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DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) ELISA Kits

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Additionally we are shipping DNA (Cytosine-5)-Methyltransferase 1 Antibodies (387) and DNA (Cytosine-5)-Methyltransferase 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNMT1 1786 P26358
DNMT1 84350  
DNMT1 13433 P13864
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Top DNA (Cytosine-5)-Methyltransferase 1 ELISA Kits at

Showing 7 out of 18 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Pulldown of Dnmt1 using the Dnmt1-Trap:  Immunoprecipitations (IP) of ... On cell lysate: HEK 293T and HeLa lysate (size DNMT1: 183 kDa). Diluti... 250 μL Log in to see 4 to 5 Days
Pulldown of Dnmt1 using the Dnmt1-Trap:  Immunoprecipitations (IP) of ... On cell lysate: HEK 293T and HeLa lysate (size DNMT1: 183 kDa). Diluti... 20 Tests Log in to see 4 to 5 Days
Human 0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 0.053 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Rat 0.09 ng/mL 0.16-10 ng/mL   96 Tests Log in to see 8 to 9 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days

Top referenced DNA (Cytosine-5)-Methyltransferase 1 ELISA Kits

  1. ABIN1082202 : Qin, Leonhardt, Pichler: Regulation of DNA methyltransferase 1 by interactions and modifications. in Nucleus (Austin, Tex.) 2011 (PubMed)

More ELISA Kits for DNA (Cytosine-5)-Methyltransferase 1 Interaction Partners

Zebrafish DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 stability requires UHRF1 (show UHRF1 ELISA Kits) phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  2. Lsh (show HELLS ELISA Kits) Is Essential for Maintaining Global DNA Methylation (show HELLS ELISA Kits) Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

  3. Dnmt1 is required for hematopoietic stem and progenitor cells maintenance via cebpa (show CEBPA ELISA Kits) regulation during definitive hematopoiesis in zebrafish

  4. These data provide the first evidence that Uhrf1 (show UHRF1 ELISA Kits) and Dnmt1 function is required for vertebrate lens development and maintenance.

  5. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 (show SUV39H1 ELISA Kits) and that, together, Dnmt1 and Suv39h1 (show SUV39H1 ELISA Kits) help guide the terminal differentiation of particular tissues.

  6. Data show that in dnmt1 homozygous mutants, reactivation of gfp expression occurs in a reproducible subset of cells, raising the possibility of different sensitivities or alternative silencing mechanisms in discrete cell populations.

  7. Thus, our data suggest that Dnmt1 is dispensable for pancreatic duct or endocrine cell formation, but not for acinar cell survival. In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors.

Human DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Results show that miR (show MLXIP ELISA Kits)-148a is down-regulated in urothelial cell carcinoma of the bladder cell lines. Its overexpression leads to induction of apoptosis in part by down-regulating DNMT1.

  2. These data suggest that targeting the IL-8 (show IL8 ELISA Kits)/AKT1 (show AKT1 ELISA Kits) signaling pathway and DNMT1 may provide a potential therapeutic approach for blocking NPC (show NPC1 ELISA Kits) metastasis.

  3. miR (show MLXIP ELISA Kits)-140-5p at least partly targets Dnmt1 and regulates SOD2 (show SOD2 ELISA Kits) expression to inhibit proliferation and promote apoptosis and differentiation of HPASMCs in hypoxia

  4. Data indicate an epigenetic prognostic signature in glioblastomas based on expression of polycomb (show CBX2 ELISA Kits) repressive complex 2 (EZH2 (show EZH2 ELISA Kits)), DNA-methyltransferases DNMT1 and 3B which can be used easily in routine neuropathology practice.

  5. the abundance of BDNF (show BDNF ELISA Kits) positively correlated and phosphorylated DNMT1 inversely correlated with that of FKBP51 (show FKBP4 ELISA Kits) in cells

  6. miR (show MLXIP ELISA Kits)-124 and miR (show MLXIP ELISA Kits)-506 inhibit progression and increase sensitivity to chemotherapy by targeting DNMT3B (show DNMT3B ELISA Kits) and DNMT1 in colorectal carcinoma.

  7. To correlate DNMTs expression with DNA methylation (show HELLS ELISA Kits), DNMT1, DNMT3A (show DNMT3A ELISA Kits) and DNMT3B (show DNMT3B ELISA Kits) mRNA levels in 5 colorectal cancer cell lines; results suggest that cellular DNMT expression is positively correlated with global DNA methylation (show HELLS ELISA Kits) level but not with regional DNA hypermethylation at each locus.

