DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) ELISA Kits

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Additionally we are shipping DNA (Cytosine-5)-Methyltransferase 1 Antibodies (431) and DNA (Cytosine-5)-Methyltransferase 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNMT1 1786 P26358
DNMT1 84350  
DNMT1 13433 P13864
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Top DNA (Cytosine-5)-Methyltransferase 1 ELISA Kits at antibodies-online.com

Showing 7 out of 24 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human
Pulldown of Dnmt1 using the Dnmt1-Trap:  Immunoprecipitations (IP) of Dnmt1 from a protein extract of HEK 293T cells. Size of DNMT1: 186 kDA. Primary antibody: anti-DNMT1 1:500. Secondary antibody: anti-rat 1:2000. Input (I), non-bound (FT) and bound (B) fractions were separated by SDS-PAGE followed by Coomassie staining and Western Blotting. Unlike conventional antibodies, the Dnmt1-Trap is free from heavy and/or light chain contaminants and therefore yields cleaner results. On cell lysate: HEK 293T and HeLa lysate (size DNMT1: 183 kDa). Dilution 1:500. Secondary antibody: anti-rat 647. Please note that the Dnmt1 antibody is not working with recombinant DNMT1. 250 μL Log in to see 5 to 6 Days
$295.31
Details
Human
Pulldown of Dnmt1 using the Dnmt1-Trap:  Immunoprecipitations (IP) of Dnmt1 from a protein extract of HEK 293T cells. Size of DNMT1: 186 kDA. Primary antibody: anti-DNMT1 1:500. Secondary antibody: anti-rat 1:2000. Input (I), non-bound (FT) and bound (B) fractions were separated by SDS-PAGE followed by Coomassie staining and Western Blotting. Unlike conventional antibodies, the Dnmt1-Trap is free from heavy and/or light chain contaminants and therefore yields cleaner results. On cell lysate: HEK 293T and HeLa lysate (size DNMT1: 183 kDa). Dilution 1:500. Secondary antibody: anti-rat 647. Please note that the Dnmt1 antibody is not working with recombinant DNMT1. 20 Tests Log in to see 5 to 6 Days
$459.38
Details
Human 0.057 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details
Mouse 0.053 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$606.32
Details
Rat 0.059 ng/mL 0.15-10 ng/mL   96 Tests Log in to see 13 to 16 Days
$640.00
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details
Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

Top referenced DNA (Cytosine-5)-Methyltransferase 1 ELISA Kits

  1. ABIN1082202 : Qin, Leonhardt, Pichler: Regulation of DNA methyltransferase 1 by interactions and modifications. in Nucleus (Austin, Tex.) 2011 (PubMed)

More ELISA Kits for DNA (Cytosine-5)-Methyltransferase 1 Interaction Partners

Zebrafish DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 stability requires UHRF1 (show UHRF1 ELISA Kits) phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  2. Lsh (show HELLS ELISA Kits) Is Essential for Maintaining Global DNA Methylation (show HELLS ELISA Kits) Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

  3. Dnmt1 is required for hematopoietic stem and progenitor cells maintenance via cebpa (show CEBPA ELISA Kits) regulation during definitive hematopoiesis in zebrafish

  4. These data provide the first evidence that Uhrf1 (show UHRF1 ELISA Kits) and Dnmt1 function is required for vertebrate lens development and maintenance.

  5. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 (show SUV39H1 ELISA Kits) and that, together, Dnmt1 and Suv39h1 (show SUV39H1 ELISA Kits) help guide the terminal differentiation of particular tissues.

  6. Data show that in dnmt1 homozygous mutants, reactivation of gfp expression occurs in a reproducible subset of cells, raising the possibility of different sensitivities or alternative silencing mechanisms in discrete cell populations.

  7. Thus, our data suggest that Dnmt1 is dispensable for pancreatic duct or endocrine cell formation, but not for acinar cell survival. In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors.

