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anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Antibodies

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Additionally we are shipping DNMT3B Proteins (5) and DNMT3B Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DNMT3B 1789 Q9UBC3
DNMT3B 444985  
DNMT3B 13436 O88509
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Top anti-DNMT3B Antibodies at antibodies-online.com

Showing 10 out of 123 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DNMT3B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: OVCAR-3 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: DNMT3B  Gene Name: Anonymous Submitted by: 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Dnmt3b Pab (ABIN387884) in T47-D cell lysate. Dnmt3b (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HT-29 cells, using DNMT3B Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using DNMT3B Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ChIP, IHC, IHC (p), SimWes, WB Immunohistochemistry-Paraffin: DNMT3B Antibody [ABIN152675] - Analysis showing positive staining in the nucleus and cytoplasm of Mouse brain tissue (right) compared with a negative control in the absence of primary antibody (left). Western Blot: DNMT3B Antibody [ABIN152675] - Homogenized mouse brain cells. Image from verified customer review. 0.1 mg Log in to see 7 to 9 Days
$447.56
Details
Human Mouse Un-conjugated ChIP, CyTOF, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IHC (wm), IP, SimWes, WB Western blot analysis for Dnmt3b using ABIN252478 at 2 ug/ml against 10 µg of cell lysates of 293 transfected with mouse Dnmt3a (lane 1) and Dnmt3b (lane 2). A protein band of approximate mol. wt. of 110 kDa is only detected in 293 cells transfected with mouse Dnmt3b cDNA. Western blot analysis of Dnmt3b in NIH 3T3 cell lysate using ABIN252478 at 4 ug/ml. 0.1 mg Log in to see 7 to 9 Days
$473.81
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$315.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded: human colon cancer tissue labeled with Anti-Dnmt-3-beta Polyclonal Antibody, Unconjugated (ABIN727623) at 1:600, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded: rat spinal cord tissue labeled with Anti-Dnmt-3-beta Polyclonal Antibody (ABIN727623), Unconjugated at 1:600, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Un-conjugated ChIP, WB DNMT3B mAb tested by Western blot. Detection of DNMT3B by Western blot. The analysis was performed using DNMT3B mAb at a 2 µg/ml dilution and whole-cell extracts from 293 cells that had been transfected with plasmid expressing either mouse DNMT3A (lane A) or DNMT3B (lane B). 100 μg Log in to see 1 to 2 Days
$495.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IP, IHC, WB Western blot analysis using ABIN151734 to detect overexpressed DNMT-38 in HCT116 cells. Lane 1: 40 ug of nuclear extract from untransfected T24 cells. Lane 2-3: 40 ug of nuclear extracts transiently transfected to overexpress DNMT3B2 and DNMT3B3, respectively. Immunohistochemistry: Dnmt3b Antibody [ABIN151734] - Dnmt3b antibody was tested in mouse testis using DAB with hematoxylin counterstain. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details

DNMT3B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DNMT3B Antibodies

  1. Human Monoclonal DNMT3B Primary Antibody for ChIP, CyTOF - ABIN252478 : Santoro, Li, Grummt: The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. in Nature genetics 2002 (PubMed)
    Show all 97 references for ABIN252478

  2. Human Polyclonal DNMT3B Primary Antibody for ICC, IF - ABIN151734 : Robert, Morin, Beaulieu, Gauthier, Chute, Barsalou, MacLeod: DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. in Nature genetics 2003 (PubMed)
    Show all 15 references for ABIN151734

  3. Human Polyclonal DNMT3B Primary Antibody for IHC (p), WB - ABIN387884 : Lu, Markowetz, Unwin, Leek, Airoldi, MacArthur, Lachmann, Rozov, Maayan, Boyer, Troyanskaya, Whetton, Lemischka: Systems-level dynamic analyses of fate change in murine embryonic stem cells. in Nature 2009 (PubMed)
    Show all 13 references for ABIN387884

  4. Human Polyclonal DNMT3B Primary Antibody for ChIP, IHC - ABIN152675 : Okano, Bell, Haber, Li: DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. in Cell 1999 (PubMed)
    Show all 6 references for ABIN152675

