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DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Proteins (DMC1)

The protein encoded by DMC1 is essential for meiotic homologous recombination. Additionally we are shipping DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Antibodies (102) and DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DMC1 13404 Q61880
DMC1 11144 Q14565
Rat DMC1 DMC1 362960  
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Top DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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DMC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) Interaction Partners

Mouse (Murine) DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) interaction partners

  1. The DMC1 was highly variable from cell to cell, whereas foci of the crossover marker MLH1 (show MLH1 Proteins) showed little variability.

  2. RAD51AP1 (show RAD51AP1 Proteins) foci colocalize with a subset of DMC1 foci in spermatocytes.

  3. p53 (show TP53 Proteins) might be involved in homologous recombination and/or checkpoint function by directly binding to DMC1 protein to repress genomic instability in meiotic germ cells

  4. TBPIP/HOP2 (show PSMC3IP Proteins) directly binds to DNA and functions as an activator for DMC1 during the homologous pairing step in meiosis

  5. data reveal an interplay among Hop2 (show PSMC3IP Proteins), Mnd1 (show MND1 Proteins) and Rad51 (show RAD51 Proteins) and Dmc1 in the formation of the first recombination intermediates during meiosis

  6. Mei1 (show MEI1 Proteins) can be positioned upstream of Dmc1 in the genetic pathway that operates during mammalian meiosis

  7. Dmc1(Mei11) exposes a sex difference in recombination in that a significant portion of female oocytes can compensate for DMC1 deficiency to undergo crossing-over and complete gametogenesis.

Human DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) interaction partners

  1. BRCA2 (show BRCA2 Proteins) protein stimulates DMC1-mediated DNA strand exchange between RPA (show RPA1 Proteins)-ssDNA complexes and duplex DNA, thus identifying BRCA2 (show BRCA2 Proteins) as a mediator of DMC1 recombination function.

  2. Dmc1 can reject divergent DNA sequences while bypassing a few mismatches in the DNA sequence.

  3. In contrast to RAD51 (show RAD51 Proteins), stabilization of the presynaptic filament via ATP hydrolysis attenuation is insufficient for enhancement of the DMC1-catalyzed recombination reaction.

  4. truncated DMC1 octamers further stack with alternate polarity into a filament

  5. results suggested mutations in the coding sequence of DMC1 are not associated with premature ovarian failure in Chinese women

  6. The results suggested that PSF (show IGFBP7 Proteins) may function as an activator for the meiosis-specific recombinase (show RAG1 Proteins) DMC1.

  7. RAD51-associated protein 1 (RAD51AP1 (show RAD51AP1 Proteins)) interacts with the meiotic recombinase (show RAG1 Proteins) DMC1 through a conserved motif.

  8. RAD51AP1 (show RAD51AP1 Proteins) foci colocalize with a subset of DMC1 foci in spermatocytes.

  9. D-loops in a human DMC1-driven reaction are substantially more resistant to dissociation by branch-migration proteins such as RAD54 (show ATRX Proteins) than those formed by RAD51 (show RAD51 Proteins).

  10. the Dmc1 filament formed on single-stranded DNA has a mass per unit length expected from approximately 6.5 subunits per turn

DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) Protein Profile

Protein Summary

The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined.

Gene names and symbols associated with DMC1

  • DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) (DMC1)
  • DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) (dmc1)
  • DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (Dmc1)
  • DNA meiotic recombinase 1 (DMC1)
  • DNA meiotic recombinase 1 (Dmc1)
  • DCM1 protein
  • dJ199H16.1 protein
  • DMC1 protein
  • DMC1H protein
  • LIM15 protein
  • Mei11 protein
  • sgdp protein
  • zgc:136628 protein

Protein level used designations for DMC1

DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) , RecA homolog Dmc1 , disrupted meiotic cDNA 1 , meiotic recombination protein DMC1/LIM15 homolog , meiotic recombination protein DMC1/LIM15 homolog-like , meiotic recombination protein dmc1/lim15-like protein , disrupted meiotic cDNA 1 homolog , DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination , disrupted meiotic cDNA1, yeast, homolog of

GENE ID SPECIES
458831 Pan troglodytes
553953 Danio rerio
608268 Canis lupus familiaris
100055204 Equus caballus
100408835 Callithrix jacchus
100473602 Ailuropoda melanoleuca
100528115 Ictalurus punctatus
100013547 Monodelphis domestica
100579935 Nomascus leucogenys
13404 Mus musculus
427903 Gallus gallus
100522866 Sus scrofa
618398 Bos taurus
11144 Homo sapiens
362960 Rattus norvegicus
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