), with unit-cell parameters a=72.9, b=75.7, c=125.6 A. An X-ray diffraction data set was collected at 3.0 A resolution

  3. a molecular mechanism for Ccd1-mediated Wnt (show WNT2 ELISA Kits) activation in that Ccd1 converts latent polymeric Dvl (show DVL1 ELISA Kits) to a biologically active oligomer(s).

  4. DIXDC1 encodes a novel protein with a myosine-tail homologous domain and C-terminal DIX domain

  5. mouse Ccd1 functions as a positive regulator of the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway. Furthermore, Ccd1 is highly expressed and co-localized with Wnt (show WNT2 ELISA Kits) signaling molecules in the embryonic and adult brain.

Zebrafish DIX Domain Containing 1 (DIXDC1) interaction partners

  1. These results indicate that Ccd1 is a novel positive regulator in this Wnt (show WNT2 ELISA Kits) signaling pathway during zebrafish neural patterning.

DIX Domain Containing 1 (DIXDC1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a positive regulator of the Wnt signaling pathway and interacts with AXIN1, DVL2, and MAP3K1. The encoded protein is found associated with gamma tubulin at the centrosome. Three transcript variants, two protein-coding and the other non-protein coding, have been found for this gene. The longer isoform also associates with actin stress fibers while the shorter isoform does not.

Gene names and symbols associated with DIXDC1

  • DIX domain containing 1 (DIXDC1) antibody
  • DIX domain containing 1 (dixdc1) antibody
  • DIX domain containing 1 (Dixdc1) antibody
  • DIX domain containing 1a (dixdc1a) antibody
  • DIX domain containing 1b (dixdc1b) antibody
  • 4930563F16Rik antibody
  • BC048182 antibody
  • ccd1 antibody
  • Ccd1Aalpha1L antibody
  • Ccd1Abeta1L antibody
  • Ccd1BalphaL antibody
  • Ccd1BbetaL antibody
  • Ccd1CL antibody
  • dixdc1 antibody
  • im:7138279 antibody
  • mKIAA1735 antibody

Protein level used designations for DIXDC1

DIX domain containing 1 , dixin-like , coiled-coil protein DIX1 , dixin , DIX domain-containing protein 1 , coiled-coil-DIX1 , DIX domain-containing protein 1-A , coiled-coil DIX 1 , coiled-coil protein DIX1-A , coiled-coil-DIX1-A , dixin-A

GENE ID SPECIES
419798 Gallus gallus
466779 Pan troglodytes
710847 Macaca mulatta
100032288 Monodelphis domestica
100061990 Equus caballus
100225366 Taeniopygia guttata
100349631 Oryctolagus cuniculus
100411324 Callithrix jacchus
100462633 Pongo abelii
100497786 Xenopus (Silurana) tropicalis
100548570 Meleagris gallopavo
100581393 Nomascus leucogenys
85458 Homo sapiens
608957 Canis lupus familiaris
541211 Bos taurus
330938 Mus musculus
363062 Rattus norvegicus
360137 Danio rerio
794716 Danio rerio
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