Human DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. MUC1 (show MUC1 ELISA Kits)-C is of functional importance to induction of DNMT1 and DNMT3b (show DNMT3B ELISA Kits) and, in turn, changes in DNA methylation (show HELLS ELISA Kits) patterns in cancer cells.

  2. This study demonstrates novel regulatory circuits involving miR (show MLXIP ELISA Kits)-148a-3p/ERBB3 (show ERBB3 ELISA Kits)/AKT2 (show AKT2 ELISA Kits)/c-myc (show MYC ELISA Kits) and DNMT1 that controls bladder cancer progression, which may be useful in the development of more effective therapies against bladder cancer.

  3. a novel molecular mechanism by which MBD4 (show MBD4 ELISA Kits) inhibits GITR (show TNFRSF18 ELISA Kits) expression in a DNMT1-dependent manner

  4. a model in which the EZH2 (show EZH2 ELISA Kits)/HOXA11 (show HOXA11 ELISA Kits)-AS/LSD1 (show KDM1A ELISA Kits) complex and HOXA11 (show HOXA11 ELISA Kits)-AS/miR (show MLXIP ELISA Kits)-1297/EZH2 (show EZH2 ELISA Kits) cross-talk serve as critical effectors in gastric cancer tumorigenesis and progression.

  5. Studies indicate that DNA methylation (show HELLS ELISA Kits) is mediated by three DNA (Cytosine-5-)-Methyltransferase (DNMTs): DNMT1 is responsible for the maintenance of methylation patterns after DNA replication whereas DNMT3A (show DNMT3A ELISA Kits) and DNMT3B (show DNMT3B ELISA Kits) carry out de novo methylation, and DNMT inhibitors have showed promising results in clinical trials of prostate cancer.

  6. Our results suggest that epigenetic alteration of histone demethylation regulated by reduction of DNMT1 may control induction of EMT (show ITK ELISA Kits) and the CSC phenotype, which facilitates tumorigenesis in PCa (show FLVCR1 ELISA Kits) cells and has important therapeutic implications in targeting epigenetic regulation.

  7. results indicated that the age and total cholesterol concentrations were independent influential factors of ChREBP (show MLXIPL ELISA Kits) methylation and DNMT1 variants could probably influence LDL-C to further modify ChREBP (show MLXIPL ELISA Kits) DNA methylation (show HELLS ELISA Kits)

  8. DNMT1 overexpression is associated with Breast Cancer.

  9. Data suggest that epigenetic changes in histone acetylation and DNA methylation (show HELLS ELISA Kits) may contribute to the repression of RGS2 (regulator of G-protein signaling 2 (show RGS2 ELISA Kits)) expression in chemo-resistant ovarian cancer cells; regulation of HDAC1 (histone deacetylase 1 (show HDAC1 ELISA Kits)) and DNMT1 (DNA methyltransferase 1) contribute to the suppression of RGS2 (show RGS2 ELISA Kits).

  10. Arx (show UBA2 ELISA Kits) and Dnmt1 that are sufficient for achieving targeted generation of beta cells from adult pancreatic alpha cells.

Pig (Porcine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 was indispensable for oocyte cytoplasmic maturation, providing a novel role for Dnmt1 in the regulation of oocyte maturation.

  2. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a (show DNMT3A ELISA Kits), Hdac1 (show HDAC1 ELISA Kits), Kdm3a (show KDM3A ELISA Kits) and Uhrf1 (show UHRF1 ELISA Kits) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

  3. DNMT1o is localized mainly in the nuclei of oocytes and early embryos, whereas DNMT1s is expressed in the ooplasm (show NLRP5 ELISA Kits) cortex of oocytes and cytoplasm of early embryos.

  4. results indicate that loss of Dnmt1 in the maternal nucleus during SCNT significantly contributes to the unfaithful maintenance of methylation imprints in cloned embryos

  5. Oocyte-specific Dnmt1 is cytoplasmic during early development.

  6. Dnmt1 mRNA abundance plays an important role during protein regulation, Dnmt1 enzyme is mainly posttranscriptionally regulated.

