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anti-DNA-Damage-Inducible Transcript 3 (DDIT3) Antibodies

DDIT3 encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. Additionally we are shipping DDIT3 Kits (27) and DDIT3 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DDIT3 13198 P35639
DDIT3 29467  
DDIT3 1649 P35638
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Top anti-DDIT3 Antibodies at antibodies-online.com

Showing 10 out of 197 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated FACS, IF, WB DDIT3 Antibody (C-term A135) (ABIN655895) western blot analysis in mouse testis tissue lysates (35 µg/lane). This demonstrates the DDIT3 antibody detected the DDIT3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, WB DDIT3 Antibody (Center) (ABIN656987) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the DDIT3 antibody detected the DDIT3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells treated with PMA 125ng/ml 30', using CHOP (Phospho-Ser30) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CHOP (Phospho-Ser30) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GADD153 / CHOP Antibody  in Jurkat cell line lysates (35ug/lane). This demonstrates the DDIT3 antibody detected the DDIT3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow Cytometric analysis of 293 cells using DIT3 Antibody (C-term) Cat.-No  AP51213PU-N (right histogram) compared to a Negative Control cell (left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Western blot analysis in Mouse testis tissue lysates (35ug/lane) using DDIT3 Antibody (C-term) Cat.-No  AP51213PU-N. This demonstrates the DDIT3 antibody detected the DDIT3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Anti-GADD153 Polyclonal Antibody, Unconjugated (ABIN685447) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IP, IHC, WB   100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details

DDIT3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DDIT3 Antibodies

  1. Mouse (Murine) Polyclonal DDIT3 Primary Antibody for FACS, IF - ABIN655895 : Park, Choi, Yang, Do, Kim, Moon: Repression of peroxisome proliferator-activated receptor gamma by mucosal ribotoxic insult-activated CCAAT/enhancer-binding protein homologous protein. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 3 references for ABIN655895

  2. Human Polyclonal DDIT3 Primary Antibody for EIA, WB - ABIN952423 : Goodall, Wu, Zhang, McNeill, Ellis, Saudek, Gaston: Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for ABIN952423

  3. Human Polyclonal DDIT3 Primary Antibody for EIA, FACS - ABIN952424 : Zhang, Ye, Su, Yuan, Liu, Stein, Yang: Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1. in Journal of virology 2010 (PubMed)
    Show all 3 references for ABIN952424

  4. Human Polyclonal DDIT3 Primary Antibody for IF, IHC - ABIN1531556 : Park, Luethy, Wang, Fargnoli, Fornace, McBride, Holbrook: Isolation, characterization and chromosomal localization of the human GADD153 gene. in Gene 1992 (PubMed)
    Show all 3 references for ABIN1531556

  5. Human Polyclonal DDIT3 Primary Antibody for IF (p), IHC (p) - ABIN685447 : Du, Zhou, Jia, Huang: SelK is a novel ER stress-regulated protein and protects HepG2 cells from ER stress agent-induced apoptosis. in Archives of biochemistry and biophysics 2010 (PubMed)
    Show all 2 references for ABIN685447

  6. Human Polyclonal DDIT3 Primary Antibody for IP, IHC - ABIN223141 : Zenkel, Kruse, Naumann, Schlötzer-Schrehardt: Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma. in Investigative ophthalmology & visual science 2007 (PubMed)

More Antibodies against DDIT3 Interaction Partners

Mouse (Murine) DNA-Damage-Inducible Transcript 3 (DDIT3) interaction partners

  1. this study demonstrates novel roles for the endoplasmic reticulum stress-response transducer PERK (show EIF2AK3 Antibodies) and a downstream effector of its activation, CHOP, in tubule cell production of fibronectin (show FN1 Antibodies)

  2. CHOP regulates not only apoptosis-related signaling but also ROS (show ROS1 Antibodies) formation and inflammation in renal tubular cells during ischemia/reperfusion (I/R). CHOP may play an important role in the pathophysiology of I/R-induced renal injury.

  3. As a dual function cytokine, IL-1alpha may contribute to the induction of CHOP intracellularly, while IL-1alpha released from necrotic cells accelerates steatohepatitis via induction of inflammatory cytokines by neighboring cells.

  4. TFEB (show TFEB Antibodies)-regulated signaling pathway for osteoblast differentiation is involved in ATF4 (show ATF4 Antibodies)/CHOP-dependent signaling pathway.

  5. CHOP expression in myeloid cells plays an important role in determining the magnitude and duration of inflammatory response in vivo by modulating expression of proinflammatory cytokines such as IL-6 (show IL6 Antibodies) in infiltrating macrophages.