  8. Phosphorylated p38 (show CRK ELISA Kits), DNMT1 and AChE were aberrantly expressed in a subset of hepatocellular carcinoma tumors.

  9. We further demonstrate that such fibroblast activation is dependent on phosphate influx, aberrant phosphorylation of DNA methyltransferase DNMT1 and aberrant CpG island promoter methylation.

  10. The subangstrom geometric and electrostatic structure of the major transition state of the reaction catalyzed by human DNMT1 is presented. The rate-limiting methyl transfer occurs after Cys (show DNAJC5 ELISA Kits)(1226) attack to Cyt (show CYGB ELISA Kits) C6.

Pig (Porcine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 was indispensable for oocyte cytoplasmic maturation, providing a novel role for Dnmt1 in the regulation of oocyte maturation.

  2. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a (show DNMT3A ELISA Kits), Hdac1 (show HDAC1 ELISA Kits), Kdm3a (show KDM3A ELISA Kits) and Uhrf1 (show UHRF1 ELISA Kits) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

  3. DNMT1o is localized mainly in the nuclei of oocytes and early embryos, whereas DNMT1s is expressed in the ooplasm (show NLRP5 ELISA Kits) cortex of oocytes and cytoplasm of early embryos.

  4. results indicate that loss of Dnmt1 in the maternal nucleus during SCNT significantly contributes to the unfaithful maintenance of methylation imprints in cloned embryos

  5. Oocyte-specific Dnmt1 is cytoplasmic during early development.

  6. Dnmt1 mRNA abundance plays an important role during protein regulation, Dnmt1 enzyme is mainly posttranscriptionally regulated.

Cow (Bovine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Through down-regulating the expression of DNMT1, miR (show MYLIP ELISA Kits)-152 reduced Global DNA methylation (show HELLS ELISA Kits) and the activity of DNMT to reactivate the lactation signal transduction genes Akt (show AKT1 ELISA Kits) and Ppar gamma (show PPARG ELISA Kits).

  2. More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 ELISA Kits) mRNA was present at highest levels in transgenic SCNT embryos.

  3. Our results indicate an essential role for Dnmt1 during bovine preimplantation development (show MTA2 ELISA Kits), and suggest proper transcriptional reprogramming of this gene family in SCNT embryos.

  4. Dnmt1 is retained in the cytoplasm in metaphase II stage oocytes and zygotes, it enters the nuclei of 8-16 cell stage embryos

  5. Abnormal gene expression of DNMT, INFT, and MHC1 was noted in the majority of cloned embryos, indicating inefficient nuclear reprogramming and retarded embryo development.

  6. Results describe the alternative splicing and expression analysis of bovine DNA methyltransferase 1.

  7. Report inhibition of DNA methyltransferase 1 expression in bovine fibroblast cells used for nuclear transfer.

Arabidopsis thaliana DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. MET1 is a thylakoid-associated TPR protein involved in photosystem II supercomplex formation and repair in Arabidopsis

  2. Met1 gene expression throughout normal development, particularly in the flower

  3. MET1 is a contributor to epigenetic diversity in Arabidopsis.

  4. VIM (show VIM ELISA Kits) proteins regulate genome-wide epigenetic gene silencing through coordinated modulation of DNA methylation (show HELLS ELISA Kits) and histone modification status in collaboration with MET1

  5. VIM (show VIM ELISA Kits) proteins function in transcriptional regulation via their roles in the MET1 DNA methylation (show HELLS ELISA Kits) pathway.

  6. Genetic studies indicate that the Polycomb (show CBX2 ELISA Kits) Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. [MET1]

  7. MET1 restores body methylation, which is region-specific but random with respect to the affected CG sites, and is moderately although not decisively influenced by transcription.

  8. There is a mechanistic link between two major epigenetic pathways involved in histone and DNA methylation (show HELLS ELISA Kits) in plants by physical interaction of MET1 with the FIS-PRC2 core component MEA.

  9. Our results bear interesting similarities with cancer cells, which show global losses of DNA methylation (show HELLS ELISA Kits) but ectopic hypermethylation of genes previously marked by H3K27m3.

