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DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) ELISA Kits

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Additionally we are shipping DNA (Cytosine-5)-Methyltransferase 1 Antibodies (436) and DNA (Cytosine-5)-Methyltransferase 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNMT1 1786 P26358
DNMT1 84350  
DNMT1 13433 P13864
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Top DNA (Cytosine-5)-Methyltransferase 1 ELISA Kits at antibodies-online.com

Showing 7 out of 23 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human
Pulldown of Dnmt1 using the Dnmt1-Trap:  Immunoprecipitations (IP) of Dnmt1 from a protein extract of HEK 293T cells. Size of DNMT1: 186 kDA. Primary antibody: anti-DNMT1 1:500. Secondary antibody: anti-rat 1:2000. Input (I), non-bound (FT) and bound (B) fractions were separated by SDS-PAGE followed by Coomassie staining and Western Blotting. Unlike conventional antibodies, the Dnmt1-Trap is free from heavy and/or light chain contaminants and therefore yields cleaner results. On cell lysate: HEK 293T and HeLa lysate (size DNMT1: 183 kDa). Dilution 1:500. Secondary antibody: anti-rat 647. Please note that the Dnmt1 antibody is not working with recombinant DNMT1. 250 μL Log in to see 4 to 5 Days
$295.31
Details
Human
Pulldown of Dnmt1 using the Dnmt1-Trap:  Immunoprecipitations (IP) of Dnmt1 from a protein extract of HEK 293T cells. Size of DNMT1: 186 kDA. Primary antibody: anti-DNMT1 1:500. Secondary antibody: anti-rat 1:2000. Input (I), non-bound (FT) and bound (B) fractions were separated by SDS-PAGE followed by Coomassie staining and Western Blotting. Unlike conventional antibodies, the Dnmt1-Trap is free from heavy and/or light chain contaminants and therefore yields cleaner results. On cell lysate: HEK 293T and HeLa lysate (size DNMT1: 183 kDa). Dilution 1:500. Secondary antibody: anti-rat 647. Please note that the Dnmt1 antibody is not working with recombinant DNMT1. 20 Tests Log in to see 4 to 5 Days
$459.38
Details
Human 0.057 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 0.053 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Rat 0.059 ng/mL 0.15-10 ng/mL   96 Tests Log in to see 9 to 11 Days
$800.00
Details
Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Chicken
  96 Tests Log in to see 11 to 13 Days
$1,095.60
Details

Top referenced DNA (Cytosine-5)-Methyltransferase 1 ELISA Kits

  1. Human DNMT1 Primary Antibody for AM, ChIP - ABIN1082202 : Qin, Leonhardt, Pichler: Regulation of DNA methyltransferase 1 by interactions and modifications. in Nucleus (Austin, Tex.) 2011 (PubMed)

More ELISA Kits for DNA (Cytosine-5)-Methyltransferase 1 Interaction Partners

Zebrafish DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 stability requires UHRF1 (show UHRF1 ELISA Kits) phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  2. Lsh (show HELLS ELISA Kits) Is Essential for Maintaining Global DNA Methylation (show HELLS ELISA Kits) Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

  3. Dnmt1 is required for hematopoietic stem and progenitor cells maintenance via cebpa (show CEBPA ELISA Kits) regulation during definitive hematopoiesis in zebrafish

  4. These data provide the first evidence that Uhrf1 (show UHRF1 ELISA Kits) and Dnmt1 function is required for vertebrate lens development and maintenance.

  5. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 (show SUV39H1 ELISA Kits) and that, together, Dnmt1 and Suv39h1 (show SUV39H1 ELISA Kits) help guide the terminal differentiation of particular tissues.

  6. Data show that in dnmt1 homozygous mutants, reactivation of gfp expression occurs in a reproducible subset of cells, raising the possibility of different sensitivities or alternative silencing mechanisms in discrete cell populations.

  7. Thus, our data suggest that Dnmt1 is dispensable for pancreatic duct or endocrine cell formation, but not for acinar cell survival. In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors.

Human DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Sequence analysis results of a family with a family with adult-onset autosomal dominant cerebellar ataxia (show USP14 ELISA Kits) with deafness and narcolepsy identified a variant, NM_001130823.1:c.1709C>T [p.Ala570Val], in DNMT1 gene which was segregated with the disease within the family. These findings provide evidence that this heterozygous variant is likely disease-causing pathogenesis.

  2. Overexpression of DNMT1 gene in the liver has been found after one dose of dibutyl phthalate, which was confirmed at the protein level by Western blot analysis.

  3. The role of DNMT1 single nucleotide polymorphism rs16999593 in patients with transposition of great arteries in the Southern Chinese population

  4. DNMT1, DNMT3A (show DNMT3A ELISA Kits) and DNMT3B (show DNMT3B ELISA Kits) are highly expressed in human medulloblastoma samples

  5. Significant upregulation of DNMT1, DNMT3A (show DNMT3A ELISA Kits), and DNMT3B (show DNMT3B ELISA Kits) expression was found in para-carcinoma tissues, compared with the histopathologically unchanged tissues furthermore, distinguishable expression profiling was observed of target miRNAs in tissues with different distance

  6. A potential role of rs2424913 (DNMT3B (show DNMT3B ELISA Kits)) and rs2228611 (DNMT1) in autoimmune thyroid diseases (AITD) susceptibility and identified novel gene-gene/gene-sex interactions in AITD. This may highlight sex and genes of DNMTs family as contributors to the pathogenesis of AITD.