  6. the ER stress-induced transcription factor, CHOP, at least in part, plays an important role in the development of bleomycin-induced pulmonary fibrosis

  7. Data indicate that transcription factor Chop does not play a significant causal role during retinal degeneration.

  8. Upregulation of PD-1 (show PDCD1 Antibodies) and PD-L1 (show CD274 Antibodies) was associated with marked increases in GADD153 during myocardial ischemic reperfusion injury.

  9. Chop deficiency prevents unilateral ureteral obstruction-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1 (show HMGB1 Antibodies)/TLR4 (show TLR4 Antibodies)/NFkappaB/IL-1beta (show IL1B Antibodies) signaling.

  10. findings suggest that the balance between XBP1 (show XBP1 Antibodies)-mediated adaptive and CHOP-dependent apoptotic UPR is critically important for beta-cell survival during ER stress.

Human DNA-Damage-Inducible Transcript 3 (DDIT3) interaction partners

  1. Data show CGK733 induced microtubule associated protein LC3B (show MAP1LC3B Antibodies) formation upstream of AMP-activated protein kinase (show PRKAA2 Antibodies) and protein kinase (show CDK7 Antibodies) RNA-like endoplasmic reticulum kinase/CCAAT-enhancer-binding protein homologous protein pathways and p21 Cip1 (show CDKN1A Antibodies) expression.

  2. Data suggest that HOXA-AS2 (show ARSA Antibodies) could be an oncogene (show RAB1A Antibodies) for GC partly through suppressing P21 (show CDKN1A Antibodies), PLK3 (show PLK3 Antibodies), and DDIT3 expression.

  3. FUS (show FUS Antibodies)-DDIT3 is uniquely regulated at the transcriptional as well as the post-translational level and that its expression level is important for myxoid liposarcoma tumour development.

  4. CGK733-induced intracellular calcium sequestration in pancreatic tumor cells is correlated with the PERK (show EIF2AK3 Antibodies)/CHOP signaling pathway and may also be involved in the dysregulations of calcium-binding proteins.

  5. Combined administration inhibited the cells most potently and time-dependently, decreased the expression of HO-1 (show HMOX1 Antibodies), and significantly increased the expression of ATF4 (show ATF4 Antibodies), CHOP, and Ire-1 (show ERN1 Antibodies) proteins expression levels

  6. Blockage of PERK (show EIF2AK3 Antibodies) signaling expression by siRNA not only significantly reduced the expression of CHOP.

  7. Up-regulation of CHOP is associated with Pancreatic Neuroendocrine Tumors.

  8. knockdown of a proton-sensing G protein-coupled receptor (show ADRA1A Antibodies) GPR4 (show GPR4 Antibodies) markedly reduced CHOP expression and endothelial cell apoptosis after hypoxia exposure.

  9. These data show that altered/impaired expression of mtDNA induces CHOP-10 expression in a signaling pathway that depends on the eIF2alpha (show EIF2A Antibodies)/ATF4 (show ATF4 Antibodies) axis of the integrated stress response rather than on the mitochondrial unfolded protein response.

  10. In a GRP78 (show HSPA5 Antibodies)-positive breast cancer subset, CHOP overexpression correlated with a lower risk of recurrence.

Xenopus laevis DNA-Damage-Inducible Transcript 3 (DDIT3) interaction partners

  1. CHOP (GADD153) is an inhibitor of Wnt (show WNT2 Antibodies)/TCF (show HNF4A Antibodies) signals

DDIT3 Antigen Profile

Protein Summary

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Gene names and symbols associated with DDIT3

  • DNA-damage-inducible transcript 3 (ddit3) antibody
  • DNA-damage inducible transcript 3 (Ddit3) antibody
  • DNA-damage-inducible transcript 3 (DDIT3) antibody
  • DNA-damage-inducible transcript 3 (Ddit3) antibody
  • DNA-damage-inducible transcript 3 (LOC100338439) antibody
  • CEBPZ antibody
  • CHOP antibody
  • CHOP-10 antibody
  • Chop10 antibody
  • GADD153 antibody
  • Xchop antibody

Protein level used designations for DDIT3

C/EBP homoologous protein 10 , C/EBP zeta , CCAAT/enhancer-binding protein homologous protein , DDIT-3 , DNA damage-inducible transcript 3 protein , c/EBP-homologous protein 10 , growth arrest and DNA-damage-inducible protein GADD153 , C/EBP homologous protein , growth arrest and DNA damage-inducible protein GADD153 , growth arrest and DNA damage-inducible , transcription factor GADD153 , C/EBP-homologous protein 10 , DNA-damage inducible transcript 3

GENE ID SPECIES
733816 Xenopus (Silurana) tropicalis
13198 Mus musculus
29467 Rattus norvegicus
1649 Homo sapiens
398615 Xenopus laevis
777788 Bos taurus
607439 Canis lupus familiaris
100857832 Gallus gallus
101787388 Cavia porcellus
100240743 Sus scrofa
100338439 Oryctolagus cuniculus
541600 Ovis aries
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