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Dachshund Homolog 2 (Drosophila) Proteins (DACH2)

DACH2 is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. Additionally we are shipping DACH2 Antibodies (58) and DACH2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DACH2 93837 Q925Q8
DACH2 117154 Q96NX9
Rat DACH2 DACH2 302333  
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Top DACH2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DACH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Dachshund Homolog 2 (Drosophila) (DACH2) Interaction Partners

Zebrafish Dachshund Homolog 2 (Drosophila) (DACH2) interaction partners

Mouse (Murine) Dachshund Homolog 2 (Drosophila) (DACH2) interaction partners

  1. Dach2 and Hdac9 (show HDAC9 Proteins) mediate the effects of muscle activity on muscle reinnervation; Myog (show MYOG Proteins) and Gdf5 (show GDF5 Proteins) appear to stimulate muscle reinnervation through parallel pathways

  2. Unlike Drosophila dachshund mutants that lack eyes and exhibit leg truncations, the eyes and limbs of Dach (show DACH1 Proteins) double mutants are present, suggesting differences between Dach (show DACH1 Proteins) and dachshund gene function during embryonic eye and limb formation.

  3. a HDAC (show HDAC3 Proteins)-Dach2-myogenin (show MYOG Proteins) signaling pathway has been identified to decode nerve activity and control muscle gene expression in developing and adult skeletal muscle

  4. HDAC4 (show HDAC5 Proteins) is a neural activity-regulated deacetylase and a key signaling component that relays neural activity to the muscle transcriptional machinery through Dach2, myogenin (show MYOG Proteins), and nAChR (show CHRNA4 Proteins)

  5. With Dach1 (show DACH1 Proteins), may redundantly control female reproductive tract formation by regulating expression of target genes required for development of the Mullerian duct.

Human Dachshund Homolog 2 (Drosophila) (DACH2) interaction partners

  1. Exome sequencing in two brothers with distinct phenotype including congenital language disorder, growth retardation, intellectual disability and urinary and fecal incontinence, identifies missense mutations in ABCD1 and DACH2.

  2. DACH2 is an independent prognostic marker that can be used at initial diagnosis of urothelial carcinoma of the bladder to identify patients who have a high potential to develop metastasis.

  3. Most X;autosome translocations associated with premature ovarian failure do not interrupt X-linked genes. Only one of the six breakpoints disrupts a gene, DACH2.

DACH2 Protein Profile

Protein Summary

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DACH2

  • dachshund homolog 2 (Drosophila) (DACH2)
  • dachshund a (dacha)
  • dachshund homolog 2 (dach2)
  • dachshund 2 (Drosophila) (Dach2)
  • dachshund homolog 2 (Drosophila) (Dach2)
  • 9430028N04Rik protein
  • cb907 protein
  • RGD1561687 protein

Protein level used designations for DACH2

dachshund homolog 2 , dachshund homolog 2 (Drosophila) , dachshund homolog 2-like , dachshund 2

GENE ID SPECIES
100071693 Equus caballus
192121 Danio rerio
100101662 Xenopus (Silurana) tropicalis
742030 Pan troglodytes
100409967 Callithrix jacchus
100443501 Pongo abelii
100597661 Nomascus leucogenys
93837 Mus musculus
496011 Xenopus laevis
395576 Gallus gallus
117154 Homo sapiens
612847 Canis lupus familiaris
614223 Bos taurus
302333 Rattus norvegicus
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