  5. Human Monoclonal DNMT3B Primary Antibody for ChIP, WB - ABIN2668954 : Castro, Breiling, Luetkenhaus, Ceteci, Hausmann, Kress, Lyko, Rudel, Rapp: MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma. in Molecular cancer research : MCR 2013 (PubMed)
    Show all 2 references for ABIN2668954

  6. Human Polyclonal DNMT3B Primary Antibody for IF (p), IHC (p) - ABIN727623 : Zhao, Hou, Chen, Shao, Zhu, Bu, Gu, Li, Zhang, Du, Fu, Kong, Luo, Long, Li, Deng, Zhao, Cen: Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation. in Neurobiology of disease 2015 (PubMed)
    Show all 2 references for ABIN727623

  7. Human Polyclonal DNMT3B Primary Antibody for EIA, IHC (p) - ABIN356569 : Stipani, Cappello, Daddabbo, Natuzzi, Miniero, Stipani, Palmieri: The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents. in Biochemistry 2001 (PubMed)

  8. Human Polyclonal DNMT3B Primary Antibody for IF, IHC - ABIN1534163 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  9. Cow (Bovine) Polyclonal DNMT3B Primary Antibody for WB - ABIN2783648 : Boland, Christman: Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA. in Journal of molecular biology 2008 (PubMed)

More Antibodies against DNMT3B Interaction Partners

Zebrafish DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. dnmt7 specifically methylates no tail gene in the genome

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation (show HELLS Antibodies) content are rather a function of time, and not a genetic component.

Human DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. data indicated that Kaempferol is a novel DNMT3B inhibitor, which may promote the degradation of DNMT3B in bladder cancer.

  2. TLR9 (show TLR9 Antibodies) upregulation in cases with episomal HPV16 was again higher among those with non-methylated immunostimulatory CpG motifs. Comparison of cases with HPV-negative controls revealed that DNMT3A (show DNMT3A Antibodies) was significantly downregulated only among integrated cases, DNMT3B was significantly overexpressed among both categories of cases, although at variable levels, while DNMT1 (show DNMT1 Antibodies) failed to show any deregulated expression among the cases

  3. age affects the expression of DNMT1 (show DNMT1 Antibodies) and DNMT3B as an almost independent variable in respect of all other variables evaluated.

  4. Findings suggest that PTEN and DNMT3B possess common regulation features as well as certain ethnic differences in expression between Han women and Uygur women.

  5. This condensed chromatin structure is associated with binding of DNMT3B and decreased occupancy of OCT1 (show POU2F1 Antibodies) transcription factor at MAML2 (show MAML2 Antibodies) enhancer, suggesting a role of DNMT3B in increasing methylation of MAML2 (show MAML2 Antibodies) after stilbenoid treatment.

  6. show that heterozygous mutations in DNA methyltransferase 3B (DNMT3B) are a likely cause of D4Z4 derepression associated with low levels of DUX4 expression

  7. The de novo methyltransferases DNMT3A (show DNMT3A Antibodies) and 3B play a vital role in methylating the genome of the developing embryo in regions devoid of methylation marks.These observations suggest a potential interaction of G-quadruplexes with the DNA methylation (show HELLS Antibodies) machinery, which may be of epigenetic and biological significance

  8. 149C>T and -2437T>A DNMT3B polymorphisms are not correlated with lung cancer risk among Chinese population nor the haplotype of them.

  9. DNMT1 (show DNMT1 Antibodies), DNMT3A (show DNMT3A Antibodies) and DNMT3B are highly expressed in human medulloblastoma samples

  10. The DNMT3A (show DNMT3A Antibodies) -448A > G polymorphism may be a novel functional SNP and contribute to its genetic susceptibility to spontaneous abortion in Chinese women, and ART may not affect the distribution of -448A > G in pregnancy loss and normal pregnancy. The observed TT genotype of DMNT3B suggests that this is the predominant genotype of this population

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. The epiblast expressed epithelial markers, MUC1 (show MUC1 Antibodies) and E-CADHERIN (show CDH1 Antibodies), and the pluripotency markers, DNMT3B and CRIPTO (show TDGF1 Antibodies).

