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DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) ELISA Kits

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. Additionally we are shipping DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Antibodies (28) and DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human DCLRE1B DCLRE1B 64858 Q9H816
Anti-Rat DCLRE1B DCLRE1B 310745 Q4KLY6
Anti-Mouse DCLRE1B DCLRE1B 140917 Q8C7W7
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More ELISA Kits for DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Interaction Partners

Human DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Different charge distributions along the DNA binding groove may account for the drastic difference in processivity and DNA digestion efficiency, including that of damaged substrates, between SNM1A (show DCLRE1A ELISA Kits) and SNM1B.

  2. The SNM1B/APOLLO DNA nuclease (show DCLRE1C ELISA Kits) functions in resolution of replication stress and maintenance of common fragile site stability.

  3. the N-terminal region of Snm1B forms a complex containing PSF2 (show TAP2 ELISA Kits) and Mus81 (show MUS81 ELISA Kits), while the C-terminal region is important for PSF2 (show TAP2 ELISA Kits)-mediated chromatin association.

  4. The nuclease (show DCLRE1C ELISA Kits) hSNM1B/Apollo is linked to the Fanconi anemia (show PALB2 ELISA Kits) pathway via its interaction with FANCP/SLX4 (show BTBD12 ELISA Kits).

  5. differences in the substrate selectivities of SNM1A (show DCLRE1A ELISA Kits) and SNM1B are likely to be relevant to their in vivo roles

  6. SNM1B functions epistatically to the central Fanconi anemia (show PALB2 ELISA Kits) factor, FANCD2 (show FANCD2 ELISA Kits), in cellular survival after interstrand crosslinks damage and homology-directed repair of DNA double-strand breaks

  7. TRF2 (show TERF2 ELISA Kits), which binds preferentially to positively supercoiled DNA substrates, together with Apollo, negatively regulates the amount of TOP1 (show TOP1 ELISA Kits), TOP2alpha, and TOP2beta (show TOP2B ELISA Kits) at telomeres.

  8. siRNA knockdown of hSNM1B rendered cells sensitive to ionizing radiation, suggesting the possibility of hSNM1B involvement in homologous recombination repair of double-strand breaks arising as intermediates of ICL repair

  9. the C terminus of Snm1B was shown to interact with the TRF (show IL5 ELISA Kits) homology domain of TRF2 (show TERF2 ELISA Kits) indicating that Snm1B is likely recruited to the telomere via interaction with the double-stranded telomere-binding protein TRF2 (show TERF2 ELISA Kits)

  10. SNM1B (Apollo) protein exhibits a 5'-to-3' DNA exonuclease (show EXO1 ELISA Kits) activity and functions together with TRF2 (show TERF2 ELISA Kits) to protect telomeres from damage and fusion.

Mouse (Murine) DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Study documents the combinatorial action of Apollo, POT1b, CST (show CORT ELISA Kits), and the 5' exonuclease (show EXO1 ELISA Kits) Exo1 (show EXO1 ELISA Kits) in postreplicative telomere end processing in mouse cells, clarifying the mechanism by which the telomeric 3' overhang is generated and modulated.

  2. The telomeric protein (show SYCE1 ELISA Kits) SNM1B/Apollo is required for normal cell proliferation and embryonic development

  3. TRF2 (show TERF2 ELISA Kits)-bound Apollo functions at replicating telomeres, promoting the maintenance of the telomeric overhang, repressing S phase-specific ATM (show ATM ELISA Kits) signaling, and protecting leading-end telomeres from fusion.

  4. Apollo null mouse embryo fibroblasts exhibit an increased incidence of G2 chromatid-type fusions involving telomeres created by leading-strand DNA synthesis, reflective of a failure to protect these telomeres after DNA replication.

DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Antigen Profile

Antigen Summary

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000

Gene names and symbols associated with DCLRE1B

  • DNA cross-link repair 1B (DCLRE1B) antibody
  • DNA cross-link repair 1B (Dclre1b) antibody
  • DNA cross-link repair 1B (dclre1b) antibody
  • DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae) (Dclre1b) antibody
  • AI452214 antibody
  • Apollo antibody
  • im:6894074 antibody
  • mSNM1B antibody
  • SNM1B antibody
  • SNMIB antibody
  • zgc:154089 antibody

Protein level used designations for DCLRE1B

5' exonuclease Apollo , DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) , PSO2 homolog , SNM1 homolog B , DNA cross-link repair 1B protein

GENE ID SPECIES
64858 Homo sapiens
428269 Gallus gallus
310745 Rattus norvegicus
768137 Danio rerio
140917 Mus musculus
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