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Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.. Additionally we are shipping DDIT4L Proteins (8) and DDIT4L Kits (3) and many more products for this protein.
Showing 10 out of 59 products:
Human Monoclonal DDIT4L Primary Antibody for FACS, WB - ABIN2749082
Cuaz-Pérolin, Furman, Larigauderie, Legedz, Lasselin, Copin, Jaye, Searfoss, Yu, Duverger, Nègre-Salvayre, Fruchart, Rouis: REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death. in Arteriosclerosis, thrombosis, and vascular biology 2004
Show all 3 references for ABIN2749082
Human Monoclonal DDIT4L Primary Antibody for FACS, WB - ABIN2749146
Corradetti, Inoki, Guan: The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. in The Journal of biological chemistry 2005
Show all 3 references for ABIN2749146
RTP801 (show DDIT4 Antibodies) and RTP801L work downstream of AKT (show AKT1 Antibodies) and upstream of TSC2 (show TSC2 Antibodies) to inhibit mTOR (show FRAP1 Antibodies) functions
mediates monocyte cell death through a reduction in thioredoxin-1 expression
Promoter methylation and differential gene expression of five markers: COL1A2, NPM2, HSPB6, DDIT4L and MT1G were validated by sequencing of bisulfite-modified DNA and real-time reverse transcriptase PCR, respectively.
Axonal injury-induced upregulation of the stress-responsive REDD2 leads to mTOR (show FRAP1 Antibodies) inhibition triggering early dendritic arbor retraction, neuronal dysfunction and subsequent death of adult retinal neurons.
IRF-1 (show IRF1 Antibodies) physically interacts with REDD2 in the large cytoplasmic protein (show BLZF1 Antibodies) complex
SMHS1 was found to be expressed in skeletal muscle, and comparisons of its expression in atrophied versus hypertrophied muscles and in oxidative versus glycolytic muscles suggested that SMHS1 contributes to muscle energy metabolism phenotypes.
REDD2 is enriched in skeletal muscle and inhibits mTOR (show FRAP1 Antibodies) signaling in response to leucine and stretch.
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
DNA damage-inducible transcript 4-like protein
, DNA-damage-inducible transcript 4-like
, HIF-1 responsive protein RTP801-like
, homolog of mouse SMHS1
, protein regulated in development and DNA damage response 2
, regulated in development and DNA damage response 2
, DNA-damage-inducible transcript 4-like protein
, skeletal muscle hindlimb suspension 1
, soleus muscle atrophied after hindlimb suspension protein 1