Cow (Bovine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. DNMT1 silencing significantly decreased the methylation levels of miR (show MYLIP ELISA Kits)-29b promoter, up-regulated miR (show MYLIP ELISA Kits)-29b expression and inhibited bovine viral diarrhea virus replication.

  2. Through down-regulating the expression of DNMT1, miR (show MYLIP ELISA Kits)-152 reduced Global DNA methylation (show HELLS ELISA Kits) and the activity of DNMT to reactivate the lactation signal transduction genes Akt (show AKT1 ELISA Kits) and Ppar gamma (show PPARG ELISA Kits).

  3. More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 ELISA Kits) mRNA was present at highest levels in transgenic SCNT embryos.

  4. Our results indicate an essential role for Dnmt1 during bovine preimplantation development (show MTA2 ELISA Kits), and suggest proper transcriptional reprogramming of this gene family in SCNT embryos.

  5. Dnmt1 is retained in the cytoplasm in metaphase II stage oocytes and zygotes, it enters the nuclei of 8-16 cell stage embryos

  6. Abnormal gene expression of DNMT, INFT, and MHC1 was noted in the majority of cloned embryos, indicating inefficient nuclear reprogramming and retarded embryo development.

  7. Results describe the alternative splicing and expression analysis of bovine DNA methyltransferase 1.

  8. Report inhibition of DNA methyltransferase 1 expression in bovine fibroblast cells used for nuclear transfer.

Arabidopsis thaliana DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. MET1 is a thylakoid-associated TPR protein involved in photosystem II supercomplex formation and repair in Arabidopsis

  2. Met1 gene expression throughout normal development, particularly in the flower

  3. MET1 is a contributor to epigenetic diversity in Arabidopsis.

  4. VIM (show VIM ELISA Kits) proteins regulate genome-wide epigenetic gene silencing through coordinated modulation of DNA methylation (show HELLS ELISA Kits) and histone modification status in collaboration with MET1

  5. VIM (show VIM ELISA Kits) proteins function in transcriptional regulation via their roles in the MET1 DNA methylation (show HELLS ELISA Kits) pathway.

  6. Genetic studies indicate that the Polycomb (show CBX2 ELISA Kits) Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. [MET1]

  7. MET1 restores body methylation, which is region-specific but random with respect to the affected CG sites, and is moderately although not decisively influenced by transcription.

  8. There is a mechanistic link between two major epigenetic pathways involved in histone and DNA methylation (show HELLS ELISA Kits) in plants by physical interaction of MET1 with the FIS-PRC2 core component MEA.

  9. Our results bear interesting similarities with cancer cells, which show global losses of DNA methylation (show HELLS ELISA Kits) but ectopic hypermethylation of genes previously marked by H3K27m3.

  10. An intergenic nucleosome-free crossover hotspot 3a undergoes increased recombination activity in met1.

Mouse (Murine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. indispensable role of DNMT1-mediated epigenetic regulation in postnatal liver growth and regeneration

  2. SETDB1 (show SETDB1 ELISA Kits) maintains silencing of intracisternal A particle, but in the absence of DNMT1, prolonged binding of NP95 (show UHRF1 ELISA Kits) to hemimethylated DNA transiently disrupts SETDB1 (show SETDB1 ELISA Kits)-dependent H3K9me3 deposition.

  3. Arx and Dnmt1 that are sufficient for achieving targeted generation of beta cells from adult pancreatic alpha cells.

  4. The results of this study showed that DNA Methyltransferase 1 is main role of Development of the Hippocampal Dentate Gyrus in mice.

