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Induces apoptotic cell death when co-expressed with DRAM1 (By similarity). Additionally we are shipping DNA-Damage Regulated Autophagy Modulator 2 Antibodies (9) and and many more products for this protein.
Genetic variants on chromosome 1p13.3 near the damage-regulated autophagy modulator 2 gene DRAM2 associated with Non-ST Elevation Myocardial Infarction (rs656843; odds ratio 1.57, P = 3.11 x 10(-10)) in the case-control analysis.
Recessive variants in DRAM2, an autophagy regulator gene, have been recently identified as a cause of retinal dystrophy (show MERTK ELISA Kits) with early macular involvement
Biallelic mutations in the autophagy regulator DRAM2 cause retinal dystrophy (show MERTK ELISA Kits) with early macular involvement.
The expression of damage-regulated autophagy modulator 2 (DRAM2) contributes to autophagy induction.
reduced expression of DRAM2 may contribute to enhanced cell survival in tumor cells.
DRAM2 is different from DRAM (show DRAM1 ELISA Kits) as it not induced by p53 (show TP53 ELISA Kits) or p73 (show TP73 ELISA Kits). DRAM2 is also a lysosomal protein, its overexpression does not modulate autophagy.
Induces apoptotic cell death when co-expressed with DRAM1 (By similarity).
DNA damage-regulated autophagy modulator protein 2
, Damage-regulated autophagy modulator
, DNA damage-regulated autophagy modulator protein 1
, DNA-damage regulated autophagy modulator 1
, damage-regulated autophagy modulator
, DNA-damage regulated autophagy modulator 2
, transmembrane protein 77
, damage regulated autophagy modulator 2
, VDNA-damage regulated autophagy modulator 2