  10. An intergenic nucleosome-free crossover hotspot 3a undergoes increased recombination activity in met1.

Mouse (Murine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. the abundance of BDNF (show BDNF ELISA Kits) positively correlated and phosphorylated DNMT1 inversely correlated with that of FKBP51 (show FKBP5 ELISA Kits) in cells

  2. we suggest that 14-3-3 (show YWHAQ ELISA Kits) is a crucial reader of DNMT1pSer143 that regulates DNA methylation (show HELLS ELISA Kits) and altered gene expression that contributes to cell invasion

  3. The replication foci targeting sequence domain, not the proliferating cell nuclear antigen (show PCNA ELISA Kits) - binding domain, is solely responsible for the replication-coupled DNA methylation (show HELLS ELISA Kits).

  4. The expression of DNMT1 and DNMT3b (show DNMT3B ELISA Kits) was decreased at 1 mT, and 50 Hz ELF (show SPTBN1 ELISA Kits)-EMF can increase the expression...the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF (show SPTBN1 ELISA Kits)-EMF exposure

  5. Data suggest Fabp4 (show FABP4 ELISA Kits) is up-regulated and DNA methylation (show HELLS ELISA Kits) is down-regulated in aorta in hyperhomocysteinemia induced by high-methionine diet; up-regulation of DNA methyltransferase 1 (Dnmt1) promotes DNA methylation (show HELLS ELISA Kits) and decreases Fabp4 (show FABP4 ELISA Kits) expression.

  6. Obesity-induced, pro-inflammatory cytokines promote DNMT1 expression and its hypermethylation of the adiponectin (show ADIPOQ ELISA Kits) promoter, suppressing adiponectin (show ADIPOQ ELISA Kits) expression and exacerbating insulin (show INS ELISA Kits) resistance.

  7. Dnmt1 is indispensable for mammary stem cell and mammary cancer stem cell maintenance, and for mammary tumorigenesis. Dnmt1 hypermethylates and downregulates ISL1 (show ISL1 ELISA Kits) in mammary tumors and cancer stem cells.

  8. The hypermethylation of KLF4 (show KLF4 ELISA Kits) directly mediated by Dnmt1 contributes to the progression of EMT (show ITK ELISA Kits) in renal epithelial cells.

  9. the presence of DNMT1 in adult neural stem/precursor cells is crucial for the survival of newly generated neurons, but is dispensable once they accomplish neuronal differentiation in the adult hippocampus.

  10. Data suggest that Dnmt1 deficiency leads to increased placental triacylglycerol accumulation, abnormal placental mitochondria form/function, and fetal growth retardation; metabolism in the embryo appears unaffected in other parameters investigated.

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antigen Profile

Antigen Summary

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DNMT1

  • DNA (cytosine-5-)-methyltransferase 1 (DNMT1) antibody
  • DNA (cytosine-5-)-methyltransferase 1 (dnmt1) antibody
  • DNA (cytosine-5-)-methyltransferase 1 (Dnmt1) antibody
  • DNA (cytosine-5)-methyltransferase 1 (MET1) antibody
  • DNA methyltransferase (cytosine-5) 1 (Dnmt1) antibody
  • ADCADN antibody
  • AIM antibody
  • cb983 antibody
  • cb1075 antibody
  • Cxxc9 antibody
  • DDM2 antibody
  • dmnt1 antibody
  • DMT01 antibody
  • DMT1 antibody
  • Dnmt antibody
  • Dnmt1o antibody
  • fb05h01 antibody
  • HSN1E antibody
  • m.MmuI antibody
  • MCMT antibody
  • Met-1 antibody
  • Met1 antibody
  • MET2 antibody
  • methyltransferase 1 antibody
  • METI antibody
  • MommeD2 antibody
  • mta antibody
  • MTase antibody
  • wu:fb05h01 antibody

Protein level used designations for DNMT1

DNA (cytosine-5)-methyltransferase 1 , ddn , CXXC-type zinc finger protein 9 , DNA MTase HsaI , DNA methyltransferase HsaI , m.HsaI , DNA methyltransferase 1 , DNA (cytosine 5 ) methyltransferase 1 , DNA methyltransferase (cytosine 5 ) methyltransferase , DNA methyltransferase b , DNA MTase RnoIP , DNA methyltransferase (cytosine-5) 1 , DNA methyltransferase I , MCMT , m.RnoIP , DNA MTase GgaI , DNA MeTase , DNA methyltransferase GgaI , m.GgaI , DNA MTase MmuI , DNA methyltransferase MmuI

443549 Ovis aries
30430 Danio rerio
1786 Homo sapiens
476715 Canis lupus familiaris
606746 Sus scrofa
281119 Bos taurus
84350 Rattus norvegicus
396011 Gallus gallus
834975 Arabidopsis thaliana
13433 Mus musculus
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