  7. Considering the observation that decreased expression level of DNMT1 was associated with hypermethylation of DNMT1 promoter in ankylosing spondylitis patients, this survey suggests that dysregulation of DNMT1 expression through altered methylation level of other target genes would probably contribute to ankylosing spondylitis development.

  8. mRNA and protein expression levels of DNMT1 were upregulated in genotype 1b and 3a HCV-infected hepatocellular carcinoma patients as compared to control. No differences were seen for genotypes 5 and 7.

  9. Overexpression of DNMT1 is associated with Hepatocellular Carcinoma.

  10. Our meta-analysis suggested that DNMT1 rs16999593 and DNMT3A (show DNMT3A ELISA Kits) rs1550117 could contribute to GC and that DNMT3B (show DNMT3B ELISA Kits) rs1569686 might function as a protective factor against gastric carcinogenesis.

Pig (Porcine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 was indispensable for oocyte cytoplasmic maturation, providing a novel role for Dnmt1 in the regulation of oocyte maturation.

  2. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a (show DNMT3A ELISA Kits), Hdac1 (show HDAC1 ELISA Kits), Kdm3a (show KDM3A ELISA Kits) and Uhrf1 (show UHRF1 ELISA Kits) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

  3. DNMT1o is localized mainly in the nuclei of oocytes and early embryos, whereas DNMT1s is expressed in the ooplasm (show NLRP5 ELISA Kits) cortex of oocytes and cytoplasm of early embryos.

  4. results indicate that loss of Dnmt1 in the maternal nucleus during SCNT significantly contributes to the unfaithful maintenance of methylation imprints in cloned embryos

  5. Oocyte-specific Dnmt1 is cytoplasmic during early development.

  6. Dnmt1 mRNA abundance plays an important role during protein regulation, Dnmt1 enzyme is mainly posttranscriptionally regulated.

Cow (Bovine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. DNMT1 silencing significantly decreased the methylation levels of miR (show MYLIP ELISA Kits)-29b promoter, up-regulated miR (show MYLIP ELISA Kits)-29b expression and inhibited bovine viral diarrhea virus replication.

  2. Through down-regulating the expression of DNMT1, miR (show MYLIP ELISA Kits)-152 reduced Global DNA methylation (show HELLS ELISA Kits) and the activity of DNMT to reactivate the lactation signal transduction genes Akt (show AKT1 ELISA Kits) and Ppar gamma (show PPARG ELISA Kits).

  3. More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 ELISA Kits) mRNA was present at highest levels in transgenic SCNT embryos.

  4. Our results indicate an essential role for Dnmt1 during bovine preimplantation development (show MTA2 ELISA Kits), and suggest proper transcriptional reprogramming of this gene family in SCNT embryos.

  5. Dnmt1 is retained in the cytoplasm in metaphase II stage oocytes and zygotes, it enters the nuclei of 8-16 cell stage embryos

  6. Abnormal gene expression of DNMT, INFT, and MHC1 was noted in the majority of cloned embryos, indicating inefficient nuclear reprogramming and retarded embryo development.

  7. Results describe the alternative splicing and expression analysis of bovine DNA methyltransferase 1.

  8. Report inhibition of DNA methyltransferase 1 expression in bovine fibroblast cells used for nuclear transfer.

Arabidopsis thaliana DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. MET1 is a thylakoid-associated TPR protein involved in photosystem II supercomplex formation and repair in Arabidopsis

  2. Met1 gene expression throughout normal development, particularly in the flower

  3. MET1 is a contributor to epigenetic diversity in Arabidopsis.

  4. VIM (show VIM ELISA Kits) proteins regulate genome-wide epigenetic gene silencing through coordinated modulation of DNA methylation (show HELLS ELISA Kits) and histone modification status in collaboration with MET1

  5. VIM (show VIM ELISA Kits) proteins function in transcriptional regulation via their roles in the MET1 DNA methylation (show HELLS ELISA Kits) pathway.

  6. Genetic studies indicate that the Polycomb (show CBX2 ELISA Kits) Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. [MET1]

  7. MET1 restores body methylation, which is region-specific but random with respect to the affected CG sites, and is moderately although not decisively influenced by transcription.

  8. There is a mechanistic link between two major epigenetic pathways involved in histone and DNA methylation (show HELLS ELISA Kits) in plants by physical interaction of MET1 with the FIS-PRC2 core component MEA.

  9. Our results bear interesting similarities with cancer cells, which show global losses of DNA methylation (show HELLS ELISA Kits) but ectopic hypermethylation of genes previously marked by H3K27m3.

