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anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Antibodies

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. Additionally we are shipping DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCLRE1B 64858 Q9H816
DCLRE1B 310745 Q4KLY6
DCLRE1B 140917 Q8C7W7
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Top anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB DCLRE1B Antibody (Center)(ABIN651618) western blot analysis in mouse kidney tissue lysates (35 µg/lane). This demonstrates the DCLRE1B antibody detected DCLRE1B protein (arrow). DCLRE1B Antibody (Center) (ABIN651618) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC205744 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DCLRE1B antibody (ABIN2454181), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCLRE1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DCLRE1B. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of DCLRE1B expression in HOS (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated FACS   100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

DCLRE1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) ,


Top referenced anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Antibodies

  1. Human Polyclonal DCLRE1B Primary Antibody for IHC (p), WB - ABIN651618 : Bae, Mukhopadhyay, Liu, Zhang, Tan, Akhter, Liu, Shen, Li, Legerski: Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links. in Oncogene 2008 (PubMed)
    Show all 4 references for ABIN651618

More Antibodies against DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Interaction Partners

Human DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Different charge distributions along the DNA binding groove may account for the drastic difference in processivity and DNA digestion efficiency, including that of damaged substrates, between SNM1A (show DCLRE1A Antibodies) and SNM1B.

  2. The SNM1B/APOLLO DNA nuclease (show DCLRE1C Antibodies) functions in resolution of replication stress and maintenance of common fragile site stability.

  3. the N-terminal region of Snm1B forms a complex containing PSF2 (show TAP2 Antibodies) and Mus81 (show MUS81 Antibodies), while the C-terminal region is important for PSF2 (show TAP2 Antibodies)-mediated chromatin association.

  4. The nuclease (show DCLRE1C Antibodies) hSNM1B/Apollo is linked to the Fanconi anemia (show PALB2 Antibodies) pathway via its interaction with FANCP/SLX4 (show BTBD12 Antibodies).

  5. differences in the substrate selectivities of SNM1A (show DCLRE1A Antibodies) and SNM1B are likely to be relevant to their in vivo roles

  6. SNM1B functions epistatically to the central Fanconi anemia (show PALB2 Antibodies) factor, FANCD2 (show FANCD2 Antibodies), in cellular survival after interstrand crosslinks damage and homology-directed repair of DNA double-strand breaks

  7. TRF2 (show TERF2 Antibodies), which binds preferentially to positively supercoiled DNA substrates, together with Apollo, negatively regulates the amount of TOP1 (show TOP1 Antibodies), TOP2alpha, and TOP2beta (show TOP2B Antibodies) at telomeres.

  8. siRNA knockdown of hSNM1B rendered cells sensitive to ionizing radiation, suggesting the possibility of hSNM1B involvement in homologous recombination repair of double-strand breaks arising as intermediates of ICL repair

  9. the C terminus of Snm1B was shown to interact with the TRF (show IL5 Antibodies) homology domain of TRF2 (show TERF2 Antibodies) indicating that Snm1B is likely recruited to the telomere via interaction with the double-stranded telomere-binding protein TRF2 (show TERF2 Antibodies)

  10. SNM1B (Apollo) protein exhibits a 5'-to-3' DNA exonuclease (show EXO1 Antibodies) activity and functions together with TRF2 (show TERF2 Antibodies) to protect telomeres from damage and fusion.

Mouse (Murine) DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Study documents the combinatorial action of Apollo, POT1b, CST (show CORT Antibodies), and the 5' exonuclease (show EXO1 Antibodies) Exo1 (show EXO1 Antibodies) in postreplicative telomere end processing in mouse cells, clarifying the mechanism by which the telomeric 3' overhang is generated and modulated.

  2. The telomeric protein (show SYCE1 Antibodies) SNM1B/Apollo is required for normal cell proliferation and embryonic development

  3. TRF2 (show TERF2 Antibodies)-bound Apollo functions at replicating telomeres, promoting the maintenance of the telomeric overhang, repressing S phase-specific ATM (show ATM Antibodies) signaling, and protecting leading-end telomeres from fusion.

  4. Apollo null mouse embryo fibroblasts exhibit an increased incidence of G2 chromatid-type fusions involving telomeres created by leading-strand DNA synthesis, reflective of a failure to protect these telomeres after DNA replication.

DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Antigen Profile

Protein Summary

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000

Gene names and symbols associated with DCLRE1B

  • DNA cross-link repair 1B (DCLRE1B) antibody
  • DNA cross-link repair 1B (Dclre1b) antibody
  • DNA cross-link repair 1B (dclre1b) antibody
  • DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae) (Dclre1b) antibody
  • AI452214 antibody
  • Apollo antibody
  • im:6894074 antibody
  • mSNM1B antibody
  • SNM1B antibody
  • SNMIB antibody
  • zgc:154089 antibody

Protein level used designations for DCLRE1B

5' exonuclease Apollo , DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) , PSO2 homolog , SNM1 homolog B , DNA cross-link repair 1B protein

GENE ID SPECIES
64858 Homo sapiens
428269 Gallus gallus
310745 Rattus norvegicus
768137 Danio rerio
140917 Mus musculus
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