  5. three DNA methyltransferases, Dnmt1, Dnmt3a (show DNMT3A ELISA Kits), and Dnmt3b (show DNMT3B ELISA Kits), have been identified. Dnmt3a (show DNMT3A ELISA Kits) and Dnmt3b (show DNMT3B ELISA Kits) are responsible for establishing DNA methylation (show HELLS ELISA Kits) patterns produced through their de novo-type DNA methylation (show HELLS ELISA Kits) activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l (show TRDMT1 ELISA Kits)), which is a member of the Dnmt3 family but does not possess DNA methylation (show HELLS ELISA Kits)

  6. While lens epithelial cell survival requires DNMT1, morphologically normal lenses develop in the absence of both DNMT3A (show DNMT3A ELISA Kits) and DNMT3B (show DNMT3B ELISA Kits).

  7. Our results provide insights into the molecular basis of DNMT1 dysfunction in hereditary sensory and autonomic neuropathies with dementia and hearing loss patients and emphasize the importance of the TS domain in the regulation of DNA methylation (show HELLS ELISA Kits) in pluripotent and differentiating cells

  8. miR (show MLXIP ELISA Kits)-29a mimic transfection lowered collagen 1alpha1, DNMT1, DNMT3b (show DNMT3B ELISA Kits) and SET1A (show SETD1A ELISA Kits) expression in hepatic stellate cells.

  9. These results demonstrate that Dnmt1 and Dnmt3b (show DNMT3B ELISA Kits) cooperate to maintain DNA methylation (show HELLS ELISA Kits) and genomic integrity in the intestinal epithelium.

  10. DNMT1 mRNA expression was significantly decreased in the isocortex but significantly increased in the prefrontal following hyperoxia

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antigen Profile

Antigen Summary

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DNMT1

  • DNA (cytosine-5-)-methyltransferase 1 (DNMT1) antibody
  • DNA (cytosine-5-)-methyltransferase 1 (dnmt1) antibody
  • DNA (cytosine-5-)-methyltransferase 1 (Dnmt1) antibody
  • DNA (cytosine-5)-methyltransferase 1 (MET1) antibody
  • DNA methyltransferase (cytosine-5) 1 (Dnmt1) antibody
  • ADCADN antibody
  • AIM antibody
  • cb983 antibody
  • cb1075 antibody
  • Cxxc9 antibody
  • DDM2 antibody
  • DECREASED DNA METHYLATION 2 antibody
  • dmnt1 antibody
  • DMT01 antibody
  • DMT1 antibody
  • DNA METHYLTRANSFERASE antibody
  • DNA METHYLTRANSFERASE 01 antibody
  • DNA METHYLTRANSFERASE 1 antibody
  • Dnmt antibody
  • Dnmt1o antibody
  • fb05h01 antibody
  • HSN1E antibody
  • m.MmuI antibody
  • MCMT antibody
  • Met-1 antibody
  • Met1 antibody
  • MET2 antibody
  • methyltransferase 1 antibody
  • METHYLTRANSFERASE 2 antibody
  • METHYLTRANSFERASE I antibody
  • METI antibody
  • MommeD2 antibody
  • mta antibody
  • MTase antibody
  • wu:fb05h01 antibody

Protein level used designations for DNMT1

DNA (cytosine-5)-methyltransferase 1 , ddn , CXXC-type zinc finger protein 9 , DNA MTase HsaI , DNA methyltransferase HsaI , m.HsaI , DNA methyltransferase 1 , DNA (cytosine 5 ) methyltransferase 1 , DNA methyltransferase (cytosine 5 ) methyltransferase , DNA methyltransferase b , DNA MTase RnoIP , DNA methyltransferase (cytosine-5) 1 , DNA methyltransferase I , MCMT , m.RnoIP , DNA MTase GgaI , DNA MeTase , DNA methyltransferase GgaI , m.GgaI , DNA MTase MmuI , DNA methyltransferase MmuI

GENE ID SPECIES
443549 Ovis aries
30430 Danio rerio
1786 Homo sapiens
476715 Canis lupus familiaris
606746 Sus scrofa
281119 Bos taurus
84350 Rattus norvegicus
396011 Gallus gallus
834975 Arabidopsis thaliana
13433 Mus musculus
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