  10. An intergenic nucleosome-free crossover hotspot 3a undergoes increased recombination activity in met1.

Mouse (Murine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. miR (show MLXIP ELISA Kits)-29a mimic transfection lowered collagen 1alpha1, DNMT1, DNMT3b (show DNMT3B ELISA Kits) and SET1A (show SETD1A ELISA Kits) expression in hepatic stellate cells.

  2. These results demonstrate that Dnmt1 and Dnmt3b (show DNMT3B ELISA Kits) cooperate to maintain DNA methylation (show HELLS ELISA Kits) and genomic integrity in the intestinal epithelium.

  3. DNMT1 mRNA expression was significantly decreased in the isocortex but significantly increased in the prefrontal following hyperoxia

  4. Cigarette smoke induces proteosomal-mediated degradation of DNMT1 in embryonic orofacial cells.

  5. the abundance of BDNF (show BDNF ELISA Kits) positively correlated and phosphorylated DNMT1 inversely correlated with that of FKBP51 (show FKBP5 ELISA Kits) in cells

  6. we suggest that 14-3-3 (show YWHAQ ELISA Kits) is a crucial reader of DNMT1pSer143 that regulates DNA methylation (show HELLS ELISA Kits) and altered gene expression that contributes to cell invasion

  7. The replication foci targeting sequence domain, not the proliferating cell nuclear antigen (show PCNA ELISA Kits) - binding domain, is solely responsible for the replication-coupled DNA methylation (show HELLS ELISA Kits).

  8. The expression of DNMT1 and DNMT3b (show DNMT3B ELISA Kits) was decreased at 1 mT, and 50 Hz ELF (show SPTBN1 ELISA Kits)-EMF can increase the expression...the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF (show SPTBN1 ELISA Kits)-EMF exposure

  9. Data suggest Fabp4 (show FABP4 ELISA Kits) is up-regulated and DNA methylation (show HELLS ELISA Kits) is down-regulated in aorta in hyperhomocysteinemia induced by high-methionine diet; up-regulation of DNA methyltransferase 1 (Dnmt1) promotes DNA methylation (show HELLS ELISA Kits) and decreases Fabp4 (show FABP4 ELISA Kits) expression.

  10. Obesity-induced, pro-inflammatory cytokines promote DNMT1 expression and its hypermethylation of the adiponectin (show ADIPOQ ELISA Kits) promoter, suppressing adiponectin (show ADIPOQ ELISA Kits) expression and exacerbating insulin (show INS ELISA Kits) resistance.

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antigen Profile

Antigen Summary

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DNMT1

  • DNA (cytosine-5-)-methyltransferase 1 (DNMT1) antibody
  • DNA (cytosine-5-)-methyltransferase 1 (dnmt1) antibody
  • DNA (cytosine-5-)-methyltransferase 1 (Dnmt1) antibody
  • DNA (cytosine-5)-methyltransferase 1 (MET1) antibody
  • DNA methyltransferase (cytosine-5) 1 (Dnmt1) antibody
  • ADCADN antibody
  • AIM antibody
  • cb983 antibody
  • cb1075 antibody
  • Cxxc9 antibody
  • DDM2 antibody
  • DECREASED DNA METHYLATION 2 antibody
  • dmnt1 antibody
  • DMT01 antibody
  • DMT1 antibody
  • DNA METHYLTRANSFERASE antibody
  • DNA METHYLTRANSFERASE 01 antibody
  • DNA METHYLTRANSFERASE 1 antibody
  • Dnmt antibody
  • Dnmt1o antibody
  • fb05h01 antibody
  • HSN1E antibody
  • m.MmuI antibody
  • MCMT antibody
  • Met-1 antibody
  • Met1 antibody
  • MET2 antibody
  • methyltransferase 1 antibody
  • METHYLTRANSFERASE 2 antibody
  • METHYLTRANSFERASE I antibody
  • METI antibody
  • MommeD2 antibody
  • mta antibody
  • MTase antibody
  • wu:fb05h01 antibody

Protein level used designations for DNMT1

DNA (cytosine-5)-methyltransferase 1 , ddn , CXXC-type zinc finger protein 9 , DNA MTase HsaI , DNA methyltransferase HsaI , m.HsaI , DNA methyltransferase 1 , DNA (cytosine 5 ) methyltransferase 1 , DNA methyltransferase (cytosine 5 ) methyltransferase , DNA methyltransferase b , DNA MTase RnoIP , DNA methyltransferase (cytosine-5) 1 , DNA methyltransferase I , MCMT , m.RnoIP , DNA MTase GgaI , DNA MeTase , DNA methyltransferase GgaI , m.GgaI , DNA MTase MmuI , DNA methyltransferase MmuI

GENE ID SPECIES
443549 Ovis aries
30430 Danio rerio
1786 Homo sapiens
476715 Canis lupus familiaris
606746 Sus scrofa
281119 Bos taurus
84350 Rattus norvegicus
396011 Gallus gallus
834975 Arabidopsis thaliana
13433 Mus musculus
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