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.

  2. The expression levels of DNMT3a (show DNMT3A Antibodies) and DNMT3b were associated with several beef quality traits.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. While lens epithelial cell survival requires DNMT1 (show DNMT1 Antibodies), morphologically normal lenses develop in the absence of both DNMT3A (show DNMT3A Antibodies) and DNMT3B.

  2. Mechanical stimulation regulates osteoblastic genes expression via direct regulation of Dnmt3b.

  3. a miR (show MLXIP Antibodies)-125b-DNMT3b-p53 (show TP53 Antibodies) signal pathway may exist in the vascular smooth muscle cells proliferation induced by homocysteine.

  4. miR (show MLXIP Antibodies)-29a mimic transfection lowered collagen 1alpha1, DNMT1 (show DNMT1 Antibodies), DNMT3b and SET1A (show SETD1A Antibodies) expression in hepatic stellate cells.

  5. Loss of DNMT3B results in hypomethylation of the miR (show MLXIP Antibodies)-196b promoter and increased miR (show MLXIP Antibodies)-196b expression, which directly targets the mTORC2 (show CRTC2 Antibodies) component Rictor (show RICTOR Antibodies).

  6. The findings define PRMT7 (show PRMT7 Antibodies) as a regulator of the DNMT3b/p21 (show D4S234E Antibodies) axis required to maintain muscle stem cell regenerative capacity.

  7. These results demonstrate that Dnmt1 (show DNMT1 Antibodies) and Dnmt3b cooperate to maintain DNA methylation (show HELLS Antibodies) and genomic integrity in the intestinal epithelium.

  8. Downregulation of DNMT3B, one of the targets identified using this method, radiosensitizes cancer cells by disturbing multiple DNA damage responses.

  9. High levels of Dnmt3b expression prolong leukemia latency.

  10. The expression of DNMT1 (show DNMT1 Antibodies) and DNMT3b was decreased at 1 mT, and 50 Hz ELF (show SPTBN1 Antibodies)-EMF can increase the expression...the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF (show SPTBN1 Antibodies)-EMF exposure

DNMT3B Antigen Profile

Protein Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Gene names and symbols associated with DNMT3B

  • DNA (cytosine-5-)-methyltransferase 4 (dnmt4) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (LOC100218113) antibody
  • DNA methyltransferase 3B (dnmt3b) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (dnmt3b) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (Dnmt3b) antibody
  • DNA methyltransferase 3B (Dnmt3b) antibody
  • cb91 antibody
  • cb633 antibody
  • DNMT3B antibody
  • dnmt3bl antibody
  • dnmt7 antibody
  • ICF antibody
  • ICF1 antibody
  • LOC100218113 antibody
  • M.HsaIIIB antibody
  • MmuIIIB antibody
  • sb:cb91 antibody
  • wu:fb16h07 antibody

Protein level used designations for DNMT3B

DNA (cytosine-5)-methyltransferase 3B , DNA (cytosine-5-)-methyltransferase 3 beta , DNA cytosine-5 methyltransferase 3 beta , DNA (cytosine-5)-methyltransferase 3B-like , DNA methyl transferase beta , DNA methyltransferase 3B , DNA MTase HsaIIIB , DNA methyltransferase HsaIIIB , DNA (cytosine-5-)-methyltransferase 3 beta, like , DNA (cytosine-5-)-methyltransferase 7 , fb16h07 , DNA MTase MmuIIIB , DNA methyltransferase MmuIIIB

GENE ID SPECIES
317744 Danio rerio
458174 Pan troglodytes
711553 Macaca mulatta
100053900 Equus caballus
100218113 Taeniopygia guttata
100412936 Callithrix jacchus
100459992 Pongo abelii
100466728 Ailuropoda melanoleuca
100500777 Ovis aries
100598378 Nomascus leucogenys
100528060 Anolis carolinensis
1789 Homo sapiens
321084 Danio rerio
419287 Gallus gallus
100302109 Sus scrofa
353354 Bos taurus
444985 Rattus norvegicus
13436 Mus musculus
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